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Rolling circle replication (RCR) is a process of unidirectional nucleic acid replication that can rapidly synthesize multiple copies of circular molecules of DNA or RNA, such as plasmids, the genomes of bacteriophages, and the circular RNA genome of viroids. Some eukaryotic viruses also replicate their DNA or RNA via the rolling circle mechanism.
Applications, Applications of RCA & Circular DNA replication
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dna replication rca rolling amplification circle circular used also rna strand primer template polymerase protein host strands immuno-rca ssdna reaction
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| polymerase chain reaction | instance of | Different from conventional DNA amplification techniques | 0.80 | text |
| mutations in cancer biopsies - can be detected through rolling circle amplification | instance of | such as microscopy.Detecting rare mutationsRare molecular events - | 0.80 | text |
| mutations in cancer biopsies - can be detected through rolling circle amplification | instance of | Detecting rare mutationsRare molecular events - | 0.80 | text |
| Rolling circle replication | related to Replication of viral DNA | Some DNA | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | For | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | HHV-6 | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | During | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | DNA | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | Human Papillomavirus-16 | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | HPV-16 | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | E1 | 0.60 | section |
| Rolling circle replication | related to Replication of viral DNA | In | 0.60 | section |
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