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Fibrate

In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They are used for a range of metabolic disorders, mainly hypercholesterolemia (high cholesterol), and are therefore hypolipidemic agents.

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ATC code
C10AB
Biological target
PPAR
MeSH
D058607
Use
hypertriglyceridemia and hypercholesterolaemia
WebMD
MedicineNet

Topics to explore

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Overview

Medical uses

Side effects

Pharmacology

Members

Advanced semantic analysis

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Map overview Semantic statistics

Fibrate

Nodes60
Edges59
Triples34
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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Fibrate

Top relations

related to Medical uses · 18
Fibrate → A1, Accumulating, Apo A1, As, ATP, Clinical, Consequently, Fewer, Fibrates, HDL, HDL-C, In, LDL, LDL-C, LDL-cholesterol, PPAR, TG, VLDL
has effect · 5
Fibrate → CPK, Fibrates, In, Most, The
related to Pharmacology · 5
Fibrate → Activating PPARs, Although, PPARs, PPARα, The PPARs
ATC code · 1
Fibrate → C10AB
Biological target · 1
Fibrate → PPAR
MeSH · 1
Fibrate → D058607
Use · 1
Fibrate → hypertriglyceridemia and hypercholesterolaemia
WebMD · 1
Fibrate → MedicineNet
related to Members · 1
Fibrate → Aluminium

Important terminology Word statistics

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Important terminology

fibrates statins hdl-c class cholesterol ppars levels tg used therefore fenofibrate ldl-c reduce therapy risk triglyceride statin pharmacology also hypercholesterolemia

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FibrateATC codeC10AB1.00infobox
FibrateBiological targetPPAR1.00infobox
FibrateMeSHD0586071.00infobox
FibrateUsehypertriglyceridemia and hypercholesterolaemia1.00infobox
FibrateWebMDMedicineNet1.00infobox
Fibratehas effectMost0.60section
Fibratehas effectCPK0.60section
Fibratehas effectFibrates0.60section
Fibratehas effectIn0.60section
Fibratehas effectThe0.60section
Fibraterelated to Medical usesFibrates0.60section
Fibraterelated to Medical usesHDL-C0.60section

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    Min side: 3
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