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Targeting protein for Xklp2 is a protein that in humans is encoded by the TPX2 gene. It is one of the many spindle assembly factors that play a key role in inducing microtubule assembly and growth during M phase.
The analysis highlights Regions, Role in microtubule assembly and Key domains of TPX2 as prominent areas in the source structure around TPX2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around TPX2 shows recurring relationship patterns in the source. For example, TPX2 → activation of protein kinase activity, apoptotic process, ATP binding, axon hillock, cell cycle, cell division, cell population proliferation, cytoplasm, cytoskeleton, cytosol, GTP binding, importin-alpha family protein binding, intercellular bridge, microtubule, microtubule cytoskeleton, microtubule organizing center, mitotic cell cycle, mitotic spindle, mitotic spindle assembly, nucleoplasm Another extracted example is TPX2 → bone marrow, endothelial cell of lymphatic vessel, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, genital tubercle, gonad, left testis, oocyte, primary oocyte, primitive streak, right testis, secondary oocyte, tail of embryo, testicle, trabecular bone, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
microtubule spindle protein nucleation cell assembly cells binding human amino shown bp mitotic kinase cleavage microtubules gene aurora cancer role
TTTA extracted 178 structured relationships around TPX2. Examples in this analysis include TPX2 → Aliases → TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100, microtubule nucleation factor, TPX2 microtubule nucleation factor and TPX2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1OL5, 3E5A, 3HA6, 4C3P. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TPX2 | Aliases | TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100, microtubule nucleation factor, TPX2 microtubule nucleation factor | 1.00 | infobox |
| TPX2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1OL5, 3E5A, 3HA6, 4C3P | 1.00 | infobox |
| TPX2 | Band | 20q11.21 | 1.00 | infobox |
| TPX2 | Band | 2|2 H1 | 1.00 | infobox |
| TPX2 | Bgee | ventricular zone | 1.00 | infobox |
| TPX2 | Bgee | ganglionic eminence | 1.00 | infobox |
| TPX2 | Bgee | oocyte | 1.00 | infobox |
| TPX2 | Bgee | gonad | 1.00 | infobox |
| TPX2 | Bgee | secondary oocyte | 1.00 | infobox |
| TPX2 | Bgee | bone marrow | 1.00 | infobox |
| TPX2 | Bgee | testicle | 1.00 | infobox |
| TPX2 | Bgee | trabecular bone | 1.00 | infobox |
| TPX2 | Bgee | right testis | 1.00 | infobox |
| TPX2 | Bgee | left testis | 1.00 | infobox |
| TPX2 | Bgee | tail of embryo | 1.00 | infobox |
| TPX2 | Bgee | genital tubercle | 1.00 | infobox |
| TPX2 | Bgee | zygote | 1.00 | infobox |
| TPX2 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| TPX2 | Bgee | primitive streak | 1.00 | infobox |
| TPX2 | Bgee | epiblast | 1.00 | infobox |
| TPX2 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| TPX2 | Bgee | primary oocyte | 1.00 | infobox |
| TPX2 | BioGPS | More reference expression data | 1.00 | infobox |
| TPX2 | Chr. | Chromosome 20 (human) | 1.00 | infobox |
| TPX2 | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| TPX2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TPX2 | End | 31,801,805 bp | 1.00 | infobox |
| TPX2 | End | 152,737,241 bp | 1.00 | infobox |
| TPX2 | Ensembl | ENSG00000088325 | 1.00 | infobox |
| TPX2 | Entrez | 22974 | 1.00 | infobox |
The concept neighborhoods around TPX2 bring nearby vocabulary together. In this analysis, examples include Γ-h2ax, Dna and Tpx2's. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TPX2, one of the stronger structural bridges in this analysis connects TPX2 with Role in microtubule assembly. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TPX2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Role in microtubule assembly & Key domains of TPX2, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TPX2 · EN edition · Analysis: TopicsToTalkAbout