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Tuberous sclerosis complex (TSC) is a rare, multi-system genetic disorder that causes the growth of benign tumors in various organs, including the brain, kidneys, heart, liver, eyes, lungs, and skin. Symptoms may include seizures, intellectual disability, and developmental delay.
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tsc may tsc2 symptoms disease individuals people tsc1 citation needed genetic include intellectual seizures one cell subependymal skin mutation associated
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Tuberous sclerosis | Frequency | 7 to 12 per 100,000 | 1.00 | infobox |
| Tuberous sclerosis | Other names | Tuberous sclerosis complex (TSC), Bourneville disease, Bourneville-Pringle disease | 1.00 | infobox |
| Tuberous sclerosis | Prognosis | Normal life expectancy | 1.00 | infobox |
| Tuberous sclerosis | Specialty | Neurology, medical genetics | 1.00 | infobox |
| the cortical tubers | instance of | malformed tissue | 0.80 | text |
| seizures | instance of | The effect of these on the brain leads to neurological symptoms | 0.80 | text |
| intellectual disability | instance of | The effect of these on the brain leads to neurological symptoms | 0.80 | text |
| developmental delay | instance of | The effect of these on the brain leads to neurological symptoms | 0.80 | text |
| and behavioral problems | instance of | The effect of these on the brain leads to neurological symptoms | 0.80 | text |
| radial white matter tracts hyperintense on T2WI | instance of | TSC patients can exhibit other signs consistent with abnormal neuron migration | 0.80 | text |
| heterotopic grey matter | instance of | TSC patients can exhibit other signs consistent with abnormal neuron migration | 0.80 | text |
| dyscalculia | instance of | These are often specific learning disorders | 0.80 | text |
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