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Pericentrin (kendrin), also known as PCNT and pericentrin-B (PCNTB), is a protein which in humans is encoded by the PCNT gene on chromosome 21. This protein localizes to the centrosome and recruits proteins to the pericentriolar matrix (PCM) to ensure proper centrosome and mitotic spindle formation, and thus, uninterrupted cell cycle progression. This…
The analysis highlights Structure, Function and Clinical significance as prominent areas in the source structure around PCNT.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PCNT shows recurring relationship patterns in the source. For example, PCNT → calmodulin binding, centriolar satellite, centriole, centrosome, ciliary basal body-plasma membrane docking, cilium assembly, cytoplasm, cytoskeleton, cytosol, G2/M transition of mitotic cell cycle, membrane, microtubule, microtubule cytoskeleton organization, microtubule organizing center, mitotic spindle organization, molecular adaptor activity, positive regulation of intracellular protein transport, protein binding, regulation of G2/M transition of mitotic cell cycle, signal transduction Another extracted example is PCNT → ascending aorta, biceps brachii, body of tongue, extraocular muscle, foot, gastrocnemius muscle, glutes, hand, interventricular septum, middle temporal gyrus, muscle of thigh, primary oocyte, secondary oocyte, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, thoracic diaphragm, triceps brachii muscle, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
protein gene chromosome centrosome bp 21 cell chr human band microtubule pcntb centriole mitotic spindle cycle c-terminus also proteins pcm
TTTA extracted 113 structured relationships around PCNT. Examples in this analysis include PCNT → Aliases → PCNT, KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4, pericentrin and PCNT → Band → 21q22.3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PCNT | Aliases | PCNT, KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4, pericentrin | 1.00 | infobox |
| PCNT | Band | 21q22.3 | 1.00 | infobox |
| PCNT | Band | 10|10 C1 | 1.00 | infobox |
| PCNT | Bgee | gastrocnemius muscle | 1.00 | infobox |
| PCNT | Bgee | body of tongue | 1.00 | infobox |
| PCNT | Bgee | muscle of thigh | 1.00 | infobox |
| PCNT | Bgee | thoracic diaphragm | 1.00 | infobox |
| PCNT | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| PCNT | Bgee | glutes | 1.00 | infobox |
| PCNT | Bgee | triceps brachii muscle | 1.00 | infobox |
| PCNT | Bgee | biceps brachii | 1.00 | infobox |
| PCNT | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| PCNT | Bgee | middle temporal gyrus | 1.00 | infobox |
| PCNT | Bgee | primary oocyte | 1.00 | infobox |
| PCNT | Bgee | zygote | 1.00 | infobox |
| PCNT | Bgee | interventricular septum | 1.00 | infobox |
| PCNT | Bgee | secondary oocyte | 1.00 | infobox |
| PCNT | Bgee | soleus muscle | 1.00 | infobox |
| PCNT | Bgee | hand | 1.00 | infobox |
| PCNT | Bgee | foot | 1.00 | infobox |
| PCNT | Bgee | extraocular muscle | 1.00 | infobox |
| PCNT | Bgee | ascending aorta | 1.00 | infobox |
| PCNT | BioGPS | More reference expression data | 1.00 | infobox |
| PCNT | Chr. | Chromosome 21 (human) | 1.00 | infobox |
| PCNT | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| PCNT | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PCNT | End | 46,445,769 bp | 1.00 | infobox |
| PCNT | End | 76,278,620 bp | 1.00 | infobox |
| PCNT | Ensembl | ENSG00000160299 | 1.00 | infobox |
| PCNT | Entrez | 5116 | 1.00 | infobox |
The concept neighborhoods around PCNT bring nearby vocabulary together. In this analysis, examples include Pcntb, Gene and Cep215. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PCNT, one of the stronger structural bridges in this analysis connects PCNT with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PCNT to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PCNT · EN edition · Analysis: TopicsToTalkAbout