XC-101

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Overview

Non-selective Serotonin receptor modulator Migraine Orally Agonist

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Key facts & relationships

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Drug class: Serotonin 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, and 5-HT7 receptor agonist; Serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonist; Antimigraine agent
Elimination half-life: 10–15 hours
Onset of action: 2–3 hours (TmaxTooltip time to peak levels)
Other names: XC101; XC101-D13H; XC-101-D13H
Routes of administration: Oral

Topics to explore

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Overview

Non-selective Binding selectivity
Serotonin receptor modulator
Migraine
Orally Oral administration
Agonist
Serotonin
5-HT1A 5-HT1A receptor
5-HT1B 5-HT1B receptor
5-HT1D 5-HT1D receptor
5-HT1F 5-HT1F receptor
5-HT7 receptors 5-HT7 receptor
Antagonist Receptor antagonist
5-HT2A 5-HT2A receptor
5-HT2B 5-HT2B receptor
5-HT2C receptors 5-HT2C receptor
Potencies Potency (pharmacology)
Targets Biological target
Antimigraine
Efficacy
Α1A-adrenergic receptor Alpha-1A adrenergic receptor
Adverse effects Adverse effect
Toxicity
Hallucinogenic Hallucinogen
Cardiac fibrosis
Valvulopathy Cardiac valvulopathy
Vasoconstriction
Pharmacokinetics
Tolerability
Ergoline Substituted ergoline
Antimigraine agents Antimigraine agent

Advanced semantic analysis

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Map overview Semantic statistics

Nodes47

Edges46

Triples6

Avg. degree1.96

Density0.042553

Components1

How this topic connects Entity context

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XC-101

Top relations

Drug class · 1

XC-101 → Serotonin 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, and 5-HT7 receptor agonist; Serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonist; Antimigraine agent

Elimination half-life · 1

XC-101 → 10–15 hours

Onset of action · 1

XC-101 → 2–3 hours (TmaxTooltip time to peak levels)

Other names · 1

XC-101 → XC101; XC101-D13H; XC-101-D13H

Routes of administration · 1

XC-101 → Oral

is a · 1

XC-101 → silent antagonist of the receptor

Important terminology Word statistics

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Important terminology

serotonin receptor methysergide 5-ht2b agonist antagonist 5-ht2a antimigraine migraine also prevention 5-ht1b 5-ht1d due effects xc101-d13h drug 5-ht2c xoc pharmaceuticals

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
XC-101	Drug class	Serotonin 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, and 5-HT7 receptor agonist; Serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptor antagonist; Antimigraine agent	1.00	infobox
XC-101	Elimination half-life	10–15 hours	1.00	infobox
XC-101	Onset of action	2–3 hours (TmaxTooltip time to peak levels)	1.00	infobox
XC-101	Other names	XC101; XC101-D13H; XC-101-D13H	1.00	infobox
XC-101	Routes of administration	Oral	1.00	infobox
XC-101	is a	silent antagonist of the receptor	0.90	text

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