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Cyclin-dependent kinase 1

Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase, and is a key player in cell cycle regulation. It has been highly studied in the budding yeast S. cerevisiae, and the fission yeast S. pombe, where it is encoded by genes cdc28 and cdc2…

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12 related topics

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Regulation

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2.7.11.22
2.7.11.23
Aliases
CDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YC6, 4Y72, 5HQ0, 4YC3
Band
10q21.2 · 10 B5.3|10 36.07 cM
Bgee
ventricular zone · ganglionic eminence · trabecular bone · secondary oocyte · gonad

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Cyclin-dependent kinase 1

Nodes35
Edges34
Triples160
Avg. degree1.94
Density0.057143
Components1

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Cyclin-dependent kinase 1

Top relations

Gene ontology · 92
Cyclin-dependent kinase 1 → anaphase-promoting complex-dependent catabolic process, animal organ regeneration, apoptotic process, ATP binding, cell cycle, cell division, cell migration, cell population proliferation, cellular response to hydrogen peroxide, centrosome, centrosome cycle, chromatin binding, chromosome condensation, ciliary basal body-plasma membrane docking, cyclin B1-CDK1 complex, cyclin binding, cyclin-dependent protein kinase activity, cyclin-dependent protein kinase holoenzyme complex, cyclin-dependent protein serine/threonine kinase activity, cytoplasm
Bgee · 18
Cyclin-dependent kinase 1 → abdominal wall, appendix, bone marrow, cartilage tissue, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, mandibular prominence, maxillary prominence, medial ganglionic eminence, morula, rectum, secondary oocyte, somite, tibia, trabecular bone, ventricular zone
RNA expression pattern · 18
Cyclin-dependent kinase 1 → abdominal wall, appendix, bone marrow, cartilage tissue, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, mandibular prominence, maxillary prominence, medial ganglionic eminence, morula, rectum, secondary oocyte, somite, tibia, trabecular bone, ventricular zone
related to External links · 6
Cyclin-dependent kinase 1 → Cyclin-dependent, Overview, P06493, PDB, PDBe-KB, UniProt
Band · 2
Cyclin-dependent kinase 1 → 10 B5.3|10 36.07 cM, 10q21.2
Chr. · 2
Cyclin-dependent kinase 1 → Chromosome 10 (human), Chromosome 10 (mouse)
End · 2
Cyclin-dependent kinase 1 → 60,794,852 bp, 69,188,768 bp
2.7.11.22 · 1
Cyclin-dependent kinase 1 → ↗
2.7.11.23 · 1
Cyclin-dependent kinase 1 → ↗
Aliases · 1
Cyclin-dependent kinase 1 → CDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 1

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Important terminology

cdk1 cyclin activity phosphorylation cell cycle human cyclins leads kinase yeast bp complexes sic1 protein chr band cyclin-dependent also binding

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cyclin-dependent kinase 12.7.11.221.00infobox
Cyclin-dependent kinase 12.7.11.231.00infobox
Cyclin-dependent kinase 1AliasesCDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 11.00infobox
Cyclin-dependent kinase 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YC6, 4Y72, 5HQ0, 4YC31.00infobox
Cyclin-dependent kinase 1Band10q21.21.00infobox
Cyclin-dependent kinase 1Band10 B5.3|10 36.07 cM1.00infobox
Cyclin-dependent kinase 1Bgeeventricular zone1.00infobox
Cyclin-dependent kinase 1Bgeeganglionic eminence1.00infobox
Cyclin-dependent kinase 1Bgeetrabecular bone1.00infobox
Cyclin-dependent kinase 1Bgeesecondary oocyte1.00infobox
Cyclin-dependent kinase 1Bgeegonad1.00infobox
Cyclin-dependent kinase 1Bgeerectum1.00infobox
Cyclin-dependent kinase 1Bgeebone marrow1.00infobox
Cyclin-dependent kinase 1Bgeetibia1.00infobox
Cyclin-dependent kinase 1Bgeeappendix1.00infobox
Cyclin-dependent kinase 1Bgeecartilage tissue1.00infobox
Cyclin-dependent kinase 1Bgeemaxillary prominence1.00infobox
Cyclin-dependent kinase 1Bgeemandibular prominence1.00infobox
Cyclin-dependent kinase 1Bgeemorula1.00infobox
Cyclin-dependent kinase 1Bgeefetal liver hematopoietic progenitor cell1.00infobox
Cyclin-dependent kinase 1Bgeeepiblast1.00infobox
Cyclin-dependent kinase 1Bgeemedial ganglionic eminence1.00infobox
Cyclin-dependent kinase 1Bgeeabdominal wall1.00infobox
Cyclin-dependent kinase 1Bgeesomite1.00infobox
Cyclin-dependent kinase 1BioGPSMore reference expression data1.00infobox
Cyclin-dependent kinase 1Chr.Chromosome 10 (human)1.00infobox
Cyclin-dependent kinase 1Chr.Chromosome 10 (mouse)1.00infobox
Cyclin-dependent kinase 1DatabasesNCBI: entry; OMA: entry1.00infobox
Cyclin-dependent kinase 1End60,794,852 bp1.00infobox
Cyclin-dependent kinase 1End69,188,768 bp1.00infobox

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