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NME1: Interactions, Function & Overview

Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the NME1 gene. It is thought to be a metastasis suppressor.

Language: English [EN]
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NME1 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around NME1.

Related topics
13
Source areas
3
Connected nodes
16
Extracted relationships
133
Concept neighborhoods
9
Bridge connections
16

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 8 topics
Overview · 3 topics
Function · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
2.7.13.3
2.7.4.18
2.7.4.6
Aliases
NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1, NME/NM23 nucleoside diphosphate kinase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JXV, 1UCN, 2HVD, 2HVE, 3L7U, 4ENO

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How NME1 connects Entity context

The extracted context around NME1 shows recurring relationship patterns in the source. For example, NME1 → ATP binding, cell differentiation, cellular response to fatty acid, cellular response to glucose stimulus, centrosome, CTP biosynthetic process, cytoplasm, cytosol, deoxyribonuclease activity, DNA metabolic process, endocytosis, enzyme binding, extracellular exosome, gamma-tubulin binding, GTP binding, GTP biosynthetic process, hippocampus development, identical protein binding, intermediate filament, intermediate filament binding Another extracted example is NME1 → blastocyst, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, embryo, epiblast, ganglionic eminence, hippocampus proper, hypothalamus, islet of Langerhans, morula, neural tube, prefrontal cortex, primary visual cortex, proximal tubule, right frontal lobe, right kidney, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.

NME1

Top relations

Gene ontology · 57
NME1 → ATP binding, cell differentiation, cellular response to fatty acid, cellular response to glucose stimulus, centrosome, CTP biosynthetic process, cytoplasm, cytosol, deoxyribonuclease activity, DNA metabolic process, endocytosis, enzyme binding, extracellular exosome, gamma-tubulin binding, GTP binding, GTP biosynthetic process, hippocampus development, identical protein binding, intermediate filament, intermediate filament binding
Bgee · 18
NME1 → blastocyst, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, embryo, epiblast, ganglionic eminence, hippocampus proper, hypothalamus, islet of Langerhans, morula, neural tube, prefrontal cortex, primary visual cortex, proximal tubule, right frontal lobe, right kidney, superior frontal gyrus
RNA expression pattern · 18
NME1 → blastocyst, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, embryo, epiblast, ganglionic eminence, hippocampus proper, hypothalamus, islet of Langerhans, morula, neural tube, prefrontal cortex, primary visual cortex, proximal tubule, right frontal lobe, right kidney, superior frontal gyrus
related to Function · 8
NME1 → Co-transcription, Mutations, NDK, NME1-NME2, NME2, Nucleoside, This, Two
related to Interactions · 4
NME1 → Aurora, CD29NME3, Protein SET, RAR-related
Band · 2
NME1 → 11|11 D, 17q21.33
Chr. · 2
NME1 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
NME1 → 51,162,428 bp, 93,859,347 bp
2.7.11.1 · 1
NME1 → ↗
2.7.13.3 · 1
NME1 → ↗

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp kinase chr human band nucleoside diphosphate chromosome 17 enzyme 11 location mouse protein function encoded search activity 162

NME1 relationships Subject–Predicate–Object triples

TTTA extracted 133 structured relationships around NME1. Examples in this analysis include NME1 → 2.7.11.1 → ↗ and NME1 → Aliases → NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1, NME/NM23 nucleoside diphosphate kinase 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NME12.7.11.11.00infobox
NME12.7.13.31.00infobox
NME12.7.4.181.00infobox
NME12.7.4.61.00infobox
NME1AliasesNME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1, NME/NM23 nucleoside diphosphate kinase 11.00infobox
NME1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JXV, 1UCN, 2HVD, 2HVE, 3L7U, 4ENO1.00infobox
NME1Band17q21.331.00infobox
NME1Band11|11 D1.00infobox
NME1Bgeeprefrontal cortex1.00infobox
NME1Bgeehypothalamus1.00infobox
NME1BgeeBrodmann area 91.00infobox
NME1Bgeesuperior frontal gyrus1.00infobox
NME1Bgeeislet of Langerhans1.00infobox
NME1Bgeeganglionic eminence1.00infobox
NME1Bgeeright frontal lobe1.00infobox
NME1Bgeehippocampus proper1.00infobox
NME1Bgeeprimary visual cortex1.00infobox
NME1Bgeecingulate gyrus1.00infobox
NME1Bgeeright kidney1.00infobox
NME1Bgeeepiblast1.00infobox
NME1Bgeeneural tube1.00infobox
NME1Bgeeproximal tubule1.00infobox
NME1Bgeeembryo1.00infobox
NME1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
NME1Bgeemorula1.00infobox
NME1Bgeeblastocyst1.00infobox
NME1BioGPSn/a1.00infobox
NME1Chr.Chromosome 17 (human)1.00infobox
NME1Chr.Chromosome 11 (mouse)1.00infobox
NME1DatabasesNCBI: entry; OMA: entry1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around NME1 bring nearby vocabulary together. In this analysis, examples include Nucleoside, Activity and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • enzyme
    • Nucleoside
    • Activity
    • Function
    • Search
    • Nme1
    • Kinase
    • Location
    • Chromosome
    • Human
    • Also
    • Bp
    • Chr
  • gene
    • Nucleoside
    • Nme1
    • Kinase
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Activity
    • End
    • Function
    • Identified
  • aurora a kinase
    • Nucleoside
    • Nme1
    • Enzyme
    • Gene
    • Activity
    • Encoded
    • Function
    • Search
    • Location
    • Protein
    • Chromosome
    • Human
  • function
    • Activity
    • Search
    • Location
    • Also
    • Chromosome
    • Human
    • Interactions
    • Mrna
    • Nucleoside
    • Reading
    • References
    • See
  • NME1
    • Nucleoside
    • Activity
    • Function
    • Gene
    • Search
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Also
  • nme1
    • Nucleoside
    • Activity
    • Function
    • Gene
    • Search
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • Also
  • interactions
    • Reading
    • References
    • See
    • Search
    • Location
    • Human
    • Nucleoside
    • Nme1
    • Kinase
  • protein set
    • Nme2
    • Search
    • Transcript

Connections between topic areas Semantic bridges

For NME1, one of the stronger structural bridges in this analysis connects NME1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NME1Interactions · splits 8 ⟂ 9
NME1Overview · splits 13 ⟂ 4
NME1Function · splits 14 ⟂ 3

Map overview Semantic statistics

NME1

Nodes17
Edges16
Triples133
Avg. degree1.88
Density0.117647
Components1

Source & methodology

TTTA analyzes the structure around NME1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NME1 · EN edition · Analysis: TopicsToTalkAbout

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