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LPAR2: Evolution, Interactions & Overview

Lysophosphatidic acid receptor 2 also known as LPA2 is a protein that in humans is encoded by the LPAR2 gene. LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Language: English [EN]
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LPAR2 topic overview

The analysis highlights Evolution, Interactions and Overview as prominent areas in the source structure around LPAR2.

Related topics
25
Source areas
3
Connected nodes
28
Extracted relationships
75
Concept neighborhoods
6
Bridge connections
28

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Evolution · 19 topics
Overview · 4 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
LPAR2, EDG-4, EDG4, LPA-2, LPA2, lysophosphatidic acid receptor 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4P0C
Band
19p13.11 · 8 B3.3|8 33.91 cM
Bgee
ganglionic eminence · ventricular zone · granulocyte · blood · right testis
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 8 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Evolution

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How LPAR2 connects Entity context

The extracted context around LPAR2 shows recurring relationship patterns in the source. For example, LPAR2 → blood, epiblast, ganglion of vagus nerve, ganglionic eminence, genital tubercle, granulocyte, left testis, monocyte, mucosa of transverse colon, otic vesicle, placenta, primitive streak, right lung, right testis, spleen, tail of embryo, ventricular zone, yolk sac Another extracted example is LPAR2 → activation of phospholipase C activity, cell surface, endocytic vesicle, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, lipid binding, lysophosphatidic acid receptor activity, membrane, plasma membrane, positive regulation of cytosolic calcium ion concentration, protein binding, signal transducer activity, signal transduction. Use these groups to spot repeated connection types before inspecting the individual relationships.

LPAR2

Top relations

Bgee · 18
LPAR2 → blood, epiblast, ganglion of vagus nerve, ganglionic eminence, genital tubercle, granulocyte, left testis, monocyte, mucosa of transverse colon, otic vesicle, placenta, primitive streak, right lung, right testis, spleen, tail of embryo, ventricular zone, yolk sac
RNA expression pattern · 18
LPAR2 → blood, epiblast, ganglion of vagus nerve, ganglionic eminence, genital tubercle, granulocyte, left testis, monocyte, mucosa of transverse colon, otic vesicle, placenta, primitive streak, right lung, right testis, spleen, tail of embryo, ventricular zone, yolk sac
Gene ontology · 15
LPAR2 → activation of phospholipase C activity, cell surface, endocytic vesicle, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, lipid binding, lysophosphatidic acid receptor activity, membrane, plasma membrane, positive regulation of cytosolic calcium ion concentration, protein binding, signal transducer activity, signal transduction
Band · 2
LPAR2 → 19p13.11, 8 B3.3|8 33.91 cM
Chr. · 2
LPAR2 → Chromosome 19 (human), Chromosome 8 (mouse)
End · 2
LPAR2 → 19,628,930 bp, 70,283,752 bp
Aliases · 1
LPAR2 → LPAR2, EDG-4, EDG4, LPA-2, LPA2, lysophosphatidic acid receptor 2
Available structures · 1
LPAR2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4P0C
BioGPS · 1
LPAR2 → More reference expression data
Databases · 1
LPAR2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor bp lysophosphatidic acid gene chr human band lpa2 chromosome 19 protein protein-coupled location receptors also mouse lipid signaling function

LPAR2 relationships Subject–Predicate–Object triples

TTTA extracted 75 structured relationships around LPAR2. Examples in this analysis include LPAR2 → Aliases → LPAR2, EDG-4, EDG4, LPA-2, LPA2, lysophosphatidic acid receptor 2 and LPAR2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4P0C. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
LPAR2AliasesLPAR2, EDG-4, EDG4, LPA-2, LPA2, lysophosphatidic acid receptor 21.00infobox
LPAR2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4P0C1.00infobox
LPAR2Band19p13.111.00infobox
LPAR2Band8 B3.3|8 33.91 cM1.00infobox
LPAR2Bgeeganglionic eminence1.00infobox
LPAR2Bgeeventricular zone1.00infobox
LPAR2Bgeegranulocyte1.00infobox
LPAR2Bgeeblood1.00infobox
LPAR2Bgeeright testis1.00infobox
LPAR2Bgeespleen1.00infobox
LPAR2Bgeeleft testis1.00infobox
LPAR2Bgeemonocyte1.00infobox
LPAR2Bgeemucosa of transverse colon1.00infobox
LPAR2Bgeeright lung1.00infobox
LPAR2Bgeeyolk sac1.00infobox
LPAR2Bgeeepiblast1.00infobox
LPAR2Bgeetail of embryo1.00infobox
LPAR2Bgeeotic vesicle1.00infobox
LPAR2Bgeegenital tubercle1.00infobox
LPAR2Bgeeganglion of vagus nerve1.00infobox
LPAR2Bgeeprimitive streak1.00infobox
LPAR2Bgeeplacenta1.00infobox
LPAR2BioGPSMore reference expression data1.00infobox
LPAR2Chr.Chromosome 19 (human)1.00infobox
LPAR2Chr.Chromosome 8 (mouse)1.00infobox
LPAR2DatabasesNCBI: entry; OMA: entry1.00infobox
LPAR2End19,628,930 bp1.00infobox
LPAR2End70,283,752 bp1.00infobox
LPAR2EnsemblENSG000000645471.00infobox
LPAR2Entrez91701.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around LPAR2 bring nearby vocabulary together. In this analysis, examples include Gene, Function and Lysophosphatidic. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Chromosome
    • Human
    • Lpar2
    • B3
    • Bp
    • Chr
    • End
    • Function
    • Lysophosphatidic
    • Mouse
    • Search
  • lysophosphatidic acid
    • Lysophosphatidic
    • Receptor
    • Protein
    • Gene
    • Lpa2
    • Lpar2
    • Also
    • Cellular
    • Function
    • Lipid
    • Lpa
    • Protein-coupled
  • LPAR2
    • Gene
    • Function
    • Lysophosphatidic
    • Search
    • Receptor
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • External
  • lpar2
    • Gene
    • Function
    • Lysophosphatidic
    • Search
    • Receptor
    • Location
    • Protein
    • Chromosome
    • Human
    • Bp
    • Chr
    • External
  • protein
    • Cellular
    • Proteins
    • Receptor
    • B3
    • End
    • Function
    • Ion
    • Lipid
    • Lpa
    • Mouse
    • Protein-coupled
    • Search
  • g protein-coupled receptor
    • Signaling
    • B3
    • Cellular
    • End
    • Function
    • Ion
    • Mouse
    • Proteins
    • Receptor
    • Search
    • Location
    • Chromosome

Connections between topic areas Semantic bridges

For LPAR2, one of the stronger structural bridges in this analysis connects LPAR2 with Evolution. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
LPAR2Evolution · splits 9 ⟂ 20
LPAR2Overview · splits 24 ⟂ 5
LPAR2Interactions · splits 26 ⟂ 3

Map overview Semantic statistics

LPAR2

Nodes29
Edges28
Triples75
Avg. degree1.93
Density0.068966
Components1

Source & methodology

TTTA analyzes the structure around LPAR2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Evolution, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — LPAR2 · EN edition · Analysis: TopicsToTalkAbout

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