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MT-ND1

MT-ND1 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 1 (ND1) protein. The ND1 protein is a subunit of NADH dehydrogenase, which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variants of the human MT-ND1 gene are associated with…

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7.1.1.2
Aliases
ND1, MTMT-NADH dehydrogenase, subunit 1 (complex I), NADH dehydrogenase subunit 1
Band
n/a
Bgee
subcutaneous adipose tissue · right hemisphere of cerebellum · right testis · right frontal lobe · left testis
BioGPS
n/a
Chr.
Mitochondrial DNA (human) · Mitochondrial DNA (mouse)

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MT-ND1

Nodes41
Edges40
Triples128
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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MT-ND1

Top relations

related to Clinical significance · 25
MT-ND1 → A/MT-ND1, Abnormalities, BMI, Leber's, Leigh, Leigh-like, LHON, MELAS, Mitochondrial, MT-ATP6, MT-CO3, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6, MT-TK, MT-TL1, MT-TV
Gene ontology · 19
MT-ND1 → aerobic dissimilation, cellular respiration, dendrite, integral component of membrane, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial membranes, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, NADH dehydrogenase activity, oxidoreductase activity, protein binding, respirasome, response to hydroperoxide, response to organic cyclic compound, soma
Bgee · 18
MT-ND1 → cerebellum, gastrocnemius muscle, genital tubercle, hypothalamus, left testis, olfactory bulb, olfactory zone of nasal mucosa, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, right kidney, right testis, striatum of neuraxis, subcutaneous adipose tissue, superior frontal gyrus, tail of embryo, yolk sac
RNA expression pattern · 18
MT-ND1 → cerebellum, gastrocnemius muscle, genital tubercle, hypothalamus, left testis, olfactory bulb, olfactory zone of nasal mucosa, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, right kidney, right testis, striatum of neuraxis, subcutaneous adipose tissue, superior frontal gyrus, tail of embryo, yolk sac
related to Structure · 13
MT-ND1 → Also, Complex, DNA, L-shaped, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6, NADH, The, The MT-ND1
related to Function · 11
MT-ND1 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, Initially, MT-ND1-encoded NADH-ubiquinone, NADH, Q10, The
Chr. · 2
MT-ND1 → Mitochondrial DNA (human), Mitochondrial DNA (mouse)
End · 2
MT-ND1 → 3,707 bp, 4,262 bp
related to External links · 2
MT-ND1 → COPaKB, Mass
7.1.1.2 · 1
MT-ND1 → ↗

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Important terminology

mitochondrial gene nadh human bp protein complex chain chr band dna syndrome dehydrogenase nd1 respiratory oxidoreductase subunit electron location ubiquinone

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MT-ND17.1.1.21.00infobox
MT-ND1AliasesND1, MTMT-NADH dehydrogenase, subunit 1 (complex I), NADH dehydrogenase subunit 11.00infobox
MT-ND1Bandn/a1.00infobox
MT-ND1Bgeesubcutaneous adipose tissue1.00infobox
MT-ND1Bgeeright hemisphere of cerebellum1.00infobox
MT-ND1Bgeeright testis1.00infobox
MT-ND1Bgeeright frontal lobe1.00infobox
MT-ND1Bgeeleft testis1.00infobox
MT-ND1Bgeegastrocnemius muscle1.00infobox
MT-ND1Bgeesuperior frontal gyrus1.00infobox
MT-ND1Bgeeprimary visual cortex1.00infobox
MT-ND1Bgeeolfactory zone of nasal mucosa1.00infobox
MT-ND1Bgeeprefrontal cortex1.00infobox
MT-ND1Bgeetail of embryo1.00infobox
MT-ND1Bgeestriatum of neuraxis1.00infobox
MT-ND1Bgeeolfactory bulb1.00infobox
MT-ND1Bgeeyolk sac1.00infobox
MT-ND1Bgeecerebellum1.00infobox
MT-ND1Bgeehypothalamus1.00infobox
MT-ND1Bgeegenital tubercle1.00infobox
MT-ND1Bgeeright kidney1.00infobox
MT-ND1BioGPSn/a1.00infobox
MT-ND1Chr.Mitochondrial DNA (human)1.00infobox
MT-ND1Chr.Mitochondrial DNA (mouse)1.00infobox
MT-ND1DatabasesNCBI: entry; OMA: entry1.00infobox
MT-ND1End4,262 bp1.00infobox
MT-ND1End3,707 bp1.00infobox
MT-ND1EnsemblENSG000001988881.00infobox
MT-ND1Entrez45351.00infobox
MT-ND1Enzyme activityEnzyme activityEC #BRENDAExPASyKEGGMetaCyc7.1.1.2↗↗↗↗1.00infobox

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