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Cdc6

Cdc6, or cell division cycle 6, is a protein in eukaryotic cells. It is mainly studied in the budding yeast Saccharomyces cerevisiae (P09119). It is an essential regulator of DNA replication and plays important roles in the activation and maintenance of the checkpoint mechanisms in the cell cycle that coordinate S phase and mitosis. It is part of the…

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AlphaFold
IPR016314
Available protein structures:
IPR016314
InterPro
IPR016314
PDB
IPR016314
Symbol
Cdc6

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Overview

Function

Regulation

Structure

Disease

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Map overview Semantic statistics

Cdc6

Nodes39
Edges38
Triples64
Avg. degree1.95
Density0.051282
Components1

How this topic connects Entity context

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Cdc6

Top relations

related to Function · 18
Cdc6 → ATP, CDC28, CDC6-Cdt1, Cdt1, DNA, EM, Furthermore, It, MCM, MCM2-7p, Mutations, OCCM, ORC, ORC-CDC6, ORC-Cdc6-Cdt1-Mcm2-7, RC, Reconstruction, The
related to Regulation · 18
Cdc6 → Cdc28-Clb5-Clb6, Cdc28-Cln, CDK, Cdk2, Cdk2-activity, DNA, G1, In, It, N-terminus, Nevertheless, On, RC, SCFCDC4-dependent, The, This, Thus, Two
related to Structure · 16
Cdc6 → AAA, ATP, ATP/ADP, ATPases, Cdc6/Orc1-related, DNA, Domain, Domain III, From, II, III, Nevertheless, Pyrobaculum, RC, The, These
related to Disease · 7
Cdc6 → DNA, Down-regulation, Furthermore, In, INK4/ARF, It, These
AlphaFold · 1
Cdc6 → IPR016314
Available protein structures: · 1
Cdc6 → IPR016314
InterPro · 1
Cdc6 → IPR016314
PDB · 1
Cdc6 → IPR016314
Symbol · 1
Cdc6 → Cdc6

Important terminology Word statistics

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Important terminology

dna protein complex cell cycle atp phase cells pre-rc mcm essential binding thus g1 domains activation loading aaa atpases maintenance

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cdc6AlphaFoldIPR0163141.00infobox
Cdc6Available protein structures:IPR0163141.00infobox
Cdc6InterProIPR0163141.00infobox
Cdc6PDBIPR0163141.00infobox
Cdc6SymbolCdc61.00infobox
Cdc6related to DiseaseIt0.60section
Cdc6related to DiseaseINK4/ARF0.60section
Cdc6related to DiseaseIn0.60section
Cdc6related to DiseaseDNA0.60section
Cdc6related to DiseaseThese0.60section
Cdc6related to DiseaseDown-regulation0.60section
Cdc6related to DiseaseFurthermore0.60section

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    Min side: 3
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