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BTF3

Basic transcription factor 3 is a eukaryotic protein that in humans is encoded by the BTF3 gene. They are very important to the development of many eukaryotic organisms such as in humans, plants, fungi, and protists. Some of the functions it plays a part in are gene expression regulation, cell proliferation control, protein homeostasis maintenance, and…

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Aliases
BTF3, BETA-NAC, BTF3a, BTF3b, NACB, basic transcription factor 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LKX, 3MCB
Band
5q13.2 · 13|13 D1
Bgee
mucosa of sigmoid colon · lactiferous duct · human penis · left ovary · embryo
BioGPS
n/a
Chr.
Chromosome 5 (human) · Chromosome 13 (mouse)

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Map overview Semantic statistics

BTF3

Nodes52
Edges51
Triples145
Avg. degree1.96
Density0.038462
Components1

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BTF3

Top relations

related to Regulations · 24
BTF3 → Bax, Bcl-2, E-cadherin, EMT, EMT-related, FOXM1, G2/M, IL-6, In, It, JAK2, JAK2/STAT3, Ki-67, N-cadherin, PCNA, PDCD2L, Regulation, STAT3, STAT3s, TFII
Bgee · 17
BTF3 → blastocyst, cartilage tissue, embryo, epiblast, ganglionic eminence, human penis, lactiferous duct, left ovary, lens, mucosa of sigmoid colon, oral cavity, thymus, trabecular bone, uterus, ventricular zone, vulva, yolk sac
RNA expression pattern · 17
BTF3 → blastocyst, cartilage tissue, embryo, epiblast, ganglionic eminence, human penis, lactiferous duct, left ovary, lens, mucosa of sigmoid colon, oral cavity, thymus, trabecular bone, uterus, ventricular zone, vulva, yolk sac
related to Structure · 14
BTF3 → BTF3's, BTF3's C-terminal, BTF3a, BTFb, In, It's, N-terminal, NAC, Nascent Polypeptide-Associated Complex, The, The BTF3a, The NAC, This, Using
Gene ontology · 13
BTF3 → cytoplasm, cytosol, in utero embryonic development, nascent polypeptide-associated complex, nucleus, polysomal ribosome, protein binding, protein transport, regulation of transcription, DNA-templated, RNA binding, transcription by RNA polymerase II, transcription, DNA-templated, transport
related to Composition · 9
BTF3 → BTF3's, DNA, In, It, N-terminal, NAC, Post-translational, The C-terminal NAC, There's
related to Biological role · 7
BTF3 → II, Its, NAC, RNA, So, The, This
related to Solubility · 6
BTF3 → BTF3's, II, Its, NAC, RNA, The
related to External links · 5
BTF3 → Human BTF3, Human Transcription, PDB, PDBe-KB, UCSC Genome Browser
is a · 3
BTF3 → critical upstream regulator of this cancer-causing transcription factor, cytosolic/nuclear, β-subunit of the Nascent Polypeptide-Associated Complex

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Important terminology

transcription protein gene important expression cancer factor regulation complex human foxm1 bp signaling pdcd2l cellular nascent chr band regulates emt

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
BTF3AliasesBTF3, BETA-NAC, BTF3a, BTF3b, NACB, basic transcription factor 31.00infobox
BTF3Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3LKX, 3MCB1.00infobox
BTF3Band5q13.21.00infobox
BTF3Band13|13 D11.00infobox
BTF3Bgeemucosa of sigmoid colon1.00infobox
BTF3Bgeelactiferous duct1.00infobox
BTF3Bgeehuman penis1.00infobox
BTF3Bgeeleft ovary1.00infobox
BTF3Bgeeembryo1.00infobox
BTF3Bgeevulva1.00infobox
BTF3Bgeeganglionic eminence1.00infobox
BTF3Bgeeoral cavity1.00infobox
BTF3Bgeetrabecular bone1.00infobox
BTF3Bgeecartilage tissue1.00infobox
BTF3Bgeeepiblast1.00infobox
BTF3Bgeelens1.00infobox
BTF3Bgeeventricular zone1.00infobox
BTF3Bgeeyolk sac1.00infobox
BTF3Bgeethymus1.00infobox
BTF3Bgeeblastocyst1.00infobox
BTF3Bgeeuterus1.00infobox
BTF3BioGPSn/a1.00infobox
BTF3Chr.Chromosome 5 (human)1.00infobox
BTF3Chr.Chromosome 13 (mouse)1.00infobox
BTF3DatabasesNCBI: entry; OMA: entry1.00infobox
BTF3End73,505,667 bp1.00infobox
BTF3End98,453,514 bp1.00infobox
BTF3EnsemblENSG000001457411.00infobox
BTF3Entrez6891.00infobox
BTF3External IDsOMIM: 602542; MGI: 1202875; GeneCards: BTF31.00infobox

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