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Cytochrome c oxidase subunit III

Cytochrome c oxidase subunit III (COX3) is an enzyme that in humans is encoded by the MT-CO3 gene. It is one of main transmembrane subunits of cytochrome c oxidase. It is also one of the three mitochondrial DNA (mtDNA) encoded subunits (MT-CO1, MT-CO2, MT-CO3) of respiratory complex IV. Variants of it have been associated with isolated myopathy, severe…

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7.1.1.9
↗
Aliases
COX3, COIII, MTCO3, Cytochrome c oxidase subunit III, cytochrome c oxidase III
Band
n/a
Bgee
gastric mucosa · skin of abdomen · skin of leg · left testis · right testis
BioGPS
n/a
Chr.
Mitochondrial DNA (human) · Mitochondrial DNA (mouse)

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Cytochrome c oxidase subunit III

Nodes52
Edges51
Triples78
Avg. degree1.96
Density0.038462
Components1

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Cytochrome c oxidase subunit III

Top relations

Bgee · 20
Cytochrome c oxidase subunit III → amygdala, apex of heart, bone marrow, duodenum, epiblast, ganglionic eminence, gastric mucosa, hippocampus proper, jejunum, left testis, mucosa of transverse colon, olfactory zone of nasal mucosa, proximal tubule, quadriceps femoris muscle, right kidney, right testis, skin of abdomen, skin of leg, ventricular zone, zone of skin
RNA expression pattern · 20
Cytochrome c oxidase subunit III → amygdala, apex of heart, bone marrow, duodenum, epiblast, ganglionic eminence, gastric mucosa, hippocampus proper, jejunum, left testis, mucosa of transverse colon, olfactory zone of nasal mucosa, proximal tubule, quadriceps femoris muscle, right kidney, right testis, skin of abdomen, skin of leg, ventricular zone, zone of skin
Gene ontology · 17
Cytochrome c oxidase subunit III → aerobic dissimilation, aerobic electron transport chain, cytochrome-c oxidase activity, electron transfer activity, integral component of membrane, membrane, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial inner membrane, mitochondrial respiratory chain complex IV, mitochondrion, oxidoreduction-driven active transmembrane transporter activity, protein binding, proton transmembrane transport, respiratory chain complex IV, respiratory chain complex IV assembly, respiratory electron transport chain, transmembrane transport
Chr. · 2
Cytochrome c oxidase subunit III → Mitochondrial DNA (human), Mitochondrial DNA (mouse)
End · 2
Cytochrome c oxidase subunit III → 9,390 bp, 9,990 bp
7.1.1.9 · 1
Cytochrome c oxidase subunit III → ↗
Aliases · 1
Cytochrome c oxidase subunit III → COX3, COIII, MTCO3, Cytochrome c oxidase subunit III, cytochrome c oxidase III
Band · 1
Cytochrome c oxidase subunit III → n/a
BioGPS · 1
Cytochrome c oxidase subunit III → n/a
Databases · 1
Cytochrome c oxidase subunit III → NCBI: entry; OMA: entry

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Important terminology

mitochondrial cytochrome oxidase complex iv dna bp gene subunit human cox3 respiratory chr band associated subunits deficiency iii myoglobinuria optic

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SubjectPredicateObjectConfidenceSrc
Cytochrome c oxidase subunit III7.1.1.9↗1.00infobox
Cytochrome c oxidase subunit IIIAliasesCOX3, COIII, MTCO3, Cytochrome c oxidase subunit III, cytochrome c oxidase III1.00infobox
Cytochrome c oxidase subunit IIIBandn/a1.00infobox
Cytochrome c oxidase subunit IIIBgeegastric mucosa1.00infobox
Cytochrome c oxidase subunit IIIBgeeskin of abdomen1.00infobox
Cytochrome c oxidase subunit IIIBgeeskin of leg1.00infobox
Cytochrome c oxidase subunit IIIBgeeleft testis1.00infobox
Cytochrome c oxidase subunit IIIBgeeright testis1.00infobox
Cytochrome c oxidase subunit IIIBgeemucosa of transverse colon1.00infobox
Cytochrome c oxidase subunit IIIBgeeapex of heart1.00infobox
Cytochrome c oxidase subunit IIIBgeeolfactory zone of nasal mucosa1.00infobox
Cytochrome c oxidase subunit IIIBgeeamygdala1.00infobox
Cytochrome c oxidase subunit IIIBgeehippocampus proper1.00infobox
Cytochrome c oxidase subunit IIIBgeequadriceps femoris muscle1.00infobox
Cytochrome c oxidase subunit IIIBgeeright kidney1.00infobox
Cytochrome c oxidase subunit IIIBgeeproximal tubule1.00infobox
Cytochrome c oxidase subunit IIIBgeeduodenum1.00infobox
Cytochrome c oxidase subunit IIIBgeeepiblast1.00infobox
Cytochrome c oxidase subunit IIIBgeeventricular zone1.00infobox
Cytochrome c oxidase subunit IIIBgeeganglionic eminence1.00infobox
Cytochrome c oxidase subunit IIIBgeezone of skin1.00infobox
Cytochrome c oxidase subunit IIIBgeejejunum1.00infobox
Cytochrome c oxidase subunit IIIBgeebone marrow1.00infobox
Cytochrome c oxidase subunit IIIBioGPSn/a1.00infobox
Cytochrome c oxidase subunit IIIChr.Mitochondrial DNA (human)1.00infobox
Cytochrome c oxidase subunit IIIChr.Mitochondrial DNA (mouse)1.00infobox
Cytochrome c oxidase subunit IIIDatabasesNCBI: entry; OMA: entry1.00infobox
Cytochrome c oxidase subunit IIIEnd9,990 bp1.00infobox
Cytochrome c oxidase subunit IIIEnd9,390 bp1.00infobox
Cytochrome c oxidase subunit IIIEnsemblENSG000001989381.00infobox

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