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BTF3: Art, Properties & Biological role

Basic transcription factor 3 is a eukaryotic protein that in humans is encoded by the BTF3 gene. They are very important to the development of many eukaryotic organisms such as in humans, plants, fungi, and protists. Some of the functions it plays a part in are gene expression regulation, cell proliferation control, protein homeostasis maintenance, and…

Language: English [EN]
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BTF3 topic overview

The analysis highlights Art, Properties and Biological role as prominent areas in the source structure around BTF3.

Related topics
47
Source areas
4
Connected nodes
51
Extracted relationships
145
Concept neighborhoods
22
Bridge connections
51

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 18 topics
Properties · 16 topics
Biological role · 10 topics
Interactions · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BTF3, BETA-NAC, BTF3a, BTF3b, NACB, basic transcription factor 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LKX, 3MCB
Band
5q13.2 · 13|13 D1
Bgee
mucosa of sigmoid colon · lactiferous duct · human penis · left ovary · embryo
BioGPS
n/a
Chr.
Chromosome 5 (human) · Chromosome 13 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Properties

Biological role

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BTF3 connects Entity context

The extracted context around BTF3 shows recurring relationship patterns in the source. For example, BTF3 → Bax, Bcl-2, E-cadherin, EMT, EMT-related, FOXM1, G2/M, IL-6, In, It, JAK2, JAK2/STAT3, Ki-67, N-cadherin, PCNA, PDCD2L, Regulation, STAT3, STAT3s, TFII Another extracted example is BTF3 → blastocyst, cartilage tissue, embryo, epiblast, ganglionic eminence, human penis, lactiferous duct, left ovary, lens, mucosa of sigmoid colon, oral cavity, thymus, trabecular bone, uterus, ventricular zone, vulva, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

BTF3

Top relations

related to Regulations · 24
BTF3 → Bax, Bcl-2, E-cadherin, EMT, EMT-related, FOXM1, G2/M, IL-6, In, It, JAK2, JAK2/STAT3, Ki-67, N-cadherin, PCNA, PDCD2L, Regulation, STAT3, STAT3s, TFII
Bgee · 17
BTF3 → blastocyst, cartilage tissue, embryo, epiblast, ganglionic eminence, human penis, lactiferous duct, left ovary, lens, mucosa of sigmoid colon, oral cavity, thymus, trabecular bone, uterus, ventricular zone, vulva, yolk sac
RNA expression pattern · 17
BTF3 → blastocyst, cartilage tissue, embryo, epiblast, ganglionic eminence, human penis, lactiferous duct, left ovary, lens, mucosa of sigmoid colon, oral cavity, thymus, trabecular bone, uterus, ventricular zone, vulva, yolk sac
related to Structure · 14
BTF3 → BTF3's, BTF3's C-terminal, BTF3a, BTFb, In, It's, N-terminal, NAC, Nascent Polypeptide-Associated Complex, The, The BTF3a, The NAC, This, Using
Gene ontology · 13
BTF3 → cytoplasm, cytosol, in utero embryonic development, nascent polypeptide-associated complex, nucleus, polysomal ribosome, protein binding, protein transport, regulation of transcription, DNA-templated, RNA binding, transcription by RNA polymerase II, transcription, DNA-templated, transport
related to Composition · 9
BTF3 → BTF3's, DNA, In, It, N-terminal, NAC, Post-translational, The C-terminal NAC, There's
related to Biological role · 7
BTF3 → II, Its, NAC, RNA, So, The, This
related to Solubility · 6
BTF3 → BTF3's, II, Its, NAC, RNA, The
related to External links · 5
BTF3 → Human BTF3, Human Transcription, PDB, PDBe-KB, UCSC Genome Browser
is a · 3
BTF3 → critical upstream regulator of this cancer-causing transcription factor, cytosolic/nuclear, β-subunit of the Nascent Polypeptide-Associated Complex

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

transcription protein gene important expression cancer factor regulation complex human foxm1 bp signaling pdcd2l cellular nascent chr band regulates emt

BTF3 relationships Subject–Predicate–Object triples

TTTA extracted 145 structured relationships around BTF3. Examples in this analysis include BTF3 → Aliases → BTF3, BETA-NAC, BTF3a, BTF3b, NACB, basic transcription factor 3 and BTF3 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LKX, 3MCB. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
BTF3AliasesBTF3, BETA-NAC, BTF3a, BTF3b, NACB, basic transcription factor 31.00infobox
BTF3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LKX, 3MCB1.00infobox
BTF3Band5q13.21.00infobox
BTF3Band13|13 D11.00infobox
BTF3Bgeemucosa of sigmoid colon1.00infobox
BTF3Bgeelactiferous duct1.00infobox
BTF3Bgeehuman penis1.00infobox
BTF3Bgeeleft ovary1.00infobox
BTF3Bgeeembryo1.00infobox
BTF3Bgeevulva1.00infobox
BTF3Bgeeganglionic eminence1.00infobox
BTF3Bgeeoral cavity1.00infobox
BTF3Bgeetrabecular bone1.00infobox
BTF3Bgeecartilage tissue1.00infobox
BTF3Bgeeepiblast1.00infobox
BTF3Bgeelens1.00infobox
BTF3Bgeeventricular zone1.00infobox
BTF3Bgeeyolk sac1.00infobox
BTF3Bgeethymus1.00infobox
BTF3Bgeeblastocyst1.00infobox
BTF3Bgeeuterus1.00infobox
BTF3BioGPSn/a1.00infobox
BTF3Chr.Chromosome 5 (human)1.00infobox
BTF3Chr.Chromosome 13 (mouse)1.00infobox
BTF3DatabasesNCBI: entry; OMA: entry1.00infobox
BTF3End73,505,667 bp1.00infobox
BTF3End98,453,514 bp1.00infobox
BTF3EnsemblENSG000001457411.00infobox
BTF3Entrez6891.00infobox
BTF3External IDsOMIM: 602542; MGI: 1202875; GeneCards: BTF31.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BTF3 bring nearby vocabulary together. In this analysis, examples include Transcription, Pdcd2l and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • BTF3
    • Transcription
    • Pdcd2l
    • Gene
    • Regulates
    • Factor
    • Regulation
    • Signaling
    • Foxm1
    • Cancer
    • Important
    • Protein
    • Jak2
  • btf3
    • Transcription
    • Pdcd2l
    • Gene
    • Regulates
    • Factor
    • Regulation
    • Signaling
    • Foxm1
    • Cancer
    • Important
    • Protein
    • Jak2
  • protein
    • Gene
    • Regulation
    • Transcription
    • Expression
    • Nascent
    • Btf3
    • Band
    • Biological
    • Chromosome
    • Development
    • Forms
    • Humans
  • gene
    • Expression
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Transcription
    • Protein
    • Regulates
    • Band
    • Biological
    • Development
  • gene expression regulation
    • Expression
    • Gene
    • Location
    • Human
    • Chromosome
    • Proliferation
    • Bp
    • Chr
    • Regulates
    • Transcription
    • Protein
    • Band
  • protein homeostasis
    • Gene
    • Regulation
    • Transcription
    • Expression
    • Nascent
    • Btf3
    • Band
    • Biological
    • Chromosome
    • Development
    • Forms
    • Humans
  • α-helical protein
    • Gene
    • Regulation
    • Transcription
    • Expression
    • Nascent
    • Btf3
    • Band
    • Biological
    • Chromosome
    • Development
    • Forms
    • Humans
  • transcription
    • Factor
    • Btf3
    • Ii
    • Polymerase
    • Rna
    • Promoter
    • Gene
    • Biological
    • Protein
    • Human
    • Complex
    • Expression

Connections between topic areas Semantic bridges

For BTF3, one of the stronger structural bridges in this analysis connects BTF3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BTF3Overview · splits 33 ⟂ 19
BTF3Properties · splits 35 ⟂ 17
BTF3Biological role · splits 41 ⟂ 11
BTF3Interactions · splits 48 ⟂ 4

Map overview Semantic statistics

BTF3

Nodes52
Edges51
Triples145
Avg. degree1.96
Density0.038462
Components1

Source & methodology

TTTA analyzes the structure around BTF3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Properties & Biological role, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BTF3 · EN edition · Analysis: TopicsToTalkAbout

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