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TYRO protein tyrosine kinase-binding protein is an adapter protein that in humans is encoded by the TYROBP gene.
The analysis highlights Function, Interactions and Clinical significance as prominent areas in the source structure around TYROBP.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around TYROBP shows recurring relationship patterns in the source. For example, TYROBP → actin cytoskeleton organization, apoptotic cell clearance, apoptotic signaling pathway, cell surface, cellular defense response, forebrain development, identical protein binding, immune system process, innate immune response, integral component of membrane, integral component of plasma membrane, integrin-mediated signaling pathway, intracellular signal transduction, macrophage activation involved in immune response, membrane, metal ion binding, microglial cell activation involved in immune response, myeloid leukocyte activation, negative regulation of B cell proliferation, negative regulation of long-term synaptic potentiation Another extracted example is TYROBP → blood, bone marrow, bone marrow cell, calvaria, dermis, gallbladder, granulocyte, internal carotid artery, mesenteric lymph nodes, monocyte, periodontal fiber, right lung, right lung lobe, spleen, stroma of bone marrow, tibiofemoral joint, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene bp chr human band protein chromosome 19 plosl tyrosine location signaling mouse receptor signal transduction tyro function external polycystic
TTTA extracted 102 structured relationships around TYROBP. Examples in this analysis include TYROBP → Aliases → TYROBP, DAP12, KARAP, PLOSL, TYRO protein tyrosine kinase binding protein, PLOSL1, transmembrane immune signaling adaptor TYROBP and TYROBP → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L34, 2L35, 4WO1, 4WOL. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TYROBP | Aliases | TYROBP, DAP12, KARAP, PLOSL, TYRO protein tyrosine kinase binding protein, PLOSL1, transmembrane immune signaling adaptor TYROBP | 1.00 | infobox |
| TYROBP | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L34, 2L35, 4WO1, 4WOL | 1.00 | infobox |
| TYROBP | Band | 19q13.12 | 1.00 | infobox |
| TYROBP | Band | 7 B1|7 17.45 cM | 1.00 | infobox |
| TYROBP | Bgee | monocyte | 1.00 | infobox |
| TYROBP | Bgee | granulocyte | 1.00 | infobox |
| TYROBP | Bgee | blood | 1.00 | infobox |
| TYROBP | Bgee | spleen | 1.00 | infobox |
| TYROBP | Bgee | right lung | 1.00 | infobox |
| TYROBP | Bgee | bone marrow | 1.00 | infobox |
| TYROBP | Bgee | periodontal fiber | 1.00 | infobox |
| TYROBP | Bgee | upper lobe of left lung | 1.00 | infobox |
| TYROBP | Bgee | bone marrow cell | 1.00 | infobox |
| TYROBP | Bgee | gallbladder | 1.00 | infobox |
| TYROBP | Bgee | tibiofemoral joint | 1.00 | infobox |
| TYROBP | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| TYROBP | Bgee | calvaria | 1.00 | infobox |
| TYROBP | Bgee | stroma of bone marrow | 1.00 | infobox |
| TYROBP | Bgee | right lung lobe | 1.00 | infobox |
| TYROBP | Bgee | internal carotid artery | 1.00 | infobox |
| TYROBP | Bgee | dermis | 1.00 | infobox |
| TYROBP | BioGPS | More reference expression data | 1.00 | infobox |
| TYROBP | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| TYROBP | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| TYROBP | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TYROBP | End | 35,908,295 bp | 1.00 | infobox |
| TYROBP | End | 30,117,010 bp | 1.00 | infobox |
| TYROBP | Ensembl | ENSG00000011600 | 1.00 | infobox |
| TYROBP | Entrez | 7305 | 1.00 | infobox |
| TYROBP | External IDs | OMIM: 604142; MGI: 1277211; GeneCards: TYROBP | 1.00 | infobox |
The concept neighborhoods around TYROBP bring nearby vocabulary together. In this analysis, examples include Binding, Function and Immune. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TYROBP, one of the stronger structural bridges in this analysis connects TYROBP with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TYROBP to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TYROBP · EN edition · Analysis: TopicsToTalkAbout