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Citalopram

Citalopram, sold under the brand name Celexa among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used to treat major depressive disorder, obsessive compulsive disorder, panic disorder, and social anxiety disorder. The antidepressant effects may take one to four weeks to occur. It is typically taken orally…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N06AB04 (WHO)
Bioavailability
80% peak at 4 hours
CAS Number
59729-33-8 Y
ChEBI
CHEBI:3723 Y

Topics to explore

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Overview

Medical uses

Administration

Adverse effects

Interactions

Pharmacology

Stereochemistry

Metabolism

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Citalopram

Nodes128
Edges127
Triples255
Avg. degree1.98
Density0.015625
Components1

How this topic connects Entity context

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Citalopram

Top relations

related to Brand names · 99
Citalopram → Actavis, Akarin, Argentina, Australia, Belgium, Bolivia, Brazil, Canada, Celapram, Celexa, Celica, Chile, Ciazil, Cilate, Cilift, Cinapen, Cipram, Cipramil, Cipraned, Ciprapine
related to Serotonin syndrome · 17
Citalopram → However, HTP, It, MAOIs, MDMA, P450, Serotonin, SERT, SRA, SRAs, SSRI, SSRIs, St John's, This, Tryptophan, When, With St John's
related to Metabolism · 10
Citalopram → After, Approximately, CYP2C19, CYP2D6, CYP3A4, Metabolites, Potent, The, Tobacco, With
related to European Commission fine · 8
Citalopram → Danish, European, European Commission, June, Lundbeck, Lundbeck's, On, This
related to Post-SSRI sexual dysfunction · 8
Citalopram → Characteristic, In, PSSD, Sexual, SSRI, SSRIs, The, The DSM-5
has effect · 7
Citalopram → As, If, Less, Other, Rare, Some, SSRIs
related to Stereochemistry · 7
Citalopram → As, In, Lundbeck, N-dimethyl-3-aminopropyl, Only, They, Whereas
related to Depression · 6
Citalopram → Clinical Excellence, Evidence, Health, In, National Institute, United States
related to history · 6
Citalopram → Denmark, It, Klaus Bøgesø, Lundbeck, The, US
related to Overdose · 6
Citalopram → Blood, It, N-desmethylcitalopram, Overdosage, Overdose, SSRIs

Important terminology Word statistics

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Important terminology

serotonin may effects ssris side risk sexual european taken disorder also dysfunction ssri escitalopram patients including nausea syndrome antidepressant -citalopram

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Citalopram3D model (JSmol)Interactive image1.00infobox
CitalopramAHFS/Drugs.comMonograph1.00infobox
CitalopramATC codeN06AB04 (WHO)1.00infobox
CitalopramBioavailability80% peak at 4 hours1.00infobox
CitalopramCAS Number59729-33-8 Y1.00infobox
CitalopramChEBICHEBI:3723 Y1.00infobox
CitalopramChEMBLChEMBL549 Y1.00infobox
CitalopramChemSpider2669 Y1.00infobox
CitalopramChiralityRacemic mixture1.00infobox
CitalopramCompTox Dashboard (EPA)DTXSID80228261.00infobox
CitalopramDependence liabilityLow/none1.00infobox
CitalopramDrug classSelective serotonin reuptake inhibitor (SSRI)1.00infobox
CitalopramDrugBankDB00215 Y1.00infobox
CitalopramECHA InfoCard100.056.2471.00infobox
CitalopramElimination half-life35 hours1.00infobox
CitalopramExcretionMostly as unmetabolized citalopram, partly DCT, and traces of DDCT in urine1.00infobox
CitalopramFormulaC20H21FN2O1.00infobox
CitalopramIUPHAR/BPS75471.00infobox
CitalopramKEGGD07704 Y1.00infobox
CitalopramKEGGas salt: D00822 Y1.00infobox
CitalopramLegal statusAU: S4 (Prescription only)1.00infobox
CitalopramLegal statusBR: Class C1 (Other controlled substances)1.00infobox
CitalopramLegal statusCA: ℞-only1.00infobox
CitalopramLegal statusUK: POM (Prescription only)1.00infobox
CitalopramLegal statusUS: ℞-only1.00infobox
CitalopramLicense dataUS DailyMed: Citalopram1.00infobox
CitalopramMedlinePlusa6990011.00infobox
CitalopramMetabolismLiver (CYP3A4 and CYP2C19)1.00infobox
CitalopramMetabolitesDesmethylcitalopram (DCT) and didesmethylcitalopram (DDCT)1.00infobox
CitalopramMolar mass324.399 g·mol−11.00infobox

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