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Bumetanide

Bumetanide, sold under the brand name Bumex among others, is a medication used to treat swelling and high blood pressure. This includes swelling as a result of heart failure, liver failure, or kidney problems. It may work for swelling when other medications have not. For high blood pressure it is not a preferred treatment. It is taken by mouth, or by…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C03CA02 (WHO)
Bioavailability
Almost complete (~80%)
CAS Number
28395-03-1 Y
ChEBI
CHEBI:3213 Y

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Pharmacology

Synthesis

Society and culture

Research

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Map overview Semantic statistics

Bumetanide

Nodes42
Edges41
Triples58
Avg. degree1.95
Density0.047619
Components1

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Bumetanide

Top relations

related to External links · 7
Bumetanide → Archived, Drug Information Portal, January, May, Medicine, National Library, Repurposed
related to Research · 5
Bumetanide → GABA, GABA-targeted, In, NKCC1, The
related to Society and culture · 5
Bumetanide → Drug Administration, It, National Football League, StarCaps, United States Food
has effect · 4
Bumetanide → Common, In, Other, Safety
related to Synthesis · 4
Bumetanide → Finally, In, Reacting, Reduction
Legal status · 3
Bumetanide → AU: S4 (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Pharmacodynamics · 3
Bumetanide → About, It, The
3D model (JSmol) · 1
Bumetanide → Interactive image
AHFS/Drugs.com · 1
Bumetanide → Monograph
ATC code · 1
Bumetanide → C03CA02 (WHO)

Important terminology Word statistics

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Important terminology

blood effects swelling pressure may treatment kidney side muscle medication acid high problems include low pregnancy drug sodium liver mouth

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Bumetanide3D model (JSmol)Interactive image1.00infobox
BumetanideAHFS/Drugs.comMonograph1.00infobox
BumetanideATC codeC03CA02 (WHO)1.00infobox
BumetanideBioavailabilityAlmost complete (~80%)1.00infobox
BumetanideCAS Number28395-03-1 Y1.00infobox
BumetanideChEBICHEBI:3213 Y1.00infobox
BumetanideChEMBLChEMBL1072 Y1.00infobox
BumetanideChemSpider2377 Y1.00infobox
BumetanideCompTox Dashboard (EPA)DTXSID50226991.00infobox
BumetanideDrugBankDB00887 Y1.00infobox
BumetanideECHA InfoCard100.044.5341.00infobox
BumetanideElimination half-life~0.8 hours1.00infobox
BumetanideExcretionKidney1.00infobox
BumetanideFormulaC17H20N2O5S1.00infobox
BumetanideIUPHAR/BPS48371.00infobox
BumetanideKEGGD00247 Y1.00infobox
BumetanideLegal statusAU: S4 (Prescription only)1.00infobox
BumetanideLegal statusUK: POM (Prescription only)1.00infobox
BumetanideLegal statusUS: ℞-only1.00infobox
BumetanideLicense dataUS DailyMed: Bumetanide1.00infobox
BumetanideMedlinePlusa6840511.00infobox
BumetanideMetabolismLiver1.00infobox
BumetanideMolar mass364.42 g·mol−11.00infobox
BumetanidePregnancy categoryAU: B31.00infobox
BumetanideProtein binding97%1.00infobox
BumetanidePubChem CID24711.00infobox
BumetanideRoutes of administrationBy mouth, intravenous, intramuscular, intranasal1.00infobox
BumetanideTrade namesBumex, Burinex, Enbumyst others1.00infobox
BumetanideUNII0Y2S3XUQ5H1.00infobox
Bumetanideis aloop diuretic and works by decreasing the reabsorption of sodium by the kidneys.Bumetanide was patented in 1968 and came into medical use in 19720.90text

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