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Cyclin A

Cyclin A is a member of the cyclin family, a group of proteins that function in regulating progression through the cell cycle. The stages that a cell passes through that culminate in its division and replication are collectively known as the cell cycle Since the successful division and replication of a cell is essential for its survival, the cell cycle…

Role in cell cycle progression, Regulation & Types

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Key facts & relationships

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Domains
InterPro
HGNC
1577
Locus
Chr. 13 q12.3-q13
NCBI gene
8900
OMIM
604036
RefSeq
NM_003914

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Overview

Types

Role in cell cycle progression

Regulation

Advanced semantic analysis

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Map overview Semantic statistics

Cyclin A

Nodes50
Edges49
Triples92
Avg. degree1.96
Density0.04
Components1

How this topic connects Entity context

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Cyclin A

Top relations

related to G2 / M phase · 13
Cyclin A → A/CDK1, A/CDK2, B/CDK1, CDK1, Cyclin, Cyclin A/CDK1, Cyclin A/CDK2, Degradation, G2, In, It, New, Once
related to p53 and p21 · 13
Cyclin A → A-CDK2/1, Activated, CDK, CDKs, Cell, D/CDK4, DNA, E2F, G1, P21, P53, PRb, Transcription
related to S phase · 13
Cyclin A → A/CDK2, As, CDC6, CDK2, Cyclin, Cyclin A/CDK2, DNA, E/CDK2, G1, In, Since, This, When
related to CDK partner association · 10
Cyclin A → Association, CDK, CDK1, CDK2, CDKs, Cyclin, Depending, G2, PSTAIRE, The
related to E2F and pRb · 10
Cyclin A → After, Cyclin, D/E, E2F, G1, Hyperphosphorylated, Hypophosphorylated, It, The, Transcription
related to Types · 9
Cyclin A → A1, A2, Cyclin, Cyclin A1, Cyclin A2, Drosophila, Since, The, Xenopus
related to External links · 5
Cyclin A → Drosophila Cyclin, Medicine Medical Subject Headings, MeSH, National Library, The Interactive FlyCyclin
related to Regulation · 4
Cyclin A → G1, G2, Initiation, Transcription
related to Role in cell cycle progression · 3
Cyclin A → CDK, CDKs, Cyclin
is a · 2
Cyclin A → member of the cyclin family, only cyclin that regulates multiple steps of the cell cycle

Important terminology Word statistics

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Important terminology

cyclin cell cdk2 cycle transcription phase e2f progression cdk1 complex prb g2 replication binds dna regulated cdk role p21 drosophila

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cyclin ADomainsInterPro1.00infobox
Cyclin AHGNC15771.00infobox
Cyclin ALocusChr. 13 q12.3-q131.00infobox
Cyclin ANCBI gene89001.00infobox
Cyclin AOMIM6040361.00infobox
Cyclin ARefSeqNM_0039141.00infobox
Cyclin ASearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Cyclin AStructuresSwiss-model1.00infobox
Cyclin ASymbolCCNA11.00infobox
Cyclin AUniProtP783961.00infobox
Cyclin Ais amember of the cyclin family0.90text
Cyclin Ais aonly cyclin that regulates multiple steps of the cell cycle0.90text

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    Min side: 3
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