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MHC class I polypeptide–related sequence B

MHC class I polypeptide-related sequence B (MICB) is a protein that is encoded by the MICB gene located within MHC locus. MICB is related to MHC class I and has similar domain structure, which is made up of external α1α2α3 domain, transmembrane segment and C-terminal cytoplasmic tail. MICB is a stress-induced ligand for NKG2D receptor. The heat shock…

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Aliases
MICB, PERB11.2, MHC class I polypeptide-related sequence B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JE6, 2WY3
Band
6p21.33 · 7 A3|7 9.35 cM
Bgee
granulocyte · monocyte · blood · stromal cell of endometrium · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 7 (mouse)

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MHC class I polypeptide–related sequence B

Nodes7
Edges6
Triples85
Avg. degree1.71
Density0.285714
Components1

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MHC class I polypeptide–related sequence B

Top relations

Gene ontology · 22
MHC class I polypeptide–related sequence B → adaptive immune response, cell surface, cytolysis, external side of plasma membrane, extracellular space, gamma-delta T cell activation, immune response, immune response-activating cell surface receptor signaling pathway, immune system process, integral component of membrane, membrane, natural killer cell activation, natural killer cell lectin-like receptor binding, natural killer cell mediated cytotoxicity, plasma membrane, regulation of immune response, response to heat, response to oxidative stress, response to retinoic acid, susceptibility to natural killer cell mediated cytotoxicity
Bgee · 20
MHC class I polypeptide–related sequence B → adrenal gland, appendix, blood, bone marrow, bone marrow cell, esophagus, gonad, granulocyte, lung, lymph node, monocyte, muscle tissue, ovary, skeletal muscle tissue, spleen, stromal cell of endometrium, urinary bladder, uterus, white adipose tissue, zone of skin
RNA expression pattern · 20
MHC class I polypeptide–related sequence B → adrenal gland, appendix, blood, bone marrow, bone marrow cell, esophagus, gonad, granulocyte, lung, lymph node, monocyte, muscle tissue, ovary, skeletal muscle tissue, spleen, stromal cell of endometrium, urinary bladder, uterus, white adipose tissue, zone of skin
Band · 2
MHC class I polypeptide–related sequence B → 6p21.33, 7 A3|7 9.35 cM
Chr. · 2
MHC class I polypeptide–related sequence B → Chromosome 6 (human), Chromosome 7 (mouse)
End · 2
MHC class I polypeptide–related sequence B → 18,599,327 bp, 31,511,124 bp
Aliases · 1
MHC class I polypeptide–related sequence B → MICB, PERB11.2, MHC class I polypeptide-related sequence B
Available structures · 1
MHC class I polypeptide–related sequence B → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JE6, 2WY3
BioGPS · 1
MHC class I polypeptide–related sequence B → More reference expression data
Databases · 1
MHC class I polypeptide–related sequence B → NCBI: entry; OMA: entry

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Important terminology

micb bp chr human band gene chromosome mhc class external location protein mouse polypeptide-related sequence receptor heat stress pathway regulation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MHC class I polypeptide–related sequence BAliasesMICB, PERB11.2, MHC class I polypeptide-related sequence B1.00infobox
MHC class I polypeptide–related sequence BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1JE6, 2WY31.00infobox
MHC class I polypeptide–related sequence BBand6p21.331.00infobox
MHC class I polypeptide–related sequence BBand7 A3|7 9.35 cM1.00infobox
MHC class I polypeptide–related sequence BBgeegranulocyte1.00infobox
MHC class I polypeptide–related sequence BBgeemonocyte1.00infobox
MHC class I polypeptide–related sequence BBgeeblood1.00infobox
MHC class I polypeptide–related sequence BBgeestromal cell of endometrium1.00infobox
MHC class I polypeptide–related sequence BBgeelymph node1.00infobox
MHC class I polypeptide–related sequence BBgeebone marrow1.00infobox
MHC class I polypeptide–related sequence BBgeegonad1.00infobox
MHC class I polypeptide–related sequence BBgeebone marrow cell1.00infobox
MHC class I polypeptide–related sequence BBgeespleen1.00infobox
MHC class I polypeptide–related sequence BBgeeappendix1.00infobox
MHC class I polypeptide–related sequence BBgeeurinary bladder1.00infobox
MHC class I polypeptide–related sequence BBgeeuterus1.00infobox
MHC class I polypeptide–related sequence BBgeelung1.00infobox
MHC class I polypeptide–related sequence BBgeeovary1.00infobox
MHC class I polypeptide–related sequence BBgeewhite adipose tissue1.00infobox
MHC class I polypeptide–related sequence BBgeeadrenal gland1.00infobox
MHC class I polypeptide–related sequence BBgeezone of skin1.00infobox
MHC class I polypeptide–related sequence BBgeeesophagus1.00infobox
MHC class I polypeptide–related sequence BBgeemuscle tissue1.00infobox
MHC class I polypeptide–related sequence BBgeeskeletal muscle tissue1.00infobox
MHC class I polypeptide–related sequence BBioGPSMore reference expression data1.00infobox
MHC class I polypeptide–related sequence BChr.Chromosome 6 (human)1.00infobox
MHC class I polypeptide–related sequence BChr.Chromosome 7 (mouse)1.00infobox
MHC class I polypeptide–related sequence BDatabasesNCBI: entry; OMA: entry1.00infobox
MHC class I polypeptide–related sequence BEnd31,511,124 bp1.00infobox
MHC class I polypeptide–related sequence BEnd18,599,327 bp1.00infobox

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