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PRDX5

Peroxiredoxin-5 (PRDX5), mitochondrial is a protein that in humans is encoded by the PRDX5 gene, located on chromosome 11.

Function, Clinical significance & Structure

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Function

12 related topics

Clinical significance

7 related topics

Structure

3 related topics

Overview

11 related topics

Key facts & relationships

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1.11.1.24
Aliases
PRDX5, ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, prx-V, SBBI10, peroxiredoxin 5
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H4O, 1HD2, 1OC3, 1URM, 2VL2, 2VL3, 2VL9, 3MNG, 4K7I, 4K7N, 4K7O, 4MMM
Band
11q13.1 · 19 A|19 5.08 cM
Bgee
bronchial epithelial cell · epithelium of nasopharynx · palpebral conjunctiva · right uterine tube · mucosa of transverse colon
BioGPS
n/a

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Overview

Structure

Function

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

PRDX5

Nodes38
Edges37
Triples138
Avg. degree1.95
Density0.052632
Components1

How this topic connects Entity context

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PRDX5

Top relations

Gene ontology · 39
PRDX5 → antioxidant activity, apoptotic process, cell redox homeostasis, cellular oxidant detoxification, cellular response to oxidative stress, cellular response to reactive oxygen species, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, cytoplasm, cytoplasmic vesicle, cytosol, extracellular exosome, extracellular space, hydrogen peroxide catabolic process, inflammatory response, intracellular membrane-bounded organelle, mitochondrial matrix, mitochondrion, NADPH oxidation, negative regulation of apoptotic process, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Bgee · 20
PRDX5 → apex of heart, bronchial epithelial cell, choroid plexus of fourth ventricle, deep cerebellar nuclei, dentate gyrus of hippocampal formation granule cell, epithelium of nasopharynx, granulocyte, human kidney, lip, medial vestibular nucleus, mucosa of transverse colon, olfactory zone of nasal mucosa, palpebral conjunctiva, right adrenal cortex, right adrenal gland, right kidney, right lobe of thyroid gland, right uterine tube, transitional epithelium of urinary bladder, vestibular membrane of cochlear duct
RNA expression pattern · 20
PRDX5 → apex of heart, bronchial epithelial cell, choroid plexus of fourth ventricle, deep cerebellar nuclei, dentate gyrus of hippocampal formation granule cell, epithelium of nasopharynx, granulocyte, human kidney, lip, medial vestibular nucleus, mucosa of transverse colon, olfactory zone of nasal mucosa, palpebral conjunctiva, right adrenal cortex, right adrenal gland, right kidney, right lobe of thyroid gland, right uterine tube, transitional epithelium of urinary bladder, vestibular membrane of cochlear duct
related to Function · 13
PRDX5 → As, CHO, Drosophila, HeLa, HT-22, In, Meanwhile, MPP, NIH3T3, Overexpression, PDGF, TNF-alpha, Xenopus
related to Interactions · 7
PRDX5 → GATA-binding, PARK7, PRDX1, PRDX2, PRDX6, SOD1, Transcription
related to Structure · 6
PRDX5 → According, C-terminal, Cys, In, N-terminal, The
related to Clinical significance · 4
PRDX5 → By, GATA1, In, Kunze
Band · 2
PRDX5 → 11q13.1, 19 A|19 5.08 cM
Chr. · 2
PRDX5 → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
PRDX5 → 6,887,474 bp, 64,321,811 bp

Important terminology Word statistics

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Important terminology

human gene antioxidant peroxiredoxin bp chromosome 11 chr band peroxide shown expression mitochondrial enzyme protein mouse oxidative location apoptosis cytosol

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PRDX51.11.1.241.00infobox
PRDX5AliasesPRDX5, ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, prx-V, SBBI10, peroxiredoxin 51.00infobox
PRDX5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1H4O, 1HD2, 1OC3, 1URM, 2VL2, 2VL3, 2VL9, 3MNG, 4K7I, 4K7N, 4K7O, 4MMM1.00infobox
PRDX5Band11q13.11.00infobox
PRDX5Band19 A|19 5.08 cM1.00infobox
PRDX5Bgeebronchial epithelial cell1.00infobox
PRDX5Bgeeepithelium of nasopharynx1.00infobox
PRDX5Bgeepalpebral conjunctiva1.00infobox
PRDX5Bgeeright uterine tube1.00infobox
PRDX5Bgeemucosa of transverse colon1.00infobox
PRDX5Bgeeapex of heart1.00infobox
PRDX5Bgeeolfactory zone of nasal mucosa1.00infobox
PRDX5Bgeeright adrenal gland1.00infobox
PRDX5Bgeeright adrenal cortex1.00infobox
PRDX5Bgeeright lobe of thyroid gland1.00infobox
PRDX5Bgeegranulocyte1.00infobox
PRDX5Bgeeright kidney1.00infobox
PRDX5Bgeehuman kidney1.00infobox
PRDX5Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
PRDX5Bgeechoroid plexus of fourth ventricle1.00infobox
PRDX5Bgeemedial vestibular nucleus1.00infobox
PRDX5Bgeevestibular membrane of cochlear duct1.00infobox
PRDX5Bgeelip1.00infobox
PRDX5Bgeedeep cerebellar nuclei1.00infobox
PRDX5Bgeetransitional epithelium of urinary bladder1.00infobox
PRDX5BioGPSn/a1.00infobox
PRDX5Chr.Chromosome 11 (human)1.00infobox
PRDX5Chr.Chromosome 19 (mouse)1.00infobox
PRDX5DatabasesNCBI: entry; OMA: entry1.00infobox
PRDX5End64,321,811 bp1.00infobox

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