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SIX4: Overview, Related Topics & Entities

Homeobox protein SIX4 is a protein that in humans is encoded by the SIX4 gene.

Language: English [EN]
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SIX4 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around SIX4.

Related topics
2
Source areas
1
Connected nodes
3
Extracted relationships
108
Concept neighborhoods
4
Bridge connections
3

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SIX4, AREC3, SIX homeobox 4
Band
14q23.1 · 12|12 C3
Bgee
bronchial epithelial cell · vastus lateralis muscle · Skeletal muscle tissue of biceps brachii · Skeletal muscle tissue of rectus abdominis · deltoid muscle
BioGPS
n/a
Chr.
Chromosome 14 (human) · Chromosome 12 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SIX4 connects Entity context

The extracted context around SIX4 shows recurring relationship patterns in the source. For example, SIX4 → anatomical structure development, anatomical structure morphogenesis, cytoplasm, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic cranial skeleton morphogenesis, embryonic skeletal system morphogenesis, fungiform papilla morphogenesis, generation of neurons, inner ear morphogenesis, male gonad development, male sex determination, male sex differentiation, metanephric mesenchyme development, multicellular organism development, myoblast migration, myotome development, negative regulation of apoptotic process Another extracted example is SIX4 → bronchial epithelial cell, cartilage tissue, deltoid muscle, digastric muscle, epithelium of nasopharynx, foot, intercostal muscle, lobe of prostate, lumbar spinal ganglion, mandibular prominence, maxillary prominence, mucosa of paranasal sinus, nasal epithelium, parotid gland, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, utricle, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

SIX4

Top relations

Gene ontology · 49
SIX4 → anatomical structure development, anatomical structure morphogenesis, cytoplasm, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic cranial skeleton morphogenesis, embryonic skeletal system morphogenesis, fungiform papilla morphogenesis, generation of neurons, inner ear morphogenesis, male gonad development, male sex determination, male sex differentiation, metanephric mesenchyme development, multicellular organism development, myoblast migration, myotome development, negative regulation of apoptotic process
Bgee · 19
SIX4 → bronchial epithelial cell, cartilage tissue, deltoid muscle, digastric muscle, epithelium of nasopharynx, foot, intercostal muscle, lobe of prostate, lumbar spinal ganglion, mandibular prominence, maxillary prominence, mucosa of paranasal sinus, nasal epithelium, parotid gland, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, utricle, vastus lateralis muscle
RNA expression pattern · 19
SIX4 → bronchial epithelial cell, cartilage tissue, deltoid muscle, digastric muscle, epithelium of nasopharynx, foot, intercostal muscle, lobe of prostate, lumbar spinal ganglion, mandibular prominence, maxillary prominence, mucosa of paranasal sinus, nasal epithelium, parotid gland, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, utricle, vastus lateralis muscle
Band · 2
SIX4 → 12|12 C3, 14q23.1
Chr. · 2
SIX4 → Chromosome 12 (mouse), Chromosome 14 (human)
End · 2
SIX4 → 60,724,351 bp, 73,160,230 bp
Aliases · 1
SIX4 → SIX4, AREC3, SIX homeobox 4
BioGPS · 1
SIX4 → n/a
Databases · 1
SIX4 → NCBI: entry; OMA: entry
Ensembl · 1
SIX4 → ENSG00000100625

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp chr human band gene chromosome 14 location protein mouse homeobox 724 351 end 60 12 160 230 humans encoded

SIX4 relationships Subject–Predicate–Object triples

TTTA extracted 108 structured relationships around SIX4. Examples in this analysis include SIX4 → Aliases → SIX4, AREC3, SIX homeobox 4 and SIX4 → Band → 14q23.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SIX4AliasesSIX4, AREC3, SIX homeobox 41.00infobox
SIX4Band14q23.11.00infobox
SIX4Band12|12 C31.00infobox
SIX4Bgeebronchial epithelial cell1.00infobox
SIX4Bgeevastus lateralis muscle1.00infobox
SIX4BgeeSkeletal muscle tissue of biceps brachii1.00infobox
SIX4BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
SIX4Bgeedeltoid muscle1.00infobox
SIX4Bgeenasal epithelium1.00infobox
SIX4Bgeemucosa of paranasal sinus1.00infobox
SIX4Bgeecartilage tissue1.00infobox
SIX4Bgeeparotid gland1.00infobox
SIX4Bgeeepithelium of nasopharynx1.00infobox
SIX4Bgeelumbar spinal ganglion1.00infobox
SIX4Bgeeintercostal muscle1.00infobox
SIX4Bgeemaxillary prominence1.00infobox
SIX4Bgeeutricle1.00infobox
SIX4Bgeefoot1.00infobox
SIX4Bgeesoleus muscle1.00infobox
SIX4Bgeedigastric muscle1.00infobox
SIX4Bgeemandibular prominence1.00infobox
SIX4Bgeelobe of prostate1.00infobox
SIX4BioGPSn/a1.00infobox
SIX4Chr.Chromosome 14 (human)1.00infobox
SIX4Chr.Chromosome 12 (mouse)1.00infobox
SIX4DatabasesNCBI: entry; OMA: entry1.00infobox
SIX4End60,724,351 bp1.00infobox
SIX4End73,160,230 bp1.00infobox
SIX4EnsemblENSG000001006251.00infobox
SIX4Entrez518041.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SIX4 bring nearby vocabulary together. In this analysis, examples include Gene, Homeobox and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SIX4
    • Gene
    • Homeobox
    • Protein
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Encoded
    • Humans
    • Reading
    • References
  • six4
    • Gene
    • Homeobox
    • Protein
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Encoded
    • Humans
    • Reading
    • References
  • gene
    • Location
    • Six4
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Homeobox
    • Mouse
    • Protein
    • Band
    • Humans
  • protein
    • Six4
    • Humans
    • End
    • Mouse
    • Location
    • Band
    • Chromosome
    • Human
    • Bp
    • Chr

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the SIX4 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

SIX4

Nodes4
Edges3
Triples108
Avg. degree1.5
Density0.5
Components1

Source & methodology

TTTA analyzes the structure around SIX4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SIX4 · EN edition · Analysis: TopicsToTalkAbout

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