Tyrosine-protein kinase CSK

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Explore the main themes, entities and connections around Tyrosine-protein kinase CSK. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Role in development and regulation

Signal transduction Adherens junction Morphogenesis Bone resorption ERK1

15 related topics

Function

Cell growth Migration Immune response Phosphorylation Kinases

8 related topics

Mutations

PRKACA Protein kinase A

2 related topics

Clinical significance

PTPN22 Autoimmune diseases

2 related topics

Key facts & relationships

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2.7.10.4: ↗
Aliases: CSK, Src, c-src tyrosine kinase, CSK/Src, non-receptor tyrosine kinase, C-terminal Src kinase
Available structures: Available structuresPDBOrtholog search: H3BU69 PDBe H3BU69 RCSB List of PDB id codes1BYG, 1CSK, 3D7T, 3D7U, 3EAC, 3EAZ
Band: 15q24.1 · 9 B|9 31.18 cM
Bgee: granulocyte · monocyte · spleen · blood · lymph node
BioGPS: More reference expression data

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Overview

Enzyme
Gene
Tyrosine
C-terminal
Src-family kinases Src-family kinase
SRC Proto-oncogene tyrosine-protein kinase Src
HCK
FYN
LCK
LYN
YES1

Function

Role in development and regulation

Mutations

Clinical significance

PTPN22
Autoimmune diseases Autoimmune disease

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Map overview Semantic statistics

Nodes44

Edges43

Triples120

Avg. degree1.95

Density0.045455

Components1

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Tyrosine-protein kinase CSK

Top relations

Gene ontology · 53

Tyrosine-protein kinase CSK → adaptive immune response, adherens junction organization, ATP binding, brain development, cell differentiation, cell-cell junction, cellular response to peptide hormone stimulus, central nervous system development, cytoplasm, cytosol, epidermal growth factor receptor signaling pathway, extracellular exosome, extrinsic component of cytoplasmic side of plasma membrane, identical protein binding, immune system process, innate immune response, kinase activity, membrane, membrane raft, metal ion binding

Bgee · 17

Tyrosine-protein kinase CSK → appendix, blood, bone marrow cell, gastrula, granulocyte, lip, lymph node, mesenteric lymph nodes, monocyte, mucosa of transverse colon, neural layer of retina, spleen, stromal cell of endometrium, thymus, tonsil, ventricular zone, yolk sac

RNA expression pattern · 17

related to Role in development and regulation · 8

Tyrosine-protein kinase CSK → Adherens, CSK, ERK1, ERK2, Fc, Golgi, MAP, Tyrosine-protein

Band · 2

Tyrosine-protein kinase CSK → 15q24.1, 9 B|9 31.18 cM

Chr. · 2

Tyrosine-protein kinase CSK → Chromosome 15 (human), Chromosome 9 (mouse)

End · 2

Tyrosine-protein kinase CSK → 57,560,914 bp, 74,803,198 bp

2.7.10.4 · 1

Tyrosine-protein kinase CSK → ↗

Aliases · 1

Tyrosine-protein kinase CSK → CSK, Src, c-src tyrosine kinase, CSK/Src, non-receptor tyrosine kinase, C-terminal Src kinase

Available structures · 1

Tyrosine-protein kinase CSK → Available structuresPDBOrtholog search: H3BU69 PDBe H3BU69 RCSB List of PDB id codes1BYG, 1CSK, 3D7T, 3D7U, 3EAC, 3EAZ

Important terminology Word statistics

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Important terminology

csk kinase bp gene chr human band c-terminal src phosphorylation location enzyme activity chromosome 15 tyrosine regulation tyrosine-protein end kinases

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Tyrosine-protein kinase CSK	2.7.10.4	↗	1.00	infobox
Tyrosine-protein kinase CSK	Aliases	CSK, Src, c-src tyrosine kinase, CSK/Src, non-receptor tyrosine kinase, C-terminal Src kinase	1.00	infobox
Tyrosine-protein kinase CSK	Available structures	Available structuresPDBOrtholog search: H3BU69 PDBe H3BU69 RCSB List of PDB id codes1BYG, 1CSK, 3D7T, 3D7U, 3EAC, 3EAZ	1.00	infobox
Tyrosine-protein kinase CSK	Band	15q24.1	1.00	infobox
Tyrosine-protein kinase CSK	Band	9 B\|9 31.18 cM	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	granulocyte	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	monocyte	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	spleen	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	blood	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	lymph node	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	appendix	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	mucosa of transverse colon	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	tonsil	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	bone marrow cell	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	stromal cell of endometrium	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	mesenteric lymph nodes	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	thymus	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	neural layer of retina	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	lip	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	ventricular zone	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	yolk sac	1.00	infobox
Tyrosine-protein kinase CSK	Bgee	gastrula	1.00	infobox
Tyrosine-protein kinase CSK	BioGPS	More reference expression data	1.00	infobox
Tyrosine-protein kinase CSK	Chr.	Chromosome 15 (human)	1.00	infobox
Tyrosine-protein kinase CSK	Chr.	Chromosome 9 (mouse)	1.00	infobox
Tyrosine-protein kinase CSK	Databases	NCBI: entry; OMA: entry	1.00	infobox
Tyrosine-protein kinase CSK	End	74,803,198 bp	1.00	infobox
Tyrosine-protein kinase CSK	End	57,560,914 bp	1.00	infobox
Tyrosine-protein kinase CSK	Ensembl	ENSG00000103653	1.00	infobox
Tyrosine-protein kinase CSK	Entrez	1445	1.00	infobox

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