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Na–K–Cl cotransporter

The Na–K–Cl cotransporter (NKCC) is a transport protein that aids in the secondary active transport of sodium, potassium, and chloride into cells. In humans there are two isoforms of this membrane transport protein, NKCC1 and NKCC2, encoded by two different genes (SLC12A2 and SLC12A1 respectively). Two isoforms of the NKCC1/Slc12a2 gene result from…

Standards, Function & Genetics

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Alt. symbols
NKCC2
Domains
InterPro
HGNC
10910
Locus
Chr. 15 q21.1
NCBI gene
6557
OMIM
600839

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Genetics

Kinetics

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Map overview Semantic statistics

Na–K–Cl cotransporter

Nodes109
Edges108
Triples12
Avg. degree1.98
Density0.018349
Components1

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Na–K–Cl cotransporter

Top relations

Alt. symbols · 1
Na–K–Cl cotransporter → NKCC2
Domains · 1
Na–K–Cl cotransporter → InterPro
HGNC · 1
Na–K–Cl cotransporter → 10910
Locus · 1
Na–K–Cl cotransporter → Chr. 15 q21.1
NCBI gene · 1
Na–K–Cl cotransporter → 6557
OMIM · 1
Na–K–Cl cotransporter → 600839
Orthologs · 1
Na–K–Cl cotransporter → 286
RefSeq · 1
Na–K–Cl cotransporter → NM_000338
Search for · 1
Na–K–Cl cotransporter → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Na–K–Cl cotransporter → Swiss-model

Important terminology Word statistics

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Important terminology

nkcc1 sodium nkcc2 chloride potassium blood thick ascending limb membrane cells transport cotransporter urine isoform loop protein two isoforms slc12a2

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Na–K–Cl cotransporterAlt. symbolsNKCC21.00infobox
Na–K–Cl cotransporterDomainsInterPro1.00infobox
Na–K–Cl cotransporterHGNC109101.00infobox
Na–K–Cl cotransporterLocusChr. 15 q21.11.00infobox
Na–K–Cl cotransporterNCBI gene65571.00infobox
Na–K–Cl cotransporterOMIM6008391.00infobox
Na–K–Cl cotransporterOrthologs2861.00infobox
Na–K–Cl cotransporterRefSeqNM_0003381.00infobox
Na–K–Cl cotransporterSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Na–K–Cl cotransporterStructuresSwiss-model1.00infobox
Na–K–Cl cotransporterSymbolSLC12A11.00infobox
Na–K–Cl cotransporterUniProtQ136211.00infobox

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