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Aurora kinase A: Aurora kinase family, Mitosis & Clinical significance

Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene.

Language: English [EN]
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Aurora kinase A topic overview

The analysis highlights Aurora kinase family, Mitosis and Clinical significance as prominent areas in the source structure around Aurora kinase A.

Related topics
55
Source areas
8
Connected nodes
63
Extracted relationships
151
Concept neighborhoods
21
Bridge connections
63

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Aurora kinase family · 12 topics
Mitosis · 10 topics
Clinical significance · 8 topics
Interactions · 7 topics
Overview · 7 topics
Meiosis · 5 topics
Discovery · 3 topics
Localization · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
Aliases
AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, aurora kinase A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4UZH, 1MQ4, 1MUO, 1OL5, 1OL6, 1OL7, 2BMC, 2C6D, 2C6E, 2DWB, 2J4Z, 2J50, 2NP8, 2W1C, 2W1D, 2W1E, 2W1F, 2W1G,…
Band
20q13.2 · 2 H3|2 94.84 cM
Bgee
oocyte · secondary oocyte · ventricular zone · sperm · gonad
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Aurora kinase family

Localization

Mitosis

Meiosis

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Aurora kinase A connects Entity context

The extracted context around Aurora kinase A shows recurring relationship patterns in the source. For example, Aurora kinase A → anaphase-promoting complex-dependent catabolic process, anterior/posterior axis specification, ATP binding, axon hillock, cell cycle, cell division, cell projection, cell projection organization, centriole, centrosome, centrosome cycle, centrosome localization, chromosome passenger complex, cilium, cytoplasm, cytoskeleton, cytosol, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G2/M transition of mitotic cell cycle, germinal vesicle Another extracted example is Aurora kinase A → amniotic fluid, embryo, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, morula, oocyte, otic placode, otic vesicle, primary oocyte, secondary oocyte, seminiferous tubule, sperm, testicle, trabecular bone, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

Aurora kinase A

Top relations

Gene ontology · 74
Aurora kinase A → anaphase-promoting complex-dependent catabolic process, anterior/posterior axis specification, ATP binding, axon hillock, cell cycle, cell division, cell projection, cell projection organization, centriole, centrosome, centrosome cycle, centrosome localization, chromosome passenger complex, cilium, cytoplasm, cytoskeleton, cytosol, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, G2/M transition of mitotic cell cycle, germinal vesicle
Bgee · 18
Aurora kinase A → amniotic fluid, embryo, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, morula, oocyte, otic placode, otic vesicle, primary oocyte, secondary oocyte, seminiferous tubule, sperm, testicle, trabecular bone, ventricular zone, zygote
RNA expression pattern · 18
Aurora kinase A → amniotic fluid, embryo, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, morula, oocyte, otic placode, otic vesicle, primary oocyte, secondary oocyte, seminiferous tubule, sperm, testicle, trabecular bone, ventricular zone, zygote
related to Aurora kinase family · 8
Aurora kinase A → Aurora, C-terminal, Caenorhabditis, Drosophila, In, The, The Xenopus, Their N-terminal
related to External links · 8
Aurora kinase A → APDBe-KB, AURKA, Human AURKA, Human Aurora, Mouse Aurora, PDB, PDBe-KB, UCSC Genome Browser
Band · 2
Aurora kinase A → 2 H3|2 94.84 cM, 20q13.2
Chr. · 2
Aurora kinase A → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
Aurora kinase A → 172,212,455 bp, 56,392,337 bp
2.7.11.1 · 1
Aurora kinase A → ↗
Aliases · 1
Aurora kinase A → AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, aurora kinase A

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

aurora kinase mitotic mitosis spindle protein cell meiosis human chromosome centrosome bp microtubules gene chr band proper aurka cytokinesis xenopus

Aurora kinase A relationships Subject–Predicate–Object triples

TTTA extracted 151 structured relationships around Aurora kinase A. Examples in this analysis include Aurora kinase A → 2.7.11.1 → ↗ and Aurora kinase A → Aliases → AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, aurora kinase A. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Aurora kinase A2.7.11.11.00infobox
Aurora kinase AAliasesAURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7, aurora kinase A1.00infobox
Aurora kinase AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4UZH, 1MQ4, 1MUO, 1OL5, 1OL6, 1OL7, 2BMC, 2C6D, 2C6E, 2DWB, 2J4Z, 2J50, 2NP8, 2W1C, 2W1D, 2W1E, 2W1F, 2W1G,…1.00infobox
Aurora kinase ABand20q13.21.00infobox
Aurora kinase ABand2 H3|2 94.84 cM1.00infobox
Aurora kinase ABgeeoocyte1.00infobox
Aurora kinase ABgeesecondary oocyte1.00infobox
Aurora kinase ABgeeventricular zone1.00infobox
Aurora kinase ABgeesperm1.00infobox
Aurora kinase ABgeegonad1.00infobox
Aurora kinase ABgeetrabecular bone1.00infobox
Aurora kinase ABgeeembryo1.00infobox
Aurora kinase ABgeeganglionic eminence1.00infobox
Aurora kinase ABgeeamniotic fluid1.00infobox
Aurora kinase ABgeetesticle1.00infobox
Aurora kinase ABgeezygote1.00infobox
Aurora kinase ABgeemorula1.00infobox
Aurora kinase ABgeeotic vesicle1.00infobox
Aurora kinase ABgeeseminiferous tubule1.00infobox
Aurora kinase ABgeeotic placode1.00infobox
Aurora kinase ABgeefetal liver hematopoietic progenitor cell1.00infobox
Aurora kinase ABgeeepiblast1.00infobox
Aurora kinase ABgeeprimary oocyte1.00infobox
Aurora kinase ABioGPSMore reference expression data1.00infobox
Aurora kinase AChr.Chromosome 20 (human)1.00infobox
Aurora kinase AChr.Chromosome 2 (mouse)1.00infobox
Aurora kinase ADatabasesNCBI: entry; OMA: entry1.00infobox
Aurora kinase AEnd56,392,337 bp1.00infobox
Aurora kinase AEnd172,212,455 bp1.00infobox
Aurora kinase AEnsemblENSG000000875861.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Aurora kinase A bring nearby vocabulary together. In this analysis, examples include Kinase, Mitotic and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Aurora kinase A
    • Kinase
    • Mitotic
    • Protein
    • Gene
    • Spindle
    • Meiosis
    • Activity
    • Mouse
    • Cycle
    • Family
    • Location
    • Bp
  • aurora kinase a
    • Protein
    • Kinase
    • Human
    • Meiosis
    • Mitotic
    • Gene
    • Xenopus
    • Spindle
    • Chromosome
    • Activity
    • Mouse
    • P53
  • gene
    • Location
    • Human
    • Bp
    • Chr
    • Activity
    • Chromosome
    • Mouse
    • Serine
    • Band
    • Meiosis
    • Kinase
    • Function
  • serine/threonine kinases
    • Serine
    • Centrosome
    • Mitotic
    • Activity
    • Function
    • Mitosis
    • Mouse
    • P53
    • Separation
    • Transition
    • Band
    • Cycle
  • cell proliferation
    • Cycle
    • Mitosis
    • Microtubules
    • Activity
    • Function
    • Transition
    • Cytokinesis
    • Centrosome
    • Mitotic
    • Meiosis
    • Spindle
    • Mouse
  • aurora kinases
    • Serine
    • Kinase
    • Centrosome
    • Mitotic
    • Protein
    • Activity
    • Function
    • Mitosis
    • Mouse
    • P53
    • Spindle
    • Band
  • xenopus
    • Meiosis
    • Kinase
    • Activity
    • Function
    • Mouse
    • P53
    • Protein
    • Serine
    • Aurka
    • Band
    • Cycle
    • Expression
  • aurora kinase b
    • Protein
    • Kinase
    • Human
    • Meiosis
    • Mitotic
    • Gene
    • Xenopus
    • Spindle
    • Chromosome
    • Activity
    • Mouse
    • P53

Connections between topic areas Semantic bridges

For Aurora kinase A, one of the stronger structural bridges in this analysis connects Aurora kinase A with Aurora kinase family. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Aurora kinase AAurora kinase family · splits 51 ⟂ 13
Aurora kinase AMitosis · splits 53 ⟂ 11
Aurora kinase AClinical significance · splits 55 ⟂ 9
Aurora kinase AOverview · splits 56 ⟂ 8
Aurora kinase AInteractions · splits 56 ⟂ 8
Aurora kinase AMeiosis · splits 58 ⟂ 6
Aurora kinase ADiscovery · splits 60 ⟂ 4
Aurora kinase ALocalization · splits 60 ⟂ 4

Map overview Semantic statistics

Aurora kinase A

Nodes64
Edges63
Triples151
Avg. degree1.97
Density0.03125
Components1

Source & methodology

TTTA analyzes the structure around Aurora kinase A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Aurora kinase family, Mitosis & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Aurora kinase A · EN edition · Analysis: TopicsToTalkAbout

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