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MT-ND6

MT-ND6 is a gene of the mitochondrial genome coding for the NADH-ubiquinone oxidoreductase chain 6 protein (ND6). The ND6 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variations in the human MT-ND6 gene are associated…

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7.1.1.2
↗
Aliases
ND6, MTMT-NADH dehydrogenase, subunit 6 (complex I), NADH dehydrogenase subunit 6
Band
n/a
Bgee
gastric mucosa · left uterine tube · right uterine tube · right auricle of heart · granulocyte
BioGPS
n/a
Chr.
Mitochondrial DNA (human) · Mitochondrial DNA (mouse)

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MT-ND6

Nodes41
Edges40
Triples132
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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MT-ND6

Top relations

Bgee · 20
MT-ND6 → adrenal gland, amygdala, bone marrow, caudate nucleus, cerebellar cortex, fundus, gastric mucosa, granulocyte, hippocampus proper, human kidney, hypothalamus, left uterine tube, neural layer of retina, nucleus accumbens, primary visual cortex, putamen, right auricle of heart, right uterine tube, striatum of neuraxis, superior frontal gyrus
RNA expression pattern · 20
MT-ND6 → adrenal gland, amygdala, bone marrow, caudate nucleus, cerebellar cortex, fundus, gastric mucosa, granulocyte, hippocampus proper, human kidney, hypothalamus, left uterine tube, neural layer of retina, nucleus accumbens, primary visual cortex, putamen, right auricle of heart, right uterine tube, striatum of neuraxis, superior frontal gyrus
related to Clinical significance · 20
MT-ND6 → Additional, Affected, ATP, Complex, French Canadian, Heart, It, Leber, Leber's, Leigh, Leigh's, LHON, NADH, NADH-ubiquinone, Researchers, ROS, The T14484C, These, This, This MT-ND6 G14459A
related to Structure · 14
MT-ND6 → Also, Complex, DNA, L-shaped, L-strand, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, NADH, The, The MT-ND6
Gene ontology · 13
MT-ND6 → integral component of membrane, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial membranes, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, oxidoreductase activity, respirasome, response to cocaine, response to hydrogen peroxide, response to nicotine
related to Function · 11
MT-ND6 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, Initially, NADH, Q10, The, The MT-ND6
related to External links · 7
MT-ND6 → COPaKB, GeneReviews/NCBI/NIH/UW, Mass, Medicine, Mitochondrial DNA-Associated Leigh Syndrome, NARP This, United States National Library
related to Interactions · 4
MT-ND6 → ATP-dependent, NADH, NDUFS3, YME1L1
Chr. · 2
MT-ND6 → Mitochondrial DNA (human), Mitochondrial DNA (mouse)
End · 2
MT-ND6 → 14,070 bp, 14,673 bp

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Important terminology

gene mitochondrial nadh human protein complex ubiquinone bp chain mutation dehydrogenase chr band people dna also optic lhon nd6 syndrome

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MT-ND67.1.1.2↗1.00infobox
MT-ND6AliasesND6, MTMT-NADH dehydrogenase, subunit 6 (complex I), NADH dehydrogenase subunit 61.00infobox
MT-ND6Bandn/a1.00infobox
MT-ND6Bgeegastric mucosa1.00infobox
MT-ND6Bgeeleft uterine tube1.00infobox
MT-ND6Bgeeright uterine tube1.00infobox
MT-ND6Bgeeright auricle of heart1.00infobox
MT-ND6Bgeegranulocyte1.00infobox
MT-ND6Bgeenucleus accumbens1.00infobox
MT-ND6Bgeeputamen1.00infobox
MT-ND6Bgeecaudate nucleus1.00infobox
MT-ND6Bgeeamygdala1.00infobox
MT-ND6Bgeefundus1.00infobox
MT-ND6Bgeeneural layer of retina1.00infobox
MT-ND6Bgeeadrenal gland1.00infobox
MT-ND6Bgeehypothalamus1.00infobox
MT-ND6Bgeestriatum of neuraxis1.00infobox
MT-ND6Bgeebone marrow1.00infobox
MT-ND6Bgeehippocampus proper1.00infobox
MT-ND6Bgeesuperior frontal gyrus1.00infobox
MT-ND6Bgeehuman kidney1.00infobox
MT-ND6Bgeecerebellar cortex1.00infobox
MT-ND6Bgeeprimary visual cortex1.00infobox
MT-ND6BioGPSn/a1.00infobox
MT-ND6Chr.Mitochondrial DNA (human)1.00infobox
MT-ND6Chr.Mitochondrial DNA (mouse)1.00infobox
MT-ND6DatabasesNCBI: entry; OMA: entry1.00infobox
MT-ND6End14,673 bp1.00infobox
MT-ND6End14,070 bp1.00infobox
MT-ND6EnsemblENSG000001986951.00infobox

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