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CBFB: Measurement & Overview

Core-binding factor subunit beta is a protein that in humans is encoded by the CBFB gene.

Language: English [EN]
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CBFB topic overview

The analysis highlights Measurement and Overview as prominent areas in the source structure around CBFB.

Related topics
9
Source areas
1
Connected nodes
10
Extracted relationships
99
Concept neighborhoods
6
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CBFB, PEBP2B, core-binding factor, beta subunit, core-binding factor beta subunit, core-binding factor subunit beta
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CL3, 1E50, 1H9D, 4N9F
Band
16q22.1 · 8 D3|8 53.04 cM
Bgee
secondary oocyte · sural nerve · tibia · Achilles tendon · periodontal fiber
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CBFB connects Entity context

The extracted context around CBFB shows recurring relationship patterns in the source. For example, CBFB → cell maturation, core-binding factor complex, definitive hemopoiesis, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, lymphocyte differentiation, membrane, myeloid cell differentiation, negative regulation of CD4-positive, alpha-beta T cell differentiation, negative regulation of transcription by RNA polymerase II, nucleoplasm, nucleus, ossification, osteoblast differentiation, positive regulation of CD8-positive, alpha-beta T cell differentiation, positive regulation of transcription by RNA polymerase II, protein binding, protein polyubiquitination, regulation of B cell receptor signaling pathway Another extracted example is CBFB → Achilles tendon, body of femur, bone marrow cell, calvaria, cartilage tissue, Epithelium of choroid plexus, extensor digitorum longus muscle, islet of Langerhans, periodontal fiber, plantaris muscle, quadriceps femoris muscle, secondary oocyte, sternocleidomastoid muscle, sural nerve, temporal muscle, tibia, tibialis anterior muscle, triceps brachii muscle, trigeminal ganglion, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

CBFB

Top relations

Gene ontology · 34
CBFB → cell maturation, core-binding factor complex, definitive hemopoiesis, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, lymphocyte differentiation, membrane, myeloid cell differentiation, negative regulation of CD4-positive, alpha-beta T cell differentiation, negative regulation of transcription by RNA polymerase II, nucleoplasm, nucleus, ossification, osteoblast differentiation, positive regulation of CD8-positive, alpha-beta T cell differentiation, positive regulation of transcription by RNA polymerase II, protein binding, protein polyubiquitination, regulation of B cell receptor signaling pathway
Bgee · 20
CBFB → Achilles tendon, body of femur, bone marrow cell, calvaria, cartilage tissue, Epithelium of choroid plexus, extensor digitorum longus muscle, islet of Langerhans, periodontal fiber, plantaris muscle, quadriceps femoris muscle, secondary oocyte, sternocleidomastoid muscle, sural nerve, temporal muscle, tibia, tibialis anterior muscle, triceps brachii muscle, trigeminal ganglion, vastus lateralis muscle
RNA expression pattern · 20
CBFB → Achilles tendon, body of femur, bone marrow cell, calvaria, cartilage tissue, Epithelium of choroid plexus, extensor digitorum longus muscle, islet of Langerhans, periodontal fiber, plantaris muscle, quadriceps femoris muscle, secondary oocyte, sternocleidomastoid muscle, sural nerve, temporal muscle, tibia, tibialis anterior muscle, triceps brachii muscle, trigeminal ganglion, vastus lateralis muscle
Band · 2
CBFB → 16q22.1, 8 D3|8 53.04 cM
Chr. · 2
CBFB → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
CBFB → 105,944,621 bp, 67,101,058 bp
related to External links · 2
CBFB → Human CBFB, UCSC Genome Browser
Aliases · 1
CBFB → CBFB, PEBP2B, core-binding factor, beta subunit, core-binding factor beta subunit, core-binding factor subunit beta
Available structures · 1
CBFB → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CL3, 1E50, 1H9D, 4N9F
BioGPS · 1
CBFB → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene factor chromosome 16 beta core-binding bp human chr subunit band protein cbf location binding myeloid encoded core leukemia two

CBFB relationships Subject–Predicate–Object triples

TTTA extracted 99 structured relationships around CBFB. Examples in this analysis include CBFB → Aliases → CBFB, PEBP2B, core-binding factor, beta subunit, core-binding factor beta subunit, core-binding factor subunit beta and CBFB → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CL3, 1E50, 1H9D, 4N9F. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CBFBAliasesCBFB, PEBP2B, core-binding factor, beta subunit, core-binding factor beta subunit, core-binding factor subunit beta1.00infobox
CBFBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CL3, 1E50, 1H9D, 4N9F1.00infobox
CBFBBand16q22.11.00infobox
CBFBBand8 D3|8 53.04 cM1.00infobox
CBFBBgeesecondary oocyte1.00infobox
CBFBBgeesural nerve1.00infobox
CBFBBgeetibia1.00infobox
CBFBBgeeAchilles tendon1.00infobox
CBFBBgeeperiodontal fiber1.00infobox
CBFBBgeetibialis anterior muscle1.00infobox
CBFBBgeecartilage tissue1.00infobox
CBFBBgeebone marrow cell1.00infobox
CBFBBgeeislet of Langerhans1.00infobox
CBFBBgeeEpithelium of choroid plexus1.00infobox
CBFBBgeetrigeminal ganglion1.00infobox
CBFBBgeecalvaria1.00infobox
CBFBBgeetriceps brachii muscle1.00infobox
CBFBBgeesternocleidomastoid muscle1.00infobox
CBFBBgeequadriceps femoris muscle1.00infobox
CBFBBgeeextensor digitorum longus muscle1.00infobox
CBFBBgeetemporal muscle1.00infobox
CBFBBgeevastus lateralis muscle1.00infobox
CBFBBgeeplantaris muscle1.00infobox
CBFBBgeebody of femur1.00infobox
CBFBBioGPSMore reference expression data1.00infobox
CBFBChr.Chromosome 16 (human)1.00infobox
CBFBChr.Chromosome 8 (mouse)1.00infobox
CBFBDatabasesNCBI: entry; OMA: entry1.00infobox
CBFBEnd67,101,058 bp1.00infobox
CBFBEnd105,944,621 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CBFB bring nearby vocabulary together. In this analysis, examples include Core-binding, Factor and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CBFB
    • Core-binding
    • Factor
    • Location
    • Protein
    • Gene
    • Human
    • Subunit
    • Bp
    • Chr
    • Chromosome
    • Cancer
    • Cases
  • cbfb
    • Core-binding
    • Factor
    • Location
    • Protein
    • Gene
    • Human
    • Subunit
    • Bp
    • Chr
    • Chromosome
    • Cancer
    • Cases
  • gene
    • Location
    • Protein
    • Human
    • Subunit
    • Bp
    • Chr
    • Chromosome
    • Mouse
    • Transcription
    • Binding
    • Cbf
    • Myeloid
  • transcription factor
    • Protein
    • Gene
    • Subunit
    • Core-binding
    • Chromosome
    • Complex
    • Differentiation
    • Dna
    • Encoded
    • Factor
    • Function
    • Mouse
  • protein
    • Transcription
    • Gene
    • Subunit
    • Complex
    • Differentiation
    • Dna
    • Function
    • Mouse
    • Mrna
    • Muscle
    • Receptor
    • Regulatory
  • breast cancer
    • Cases
    • Core
    • Cbf
    • Myeloid
    • Cbfb
    • Factor
    • Gene

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the CBFB map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

CBFB

Nodes11
Edges10
Triples99
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around CBFB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CBFB · EN edition · Analysis: TopicsToTalkAbout

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