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PCNT

Pericentrin (kendrin), also known as PCNT and pericentrin-B (PCNTB), is a protein which in humans is encoded by the PCNT gene on chromosome 21. This protein localizes to the centrosome and recruits proteins to the pericentriolar matrix (PCM) to ensure proper centrosome and mitotic spindle formation, and thus, uninterrupted cell cycle progression. This…

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Aliases
PCNT, KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4, pericentrin
Band
21q22.3 · 10|10 C1
Bgee
gastrocnemius muscle · body of tongue · muscle of thigh · thoracic diaphragm · Skeletal muscle tissue of rectus abdominis
BioGPS
More reference expression data
Chr.
Chromosome 21 (human) · Chromosome 10 (mouse)
Databases
NCBI: entry; OMA: entry

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Map overview Semantic statistics

PCNT

Nodes77
Edges76
Triples113
Avg. degree1.97
Density0.025974
Components1

How this topic connects Entity context

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PCNT

Top relations

Gene ontology · 20
PCNT → calmodulin binding, centriolar satellite, centriole, centrosome, ciliary basal body-plasma membrane docking, cilium assembly, cytoplasm, cytoskeleton, cytosol, G2/M transition of mitotic cell cycle, membrane, microtubule, microtubule cytoskeleton organization, microtubule organizing center, mitotic spindle organization, molecular adaptor activity, positive regulation of intracellular protein transport, protein binding, regulation of G2/M transition of mitotic cell cycle, signal transduction
Bgee · 19
PCNT → ascending aorta, biceps brachii, body of tongue, extraocular muscle, foot, gastrocnemius muscle, glutes, hand, interventricular septum, middle temporal gyrus, muscle of thigh, primary oocyte, secondary oocyte, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, thoracic diaphragm, triceps brachii muscle, zygote
RNA expression pattern · 19
PCNT → ascending aorta, biceps brachii, body of tongue, extraocular muscle, foot, gastrocnemius muscle, glutes, hand, interventricular septum, middle temporal gyrus, muscle of thigh, primary oocyte, secondary oocyte, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, thoracic diaphragm, triceps brachii muscle, zygote
related to Structure · 12
PCNT → As, C-terminus, CEP215, CPM, However, In, Li, PACT, PCM, PCNTB, The N-terminus, The PACT
related to Function · 11
PCNT → CEP215, DISC1, Downregulation, G2/M, In, It, Moreover, PCM, PLK1, The, This
related to Clinical significance · 8
PCNT → Additionally, CML, Down, DS, In, MOPDII, Mutations, Seckel
related to Interactions · 3
PCNT → CEP215, CHD3/4, DISC1
Band · 2
PCNT → 10|10 C1, 21q22.3
Chr. · 2
PCNT → Chromosome 10 (mouse), Chromosome 21 (human)
End · 2
PCNT → 46,445,769 bp, 76,278,620 bp

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Important terminology

protein gene chromosome centrosome bp 21 cell chr human band microtubule pcntb centriole mitotic spindle cycle c-terminus also proteins pcm

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PCNTAliasesPCNT, KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4, pericentrin1.00infobox
PCNTBand21q22.31.00infobox
PCNTBand10|10 C11.00infobox
PCNTBgeegastrocnemius muscle1.00infobox
PCNTBgeebody of tongue1.00infobox
PCNTBgeemuscle of thigh1.00infobox
PCNTBgeethoracic diaphragm1.00infobox
PCNTBgeeSkeletal muscle tissue of rectus abdominis1.00infobox
PCNTBgeeglutes1.00infobox
PCNTBgeetriceps brachii muscle1.00infobox
PCNTBgeebiceps brachii1.00infobox
PCNTBgeeSkeletal muscle tissue of biceps brachii1.00infobox
PCNTBgeemiddle temporal gyrus1.00infobox
PCNTBgeeprimary oocyte1.00infobox
PCNTBgeezygote1.00infobox
PCNTBgeeinterventricular septum1.00infobox
PCNTBgeesecondary oocyte1.00infobox
PCNTBgeesoleus muscle1.00infobox
PCNTBgeehand1.00infobox
PCNTBgeefoot1.00infobox
PCNTBgeeextraocular muscle1.00infobox
PCNTBgeeascending aorta1.00infobox
PCNTBioGPSMore reference expression data1.00infobox
PCNTChr.Chromosome 21 (human)1.00infobox
PCNTChr.Chromosome 10 (mouse)1.00infobox
PCNTDatabasesNCBI: entry; OMA: entry1.00infobox
PCNTEnd46,445,769 bp1.00infobox
PCNTEnd76,278,620 bp1.00infobox
PCNTEnsemblENSG000001602991.00infobox
PCNTEntrez51161.00infobox

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