Research any topic before you write.

Find related topics.Discover entities.See connections.Build a topical map.

Resistin

Resistin, also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1), is a cysteine-rich peptide hormone that is derived from adipose tissue and, in humans, is encoded by the RETN gene.

[EN, English, English]

Clinical significance, Discovery and structure & Function

Interactive map loads when it comes into view.
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Resistin. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1, resistin
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LV6
Band
19p13.2 · 8 A1.1|8 1.92 cM
Bgee
bone marrow · bone marrow cell · monocyte · trabecular bone · granulocyte
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 8 (mouse)

Topics to explore

A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Discovery and structure

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

Resistin

Nodes64
Edges63
Triples146
Avg. degree1.97
Density0.03125
Components1

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

See the strongest relationship patterns around the current topic before diving into the raw triples.

Resistin

Top relations

Gene ontology · 21
Resistin → ageing, azurophil granule lumen, biological process, extracellular exosome, extracellular region, extracellular space, fat cell differentiation, hormone activity, negative regulation of feeding behavior, neutrophil degranulation, nucleus, positive regulation of collagen metabolic process, positive regulation of progesterone secretion, positive regulation of smooth muscle cell migration, positive regulation of smooth muscle cell proliferation, positive regulation of synaptic transmission, regulation of signaling receptor activity, response to insulin, response to mechanical stimulus, signal transduction
Bgee · 20
Resistin → ankle joint, blood, bone marrow, bone marrow cell, brown adipose tissue, gastric mucosa, granulocyte, intercostal muscle, lactiferous gland, mesenteric lymph nodes, monocyte, right lung, skin of abdomen, spleen, subcutaneous adipose tissue, trabecular bone, tunica adventitia of aorta, tunica media of zone of aorta, upper lobe of left lung, white adipose tissue
RNA expression pattern · 20
Resistin → ankle joint, blood, bone marrow, bone marrow cell, brown adipose tissue, gastric mucosa, granulocyte, intercostal muscle, lactiferous gland, mesenteric lymph nodes, monocyte, right lung, skin of abdomen, spleen, subcutaneous adipose tissue, trabecular bone, tunica adventitia of aorta, tunica media of zone of aorta, upper lobe of left lung, white adipose tissue
related to Inflammation · 14
Resistin → Beyond, During, IL-12, IL-6, Interleukin-12, It, Likewise, NF-κB-mediated, One, ROS, TNF-α, Together, Toll-like, VCAM1
related to Function · 11
Resistin → Beyond, CAP1, IL-1β, IL-6, In, LPS, NETs, Notably, This, TLR4, TNF-α
related to Discovery and structure · 9
Resistin → C-terminal, Each, In, N-terminal, Specifically, Subsequent, The, These, This
related to Obesity and insulin resistance · 9
Resistin → Although, Conversely, If, Much, On, Several, Specifically, T2DM, This
related to External links · 3
Resistin → Medicine Medical Subject Headings, MeSH, National Library
Band · 2
Resistin → 19p13.2, 8 A1.1|8 1.92 cM
Chr. · 2
Resistin → Chromosome 19 (human), Chromosome 8 (mouse)

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

insulin levels hormone inflammation human bp obesity resistance adipose also tissue chr band gene t2dm chromosome 19 retn serum humans

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
ResistinAliasesRETN, ADSF, FIZZ3, RETN1, RSTN, XCP1, resistin1.00infobox
ResistinAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LV61.00infobox
ResistinBand19p13.21.00infobox
ResistinBand8 A1.1|8 1.92 cM1.00infobox
ResistinBgeebone marrow1.00infobox
ResistinBgeebone marrow cell1.00infobox
ResistinBgeemonocyte1.00infobox
ResistinBgeetrabecular bone1.00infobox
ResistinBgeegranulocyte1.00infobox
ResistinBgeeright lung1.00infobox
ResistinBgeeupper lobe of left lung1.00infobox
ResistinBgeeblood1.00infobox
ResistinBgeespleen1.00infobox
ResistinBgeegastric mucosa1.00infobox
ResistinBgeewhite adipose tissue1.00infobox
ResistinBgeesubcutaneous adipose tissue1.00infobox
ResistinBgeetunica adventitia of aorta1.00infobox
ResistinBgeelactiferous gland1.00infobox
ResistinBgeeintercostal muscle1.00infobox
ResistinBgeetunica media of zone of aorta1.00infobox
ResistinBgeemesenteric lymph nodes1.00infobox
ResistinBgeebrown adipose tissue1.00infobox
ResistinBgeeankle joint1.00infobox
ResistinBgeeskin of abdomen1.00infobox
ResistinBioGPSMore reference expression data1.00infobox
ResistinChr.Chromosome 19 (human)1.00infobox
ResistinChr.Chromosome 8 (mouse)1.00infobox
ResistinDatabasesNCBI: entry; OMA: entry1.00infobox
ResistinEnd7,670,455 bp1.00infobox
ResistinEnd3,710,110 bp1.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.