Serum response factor

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Explore the main themes, entities and connections around Serum response factor. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

MADS Response element Promoter Immediate early genes C-fos

16 related topics

Interactions

Interact ASCC3 ATF6 CEBPB CREB-binding protein

15 related topics

Clinical significance

Psoriasis

1 related topics

Overview

Transcription factor protein

1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: SRF, MCM1, serum response factor
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HBX, 1K6O, 1SRS
Band: 6p21.1 · 17|17 C
Bgee: muscle layer of sigmoid colon · left uterine tube · popliteal artery · tibial arteries · right coronary artery
BioGPS: More reference expression data
Chr.: Chromosome 6 (human) · Chromosome 17 (mouse)

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Interactions

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Map overview Semantic statistics

Nodes38

Edges37

Triples193

Avg. degree1.95

Density0.052632

Components1

How this topic connects Entity context

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Serum response factor

Top relations

Gene ontology · 103

Serum response factor → actin cytoskeleton organization, actin filament organization, angiogenesis involved in wound healing, associative learning, bicellular tight junction assembly, branching involved in blood vessel morphogenesis, bronchus cartilage development, cardiac myofibril assembly, cardiac vascular smooth muscle cell differentiation, cell migration involved in sprouting angiogenesis, cell-cell adhesion, cell-matrix adhesion, cellular response to glucose stimulus, cellular senescence, chromatin binding, chromatin DNA binding, cis-regulatory region sequence-specific DNA binding, contractile actin filament bundle assembly, cytoplasm, development of the heart

Bgee · 20

Serum response factor → body of uterus, dentate gyrus of hippocampal formation granule cell, gastric mucosa, genital tubercle, granulocyte, left uterine tube, lip, muscle layer of sigmoid colon, muscle of thigh, popliteal artery, primary visual cortex, right auricle of heart, right coronary artery, saphenous vein, skeletal muscle tissue, superior frontal gyrus, tail of embryo, thoracic aorta, tibial arteries, zygote

RNA expression pattern · 20

related to Function · 13

Serum response factor → Agamous, Deficiens, Elk-1, In, Interaction, MADS, MAPK, MCM1, Serum, SRE, SRF, TCFs, This

related to Interactions · 13

Serum response factor → ASCC3, ATF6, CEBPB, CREB-binding, ELK4, GATA4, GTF2F1, GTF2I, Myogenin, NFYA, Nuclear, Promyelocytic, Serum

Band · 2

Serum response factor → 17|17 C, 6p21.1

Chr. · 2

Serum response factor → Chromosome 17 (mouse), Chromosome 6 (human)

End · 2

Serum response factor → 43,181,506 bp, 46,867,101 bp

Aliases · 1

Serum response factor → SRF, MCM1, serum response factor

Available structures · 1

Serum response factor → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HBX, 1K6O, 1SRS

Important terminology Word statistics

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Important terminology

srf serum response bp factor protein chr human band chromosome growth gene muscle transcription location also mouse regulation function external

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Serum response factor	Aliases	SRF, MCM1, serum response factor	1.00	infobox
Serum response factor	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HBX, 1K6O, 1SRS	1.00	infobox
Serum response factor	Band	6p21.1	1.00	infobox
Serum response factor	Band	17\|17 C	1.00	infobox
Serum response factor	Bgee	muscle layer of sigmoid colon	1.00	infobox
Serum response factor	Bgee	left uterine tube	1.00	infobox
Serum response factor	Bgee	popliteal artery	1.00	infobox
Serum response factor	Bgee	tibial arteries	1.00	infobox
Serum response factor	Bgee	right coronary artery	1.00	infobox
Serum response factor	Bgee	saphenous vein	1.00	infobox
Serum response factor	Bgee	body of uterus	1.00	infobox
Serum response factor	Bgee	right auricle of heart	1.00	infobox
Serum response factor	Bgee	gastric mucosa	1.00	infobox
Serum response factor	Bgee	thoracic aorta	1.00	infobox
Serum response factor	Bgee	tail of embryo	1.00	infobox
Serum response factor	Bgee	genital tubercle	1.00	infobox
Serum response factor	Bgee	zygote	1.00	infobox
Serum response factor	Bgee	muscle of thigh	1.00	infobox
Serum response factor	Bgee	lip	1.00	infobox
Serum response factor	Bgee	superior frontal gyrus	1.00	infobox
Serum response factor	Bgee	granulocyte	1.00	infobox
Serum response factor	Bgee	primary visual cortex	1.00	infobox
Serum response factor	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Serum response factor	Bgee	skeletal muscle tissue	1.00	infobox
Serum response factor	BioGPS	More reference expression data	1.00	infobox
Serum response factor	Chr.	Chromosome 6 (human)	1.00	infobox
Serum response factor	Chr.	Chromosome 17 (mouse)	1.00	infobox
Serum response factor	Databases	NCBI: entry; OMA: entry	1.00	infobox
Serum response factor	End	43,181,506 bp	1.00	infobox
Serum response factor	End	46,867,101 bp	1.00	infobox

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Min side: 3