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NKG2D is an activating receptor (transmembrane protein) belonging to the NKG2 family of C-type lectin-like receptors. NKG2D is encoded by KLRK1 (killer cell lectin like receptor K1) gene which is located in the NK-gene complex (NKC) situated on chromosome 6 in mice and chromosome 12 in humans. In mice, it is expressed by NK cells, NK1.1+ T cells, γδ T…
NKG2D ligands, Structure & Function
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cells cell nk receptor ligands dap10 mice expression protein surface human ligand complex 12 bp proteins killer cd8 chromosome mic
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| NKG2D | Aliases | KLRK1, CD314, D12S2489E, KLR, NKG2-D, NKG2D, natural killer group 2D, killer cell lectin-like receptor K1, killer cell lectin like receptor K1 | 1.00 | infobox |
| NKG2D | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KCG, 4PDC, 1HYR, 1MPU, 4S0U | 1.00 | infobox |
| NKG2D | Band | 12p13.2 | 1.00 | infobox |
| NKG2D | Band | 6 F3|6 63.44 cM | 1.00 | infobox |
| NKG2D | Bgee | granulocyte | 1.00 | infobox |
| NKG2D | Bgee | spleen | 1.00 | infobox |
| NKG2D | Bgee | lymph node | 1.00 | infobox |
| NKG2D | Bgee | blood | 1.00 | infobox |
| NKG2D | Bgee | appendix | 1.00 | infobox |
| NKG2D | Bgee | gallbladder | 1.00 | infobox |
| NKG2D | Bgee | upper lobe of left lung | 1.00 | infobox |
| NKG2D | Bgee | mucosa of transverse colon | 1.00 | infobox |
| NKG2D | Bgee | bone marrow | 1.00 | infobox |
| NKG2D | Bgee | testicle | 1.00 | infobox |
| NKG2D | Bgee | superior surface of tongue | 1.00 | infobox |
| NKG2D | Bgee | plantaris muscle | 1.00 | infobox |
| NKG2D | Bgee | extensor digitorum longus muscle | 1.00 | infobox |
| NKG2D | Bgee | morula | 1.00 | infobox |
| NKG2D | Bgee | corneal stroma | 1.00 | infobox |
| NKG2D | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| NKG2D | Bgee | interventricular septum | 1.00 | infobox |
| NKG2D | BioGPS | n/a | 1.00 | infobox |
| NKG2D | Chr. | Chromosome 12 (human) | 1.00 | infobox |
| NKG2D | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| NKG2D | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| NKG2D | End | 10,391,874 bp | 1.00 | infobox |
| NKG2D | End | 129,600,827 bp | 1.00 | infobox |
| NKG2D | Ensembl | ENSG00000213809 | 1.00 | infobox |
| NKG2D | Entrez | 22914 | 1.00 | infobox |
| NKG2D | External IDs | OMIM: 611817; MGI: 1196250; GeneCards: KLRK1 | 1.00 | infobox |
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