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NEDD8 is a protein that in humans is encoded by the NEDD8 gene. (in Saccharomyces cerevisiae this protein is known as Rub1) This ubiquitin-like (UBL) protein becomes covalently conjugated to a limited number of cellular proteins, in a process called NEDDylation similar to ubiquitination. Human NEDD8 shares 60% amino acid sequence identity to ubiquitin.…
Research, In cancer chemotherapy & Substrates for NEDD8
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ubiquitin neddylation dna repair human pevonedistat bp gene protein cancer chr band cell activation nhej chromosome 14 ubiquitination substrates process
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| NEDD8 | Aliases | NEDD8, NEDD-8, neural precursor cell expressed, developmentally down-regulated 8, NEDD8 ubiquitin like modifier | 1.00 | infobox |
| NEDD8 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1NDD, 1R4M, 1R4N, 1XT9, 2BKR, 2KO3, 2NVU, 3DBH, 3DBL, 3DBR, 3DQV, 3GZN, 4F8C, 4FBJ, 4HCP, 4P5O | 1.00 | infobox |
| NEDD8 | Band | 14q12 | 1.00 | infobox |
| NEDD8 | Band | 14 C3|14 28.19 cM | 1.00 | infobox |
| NEDD8 | Bgee | prefrontal cortex | 1.00 | infobox |
| NEDD8 | Bgee | superior frontal gyrus | 1.00 | infobox |
| NEDD8 | Bgee | right frontal lobe | 1.00 | infobox |
| NEDD8 | Bgee | anterior cingulate cortex | 1.00 | infobox |
| NEDD8 | Bgee | dorsolateral prefrontal cortex | 1.00 | infobox |
| NEDD8 | Bgee | nucleus accumbens | 1.00 | infobox |
| NEDD8 | Bgee | primary visual cortex | 1.00 | infobox |
| NEDD8 | Bgee | apex of heart | 1.00 | infobox |
| NEDD8 | Bgee | hypothalamus | 1.00 | infobox |
| NEDD8 | Bgee | caudate nucleus | 1.00 | infobox |
| NEDD8 | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| NEDD8 | Bgee | ventricular zone | 1.00 | infobox |
| NEDD8 | Bgee | somite | 1.00 | infobox |
| NEDD8 | Bgee | neural layer of retina | 1.00 | infobox |
| NEDD8 | Bgee | blastocyst | 1.00 | infobox |
| NEDD8 | Bgee | morula | 1.00 | infobox |
| NEDD8 | Bgee | embryo | 1.00 | infobox |
| NEDD8 | Bgee | maxillary prominence | 1.00 | infobox |
| NEDD8 | Bgee | epiblast | 1.00 | infobox |
| NEDD8 | BioGPS | More reference expression data | 1.00 | infobox |
| NEDD8 | Chr. | Chromosome 14 (human) | 1.00 | infobox |
| NEDD8 | Chr. | Chromosome 14 (mouse) | 1.00 | infobox |
| NEDD8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| NEDD8 | End | 24,232,367 bp | 1.00 | infobox |
| NEDD8 | End | 55,909,581 bp | 1.00 | infobox |
| NEDD8 | Ensembl | ENSG00000129559 ENSG00000285246 | 1.00 | infobox |
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