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MT-ND2

MT-ND2 is a gene of the mitochondrial genome coding for the NADH dehydrogenase 2 (ND2) protein. The ND2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variants of human MT-ND2 are associated with mitochondrial…

Measurement, Structure & Clinical significance

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MT-ND2 at a glance

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7.1.1.2
Aliases
ND2, complex I ND2 subunit, NAD2, NADH-ubiquinone oxidoreductase chain 2, MT-MTNADH dehydrogenase subunit 2
Band
n/a
Bgee
subcutaneous adipose tissue · caudate nucleus · putamen · lactiferous gland · right uterine tube
BioGPS
n/a
Chr.
Mitochondrial DNA (human) · Mitochondrial DNA (mouse)

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Overview

Structure

Function

Clinical significance

Advanced semantic analysis

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MT-ND2

Top relations

related to Clinical significance · 23
MT-ND2 → Abnormalities, BMI, Leber's, Leigh, LHON, MELAS, Mitochondrial, MT-ATP6, MT-CO3, MT-ND1, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6, MT-TK, MT-TL1, MT-TV, MT-TW, Pathogenic
Bgee · 20
MT-ND2 → adrenal gland, C1 segment, caudate nucleus, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, esophagus, hippocampus proper, hypothalamus, lactiferous gland, left uterine tube, muscle layer of sigmoid colon, neural layer of retina, primary visual cortex, putamen, right hemisphere of cerebellum, right uterine tube, striatum of neuraxis, subcutaneous adipose tissue, substantia nigra, superior frontal gyrus
RNA expression pattern · 20
MT-ND2 → adrenal gland, C1 segment, caudate nucleus, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, esophagus, hippocampus proper, hypothalamus, lactiferous gland, left uterine tube, muscle layer of sigmoid colon, neural layer of retina, primary visual cortex, putamen, right hemisphere of cerebellum, right uterine tube, striatum of neuraxis, subcutaneous adipose tissue, substantia nigra, superior frontal gyrus
Gene ontology · 14
MT-ND2 → integral component of membrane, ionotropic glutamate receptor binding, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, oxidoreductase activity, postsynaptic density, protein kinase binding, reactive oxygen species metabolic process, respirasome
related to Structure · 13
MT-ND2 → Also, Complex, DNA, L-shaped, MT-ND1, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6, NADH, The, The MT-ND2
related to Function · 11
MT-ND2 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, Initially, NADH, Q10, The, The MT-ND2
related to External links · 3
MT-ND2 → COPaKB Archived, Mass, Wayback Machine
Chr. · 2
MT-ND2 → Mitochondrial DNA (human), Mitochondrial DNA (mouse)
End · 2
MT-ND2 → 4,951 bp, 5,511 bp
7.1.1.2 · 1
MT-ND2 → ↗

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Important terminology

mitochondrial nadh human bp gene protein complex dehydrogenase chr band chain dna ubiquinone syndrome nd2 respiratory subunit electron location leigh

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
MT-ND27.1.1.21.00infobox
MT-ND2AliasesND2, complex I ND2 subunit, NAD2, NADH-ubiquinone oxidoreductase chain 2, MT-MTNADH dehydrogenase subunit 21.00infobox
MT-ND2Bandn/a1.00infobox
MT-ND2Bgeesubcutaneous adipose tissue1.00infobox
MT-ND2Bgeecaudate nucleus1.00infobox
MT-ND2Bgeeputamen1.00infobox
MT-ND2Bgeelactiferous gland1.00infobox
MT-ND2Bgeeright uterine tube1.00infobox
MT-ND2BgeeC1 segment1.00infobox
MT-ND2Bgeemuscle layer of sigmoid colon1.00infobox
MT-ND2Bgeeleft uterine tube1.00infobox
MT-ND2Bgeeright hemisphere of cerebellum1.00infobox
MT-ND2Bgeesubstantia nigra1.00infobox
MT-ND2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
MT-ND2Bgeehypothalamus1.00infobox
MT-ND2Bgeestriatum of neuraxis1.00infobox
MT-ND2Bgeeprimary visual cortex1.00infobox
MT-ND2Bgeesuperior frontal gyrus1.00infobox
MT-ND2Bgeecerebellar cortex1.00infobox
MT-ND2Bgeeadrenal gland1.00infobox
MT-ND2Bgeehippocampus proper1.00infobox
MT-ND2Bgeeneural layer of retina1.00infobox
MT-ND2Bgeeesophagus1.00infobox
MT-ND2BioGPSn/a1.00infobox
MT-ND2Chr.Mitochondrial DNA (human)1.00infobox
MT-ND2Chr.Mitochondrial DNA (mouse)1.00infobox
MT-ND2DatabasesNCBI: entry; OMA: entry1.00infobox
MT-ND2End5,511 bp1.00infobox
MT-ND2End4,951 bp1.00infobox
MT-ND2EnsemblENSG000001987631.00infobox

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    MT-ND2

    Nodes39
    Edges38
    Triples126
    Avg. degree1.95
    Density0.051282
    Components1
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