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MT-ND3: Measurement, Structure & Clinical significance

MT-ND3 is a gene of the mitochondrial genome coding for the NADH dehydrogenase 3 (ND3) protein. The ND3 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variants of MT-ND3 are associated with Mitochondrial…

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MT-ND3 topic overview

The analysis highlights Measurement, Structure and Clinical significance as prominent areas in the source structure around MT-ND3.

Related topics
45
Source areas
5
Connected nodes
50
Extracted relationships
134
Concept neighborhoods
19
Bridge connections
50

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 15 topics
Clinical significance · 13 topics
Overview · 8 topics
Function · 7 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

7.1.1.2
Aliases
ND3, MTMT-NADH dehydrogenase, subunit 3 (complex I), NADH dehydrogenase subunit 3
Band
n/a
Bgee
right uterine tube · right auricle of heart · granulocyte · Brodmann area 9 · muscle layer of sigmoid colon
BioGPS
n/a
Chr.
Mitochondrial DNA (human) · Mitochondrial DNA (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MT-ND3 connects Entity context

The extracted context around MT-ND3 shows recurring relationship patterns in the source. For example, MT-ND3 → Brodmann area 9, duodenum, granulocyte, hippocampus proper, hypothalamus, islet of Langerhans, lactiferous gland, left adrenal cortex, lip, muscle layer of sigmoid colon, muscle of thigh, neural layer of retina, olfactory bulb, prostate, quadriceps femoris muscle, right adrenal gland, right auricle of heart, right uterine tube, subcutaneous adipose tissue, superior frontal gyrus Another extracted example is MT-ND3 → Abnormalities, Leber's, Leigh, LHON, MELAS, MT-ATP6, MT-CO3, MT-ND1, MT-ND2, MT-ND4, MT-ND5, MT-ND6, MT-TK, MT-TL1, MT-TV, MT-TW, Pathogenic, Roughly, The, These. Use these groups to spot repeated connection types before inspecting the individual relationships.

MT-ND3

Top relations

Bgee · 20
MT-ND3 → Brodmann area 9, duodenum, granulocyte, hippocampus proper, hypothalamus, islet of Langerhans, lactiferous gland, left adrenal cortex, lip, muscle layer of sigmoid colon, muscle of thigh, neural layer of retina, olfactory bulb, prostate, quadriceps femoris muscle, right adrenal gland, right auricle of heart, right uterine tube, subcutaneous adipose tissue, superior frontal gyrus
RNA expression pattern · 20
MT-ND3 → Brodmann area 9, duodenum, granulocyte, hippocampus proper, hypothalamus, islet of Langerhans, lactiferous gland, left adrenal cortex, lip, muscle layer of sigmoid colon, muscle of thigh, neural layer of retina, olfactory bulb, prostate, quadriceps femoris muscle, right adrenal gland, right auricle of heart, right uterine tube, subcutaneous adipose tissue, superior frontal gyrus
related to Clinical significance · 20
MT-ND3 → Abnormalities, Leber's, Leigh, LHON, MELAS, MT-ATP6, MT-CO3, MT-ND1, MT-ND2, MT-ND4, MT-ND5, MT-ND6, MT-TK, MT-TL1, MT-TV, MT-TW, Pathogenic, Roughly, The, These
Gene ontology · 17
MT-ND3 → cellular response to glucocorticoid stimulus, integral component of membrane, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial membranes, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase complex, oxidoreductase activity, protein binding, respirasome, response to hormone, response to light intensity, response to oxidative stress
related to General features · 13
MT-ND3 → Also, Complex, DNA, L-shaped, MT-ND1, MT-ND2, MT-ND4, MT-ND4L, MT-ND5, MT-ND6, NADH, The, The MT-ND3
related to Function · 11
MT-ND3 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, Initially, NADH, Q10, The, The MT-ND3
related to Untranslated extra nucleotide · 7
MT-ND3 → Archosauria, In, ND3, RNA, The, This, Translational
Chr. · 2
MT-ND3 → Mitochondrial DNA (human), Mitochondrial DNA (mouse)
End · 2
MT-ND3 → 10,404 bp, 9,806 bp
related to External links · 2
MT-ND3 → COPaKB, Mass

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mitochondrial nadh gene bp protein human complex dehydrogenase chr band dna nd3 ubiquinone syndrome chain extra nucleotide respiratory subunit electron

MT-ND3 relationships Subject–Predicate–Object triples

TTTA extracted 134 structured relationships around MT-ND3. Examples in this analysis include MT-ND3 → 7.1.1.2 → ↗ and MT-ND3 → Aliases → ND3, MTMT-NADH dehydrogenase, subunit 3 (complex I), NADH dehydrogenase subunit 3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MT-ND37.1.1.21.00infobox
MT-ND3AliasesND3, MTMT-NADH dehydrogenase, subunit 3 (complex I), NADH dehydrogenase subunit 31.00infobox
MT-ND3Bandn/a1.00infobox
MT-ND3Bgeeright uterine tube1.00infobox
MT-ND3Bgeeright auricle of heart1.00infobox
MT-ND3Bgeegranulocyte1.00infobox
MT-ND3BgeeBrodmann area 91.00infobox
MT-ND3Bgeemuscle layer of sigmoid colon1.00infobox
MT-ND3Bgeelactiferous gland1.00infobox
MT-ND3Bgeesubcutaneous adipose tissue1.00infobox
MT-ND3Bgeeright adrenal gland1.00infobox
MT-ND3Bgeeleft adrenal cortex1.00infobox
MT-ND3Bgeeprostate1.00infobox
MT-ND3Bgeehypothalamus1.00infobox
MT-ND3Bgeehippocampus proper1.00infobox
MT-ND3Bgeeolfactory bulb1.00infobox
MT-ND3Bgeelip1.00infobox
MT-ND3Bgeequadriceps femoris muscle1.00infobox
MT-ND3Bgeeislet of Langerhans1.00infobox
MT-ND3Bgeesuperior frontal gyrus1.00infobox
MT-ND3Bgeeduodenum1.00infobox
MT-ND3Bgeeneural layer of retina1.00infobox
MT-ND3Bgeemuscle of thigh1.00infobox
MT-ND3BioGPSn/a1.00infobox
MT-ND3Chr.Mitochondrial DNA (human)1.00infobox
MT-ND3Chr.Mitochondrial DNA (mouse)1.00infobox
MT-ND3DatabasesNCBI: entry; OMA: entry1.00infobox
MT-ND3End10,404 bp1.00infobox
MT-ND3End9,806 bp1.00infobox
MT-ND3EnsemblENSG000001988401.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MT-ND3 bring nearby vocabulary together. In this analysis, examples include Protein, Nadh and Ubiquinone. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MT-ND3
    • Protein
    • Nadh
    • Ubiquinone
    • Dehydrogenase
    • Syndrome
    • Complex
    • Electron
    • Genes
    • Chain
    • Leigh
    • Respiratory
    • Function
  • mt-nd3
    • Protein
    • Nadh
    • Ubiquinone
    • Dehydrogenase
    • Syndrome
    • Complex
    • Electron
    • Genes
    • Chain
    • Leigh
    • Respiratory
    • Function
  • gene
    • Protein
    • Location
    • Dna
    • Human
    • Bp
    • Chr
    • Dehydrogenase
    • Mitochondrial
    • Mt-nd3
    • Function
    • Mouse
    • Nadh
  • mitochondrial genome
    • Dehydrogenase
    • Syndrome
    • Nadh
    • Dna
    • Human
    • Leigh
    • Mt-nd3
    • Bp
    • Chr
    • Protein
    • Genes
    • Location
  • nadh dehydrogenase (ubiquinone)
    • Electron
    • Nadh
    • Chain
    • Dehydrogenase
    • Inner
    • Membrane
    • Nd3
    • Transport
    • Ubiquinone
    • Function
    • Subunit
    • Mitochondrial
  • mitochondrial inner membrane
    • Membrane
    • Transport
    • Electron
    • Chain
    • Ubiquinone
    • Dehydrogenase
    • Syndrome
    • Function
    • Mouse
    • Protein
    • Nadh
    • Dna
  • electron transport chain
    • Chain
    • Electron
    • Ubiquinone
    • Inner
    • Membrane
    • Transport
    • Subunit
    • Protein
    • Respiratory
    • Nadh
    • Function
    • Mouse
  • mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes
    • Dehydrogenase
    • Syndrome
    • Nadh
    • Dna
    • Human
    • Leigh
    • Mt-nd3
    • Bp
    • Chr
    • Protein
    • Genes
    • Location

Connections between topic areas Semantic bridges

For MT-ND3, one of the stronger structural bridges in this analysis connects MT-ND3 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MT-ND3Structure · splits 35 ⟂ 16
MT-ND3Clinical significance · splits 37 ⟂ 14
MT-ND3Overview · splits 42 ⟂ 9
MT-ND3Function · splits 43 ⟂ 8
MT-ND3Interactions · splits 48 ⟂ 3

Map overview Semantic statistics

MT-ND3

Nodes51
Edges50
Triples134
Avg. degree1.96
Density0.039216
Components1

Source & methodology

TTTA analyzes the structure around MT-ND3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Structure & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MT-ND3 · EN edition · Analysis: TopicsToTalkAbout

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