N-Myc

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Explore the main themes, entities and connections around N-Myc. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

Interact MAX Aurora A Ubiquitin

4 related topics

Function

Transcription factors BHLH Oncogenesis

3 related topics

Clinical significance

Neuroblastomas

1 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: MYCN, MODED, N-myc, NMYC, ODED, bHLHe37, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, MYCN proto-oncogene, bHLH transcription factor, MYCNsORF, MYC…
Band: 2p24.3 · 12 A1.1|12 6.14 cM
Bgee: ventricular zone · embryo · ganglionic eminence · gonad · placenta
BioGPS: More reference expression data
Chr.: Chromosome 2 (human) · Chromosome 12 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Function

Transcription factors Transcription factor
BHLH Basic-helix-loop-helix
Oncogenesis

Clinical significance

Neuroblastomas Neuroblastoma

Interactions

Interact Protein-protein interaction
MAX MAX (gene)
Aurora A
Ubiquitin

Advanced semantic analysis

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Map overview Semantic statistics

Nodes15

Edges14

Triples122

Avg. degree1.87

Density0.133333

Components1

How this topic connects Entity context

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N-Myc

Top relations

Gene ontology · 31

N-Myc → branching morphogenesis of an epithelial tube, cartilage condensation, chromatin, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic digit morphogenesis, embryonic skeletal system morphogenesis, kinase binding, lung development, negative regulation of astrocyte differentiation, negative regulation of gene expression, negative regulation of reactive oxygen species metabolic process, nucleolus, nucleus, positive regulation of cell death, positive regulation of cell population proliferation, positive regulation of gene expression, positive regulation of mesenchymal cell proliferation

Bgee · 19

N-Myc → abdominal wall, Brodmann area 23, decidua, embryo, epiblast, ganglionic eminence, gonad, hair follicle, kidney tubule, mandibular prominence, maxillary prominence, medial ganglionic eminence, middle temporal gyrus, placenta, primitive streak, somite, superior cervical ganglion, testicle, ventricular zone

RNA expression pattern · 19

related to Function · 15

N-Myc → DNA, GSK3b, It, MYC, MYCN, MYCN/NCYM, MYCNOS, N-cym, NCYM, RNA, The MYCN, This, This NCYM, Thus NCYM, Transgenic

related to Clinical significance · 14

N-Myc → Amplification, CCND1, Excess N-Myc, H3K27ac, Interestingly, Intriguingly, MYCN, MYCN-amplified, NB, NBs, Schwann, SE-driven, SEs, Three

related to Interactions · 4

N-Myc → Aurora, Conformational, Drugs, MAX

Band · 2

N-Myc → 12 A1.1|12 6.14 cM, 2p24.3

Chr. · 2

N-Myc → Chromosome 12 (mouse), Chromosome 2 (human)

End · 2

N-Myc → 12,991,915 bp, 15,947,007 bp

Aliases · 1

N-Myc → MYCN, MODED, N-myc, NMYC, ODED, bHLHe37, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, MYCN proto-oncogene, bHLH transcription factor, MYCNsORF, MYC…

Important terminology Word statistics

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Important terminology

mycn gene human protein bp chr band also chromosome transcription cell development location function bhlh ncym mouse neuroblastoma rna dna

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
N-Myc	Aliases	MYCN, MODED, N-myc, NMYC, ODED, bHLHe37, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, MYCN proto-oncogene, bHLH transcription factor, MYCNsORF, MYC…	1.00	infobox
N-Myc	Band	2p24.3	1.00	infobox
N-Myc	Band	12 A1.1\|12 6.14 cM	1.00	infobox
N-Myc	Bgee	ventricular zone	1.00	infobox
N-Myc	Bgee	embryo	1.00	infobox
N-Myc	Bgee	ganglionic eminence	1.00	infobox
N-Myc	Bgee	gonad	1.00	infobox
N-Myc	Bgee	placenta	1.00	infobox
N-Myc	Bgee	kidney tubule	1.00	infobox
N-Myc	Bgee	testicle	1.00	infobox
N-Myc	Bgee	middle temporal gyrus	1.00	infobox
N-Myc	Bgee	decidua	1.00	infobox
N-Myc	Bgee	Brodmann area 23	1.00	infobox
N-Myc	Bgee	primitive streak	1.00	infobox
N-Myc	Bgee	epiblast	1.00	infobox
N-Myc	Bgee	hair follicle	1.00	infobox
N-Myc	Bgee	medial ganglionic eminence	1.00	infobox
N-Myc	Bgee	somite	1.00	infobox
N-Myc	Bgee	abdominal wall	1.00	infobox
N-Myc	Bgee	mandibular prominence	1.00	infobox
N-Myc	Bgee	maxillary prominence	1.00	infobox
N-Myc	Bgee	superior cervical ganglion	1.00	infobox
N-Myc	BioGPS	More reference expression data	1.00	infobox
N-Myc	Chr.	Chromosome 2 (human)	1.00	infobox
N-Myc	Chr.	Chromosome 12 (mouse)	1.00	infobox
N-Myc	Databases	NCBI: entry; OMA: entry	1.00	infobox
N-Myc	End	15,947,007 bp	1.00	infobox
N-Myc	End	12,991,915 bp	1.00	infobox
N-Myc	Ensembl	ENSG00000134323	1.00	infobox
N-Myc	Entrez	4613	1.00	infobox

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