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Schaffer collateral

Schaffer collaterals are axon collaterals given off by CA3 pyramidal cells in the hippocampus. These collaterals project to area CA1 of the hippocampus and are an integral part of memory formation and the emotional network of the Papez circuit, and of the hippocampal trisynaptic loop. It is one of the most studied synapses in the world and named after…

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Function

Schaffer collateral and hippocampal synaptic plasticity

Vesicular release at "Schaffer Collateral"

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Map overview Semantic statistics

Schaffer collateral

Nodes95
Edges94
Triples47
Avg. degree1.98
Density0.021053
Components1

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Schaffer collateral

Top relations

related to External links · 9
Schaffer collateral → Collingridge GL, Degradation, Excitatory, Involvement, Karpova, Long-Term Potentiation, Protein Synthesis, Schaffer, Schaffer Collateral CA1 Synapses
related to Vesicular release at "Schaffer Collateral" · 9
Schaffer collateral → Additional, CA1, Multivesicular, MVR, Rate, Schaffer, These, Transmitters, Vesicles
related to Location · 6
Schaffer collateral → CA1, CA3, From, Schaffer, The, The Schaffer
related to Long-term Potentiation · 6
Schaffer collateral → CA1, CA3, Long-term, LTP, LTPs, Schaffer
related to Function · 5
Schaffer collateral → CA1, CA3, Schaffer, The, Throughout
related to Development · 4
Schaffer collateral → However, Plastic, The, The Schaffer
related to Schaffer collateral and hippocampal synaptic plasticity · 4
Schaffer collateral → Long-term Plasticity, Plastic, Schaffer, Short-term Plasticity
is a · 1
Schaffer collateral → conductor of the orchestra

Important terminology Word statistics

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Important terminology

schaffer hippocampus collateral synapses collaterals ca1 sk2 ltp ca3 memory synaptic long-term plasticity information pyramidal excitatory hippocampal potentiation changes patterns

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Schaffer collateralis aconductor of the orchestra0.90text
Alzheimer's diseaseinstance ofthe research on Schaffer collaterals may help to find treatments for diseases related to the hippocampus or its neural processing pathways0.80text
a neurodegenerative disorder.Long-term potentiationinstance ofthe research on Schaffer collaterals may help to find treatments for diseases related to the hippocampus or its neural processing pathways0.80text
glutamateinstance ofthat are filled with neurotransmitters0.80text
Schaffer collateralrelated to DevelopmentThe0.60section
Schaffer collateralrelated to DevelopmentPlastic0.60section
Schaffer collateralrelated to DevelopmentThe Schaffer0.60section
Schaffer collateralrelated to DevelopmentHowever0.60section
Schaffer collateralrelated to External linksExcitatory0.60section
Schaffer collateralrelated to External linksSchaffer0.60section
Schaffer collateralrelated to External linksCollingridge GL0.60section
Schaffer collateralrelated to External linksInvolvement0.60section

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    Min side: 3
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