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Actinin

Actinin is a microfilament protein. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinates contractions between sarcomeres in the horizontal axis. Alpha-actinin is a part of the spectrin superfamily. This superfamily is made of spectrin, dystrophin, and their homologous and…

Art, Evolution & Cancer

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Evolution

Cancer

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Map overview Semantic statistics

Actinin

Nodes21
Edges20
Triples75
Avg. degree1.9
Density0.095238
Components1

How this topic connects Entity context

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Actinin

Top relations

related to Actin binding domain · 18
Actinin → ABD, ABDs, Alpha-actinin, C-terminal, CH, CH1, CH2, Helices, However, In, N-terminal, NMR, The, The ABD, The CH1-CH2, These, This, With
related to Structure · 16
Actinin → ABD, ACTN1, ACTN2, ACTN3, ACTN4, At, C-terminal, CaM, CH, EF-hand, It, N-terminus, SR, The, These, This
related to Cancer · 13
Actinin → ACTN4, Additionally, Alpha-actinin, Amoeboid, Changing, ECM, FSGS, II, In, It, Mutations, The, This
related to Evolution · 13
Actinin → ACTN1, ACTN2, ACTN3, Alpha-actinin, Alpha-actinin-1, Examining, II, In, Simultaneously, Some, There, This, Z-lines
related to Metabolism · 10
Actinin → ACTN3, Alpha-actinin, Among, Even, In, R577X, The, The R577X, This, XX
related to External links · 3
Actinin → Medicine Medical Subject Headings, MeSH, National Library
is a · 2
Actinin → microfilament protein, part of the spectrin superfamily

Important terminology Word statistics

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Important terminology

actin alpha-actinin muscle filaments spectrin domain actn3 binding actn4 cells protein found type four superfamily dimer actn2 repeats fibers abd

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Actininis amicrofilament protein0.90text
Actininis apart of the spectrin superfamily0.90text
Actininrelated to Actin binding domainAlpha-actinin0.60section
Actininrelated to Actin binding domainThis0.60section
Actininrelated to Actin binding domainABD0.60section
Actininrelated to Actin binding domainCH0.60section
Actininrelated to Actin binding domainCH10.60section
Actininrelated to Actin binding domainCH20.60section
Actininrelated to Actin binding domainThe CH1-CH20.60section
Actininrelated to Actin binding domainThe0.60section
Actininrelated to Actin binding domainHelices0.60section
Actininrelated to Actin binding domainN-terminal0.60section

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    Min side: 3
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