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PCM1: Gene, Function & Clinical significance

Pericentriolar material 1, also known as PCM1, is a protein which in humans is encoded by the PCM1 gene.

Language: English [EN]
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PCM1 topic overview

The analysis highlights Gene, Function and Clinical significance as prominent areas in the source structure around PCM1.

Related topics
27
Source areas
6
Connected nodes
33
Extracted relationships
96
Concept neighborhoods
12
Bridge connections
33

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Gene · 11 topics
Function · 7 topics
Clinical significance · 4 topics
Overview · 2 topics
Tissue distribution · 2 topics
Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PCM1, PTC4, RET/PCM-1, pericentriolar material 1
Band
8 A4|8 23.89 cM
Bgee
spermatocyte · genital tubercle · tail of embryo · saccule · ventricular zone
BioGPS
More reference expression data
Chr.
Chromosome 8 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene

Tissue distribution

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PCM1 connects Entity context

The extracted context around PCM1 shows recurring relationship patterns in the source. For example, PCM1 → apical part of cell, cell projection, cell projection organization, centriolar satellite, centriole, centrosome, centrosome cycle, ciliary basal body, ciliary basal body-plasma membrane docking, ciliary transition zone, cilium assembly, cytoplasm, cytoplasmic microtubule organization, cytoskeleton, cytosol, G2/M transition of mitotic cell cycle, identical protein binding, interkinetic nuclear migration, intraciliary transport involved in cilium assembly, membrane Another extracted example is PCM1 → ascending aorta, genital tubercle, otic placode, otic vesicle, saccule, spermatid, spermatocyte, tail of embryo, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

PCM1

Top relations

Gene ontology · 37
PCM1 → apical part of cell, cell projection, cell projection organization, centriolar satellite, centriole, centrosome, centrosome cycle, ciliary basal body, ciliary basal body-plasma membrane docking, ciliary transition zone, cilium assembly, cytoplasm, cytoplasmic microtubule organization, cytoskeleton, cytosol, G2/M transition of mitotic cell cycle, identical protein binding, interkinetic nuclear migration, intraciliary transport involved in cilium assembly, membrane
Bgee · 10
PCM1 → ascending aorta, genital tubercle, otic placode, otic vesicle, saccule, spermatid, spermatocyte, tail of embryo, ventricular zone, zygote
RNA expression pattern · 10
PCM1 → ascending aorta, genital tubercle, otic placode, otic vesicle, saccule, spermatid, spermatocyte, tail of embryo, ventricular zone, zygote
related to Clinical significance · 8
PCM1 → Bardet-Biedl, BBS4, DISC1, England, If, Mutations, Scotland, This
related to Function · 7
PCM1 → As, Dissociation, Immunolabeling, Targeting, The, The PCM1, These
related to Gene · 5
PCM1 → ABCA2, ATP, ATPbinding, GTPase, The
related to Tissue distribution · 2
PCM1 → CNS, In
Aliases · 1
PCM1 → PCM1, PTC4, RET/PCM-1, pericentriolar material 1
Band · 1
PCM1 → 8 A4|8 23.89 cM
BioGPS · 1
PCM1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene found centrosome cell bp schizophrenia also pericentriolar material mouse complex chr band expression function shown known humans location

PCM1 relationships Subject–Predicate–Object triples

TTTA extracted 96 structured relationships around PCM1. Examples in this analysis include PCM1 → Aliases → PCM1, PTC4, RET/PCM-1, pericentriolar material 1 and PCM1 → Band → 8 A4|8 23.89 cM. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PCM1AliasesPCM1, PTC4, RET/PCM-1, pericentriolar material 11.00infobox
PCM1Band8 A4|8 23.89 cM1.00infobox
PCM1Bgeespermatocyte1.00infobox
PCM1Bgeegenital tubercle1.00infobox
PCM1Bgeetail of embryo1.00infobox
PCM1Bgeesaccule1.00infobox
PCM1Bgeeventricular zone1.00infobox
PCM1Bgeespermatid1.00infobox
PCM1Bgeeotic placode1.00infobox
PCM1Bgeeascending aorta1.00infobox
PCM1Bgeezygote1.00infobox
PCM1Bgeeotic vesicle1.00infobox
PCM1BioGPSMore reference expression data1.00infobox
PCM1Chr.Chromosome 8 (mouse)1.00infobox
PCM1DatabasesNCBI: entry; OMA: entry1.00infobox
PCM1End41,332,344 bp1.00infobox
PCM1EnsemblENSG000000786741.00infobox
PCM1Entrez51081.00infobox
PCM1External IDsOMIM: 600299; MGI: 1277958; GeneCards: PCM11.00infobox
PCM1Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 8 (mouse)Band8 A4|8 23.89 cMStart41,239,752 bpEnd41,332,344 bp1.00infobox
PCM1Gene ontologyprotein binding1.00infobox
PCM1Gene ontologyidentical protein binding1.00infobox
PCM1Gene ontologyciliary basal body1.00infobox
PCM1Gene ontologycell projection1.00infobox
PCM1Gene ontologynuclear membrane1.00infobox
PCM1Gene ontologymembrane1.00infobox
PCM1Gene ontologymicrotubule organizing center1.00infobox
PCM1Gene ontologycentriole1.00infobox
PCM1Gene ontologycytoskeleton1.00infobox
PCM1Gene ontologyciliary transition zone1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PCM1 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Cell. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PCM1
    • Protein
    • Gene
    • Cell
    • Found
    • Mouse
    • Pericentriolar
    • Shown
    • Centrosome
    • Complex
    • Schizophrenia
    • A4
    • Centriolar
  • pcm1
    • Protein
    • Gene
    • Cell
    • Found
    • Mouse
    • Pericentriolar
    • Shown
    • Centrosome
    • Complex
    • Schizophrenia
    • A4
    • Centriolar
  • gene
    • Material
    • Pericentriolar
    • A4
    • Chromosome
    • Function
    • Known
    • Location
    • Bp
    • Chr
    • Mouse
    • Pcm1
    • Protein
  • cell cycle
    • Centrosome
    • Complex
    • Cycle
    • Cytoplasm
    • Expressed
    • Function
    • Human
    • Known
    • Localization
    • Location
    • Microtubule
    • Mrna
  • centrosome
    • Complex
    • Protein
    • Cycle
    • Centriolar
    • Chromosome
    • Cytoplasm
    • Expressed
    • Function
    • Human
    • Known
    • Localization
    • Location
  • function
    • A4
    • Chromosome
    • Location
    • Bp
    • Chr
    • Material
    • Mouse
    • Pericentriolar
    • Gene
    • Band
    • Binding
    • Centriolar
  • mouse brain
    • Mrna
    • Expression
    • Pericentriolar
    • Band
    • Binding
    • Centriolar
    • Cycle
    • Cytoplasm
    • Expressed
    • Human
    • Localization
    • Microtubule
  • open reading frame
    • A4
    • Chromosome
    • Function
    • Location
    • Bp
    • Chr
    • Material
    • Mouse
    • Pericentriolar
    • Gene
    • Pcm1
    • Protein

Connections between topic areas Semantic bridges

For PCM1, one of the stronger structural bridges in this analysis connects PCM1 with Gene. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PCM1Gene · splits 22 ⟂ 12
PCM1Function · splits 26 ⟂ 8
PCM1Clinical significance · splits 29 ⟂ 5
PCM1Overview · splits 31 ⟂ 3
PCM1Tissue distribution · splits 31 ⟂ 3

Map overview Semantic statistics

PCM1

Nodes34
Edges33
Triples96
Avg. degree1.94
Density0.058824
Components1

Source & methodology

TTTA analyzes the structure around PCM1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Gene, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PCM1 · EN edition · Analysis: TopicsToTalkAbout

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