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GPR3: Function, Evolution & Overview

G-protein coupled receptor 3 is a protein that in humans is encoded by the GPR3 gene. The protein encoded by this gene is a member of the G protein-coupled receptor family of transmembrane receptors and is involved in signal transduction.

Language: English [EN]
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GPR3 topic overview

The analysis highlights Function, Evolution and Overview as prominent areas in the source structure around GPR3.

Related topics
43
Source areas
3
Connected nodes
46
Extracted relationships
86
Concept neighborhoods
16
Bridge connections
46

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 18 topics
Evolution · 17 topics
Overview · 8 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GPR3, ACCA, G protein-coupled receptor 3
Band
1p36.11 · 4|4 D2.3
Bgee
secondary oocyte · testicle · prefrontal cortex · cingulate gyrus · anterior cingulate cortex
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Evolution

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GPR3 connects Entity context

The extracted context around GPR3 shows recurring relationship patterns in the source. For example, GPR3 → anterior cingulate cortex, cingulate gyrus, embryo, facial motor nucleus, islet of Langerhans, morula, prefrontal cortex, primary oocyte, primary visual cortex, right auricle of heart, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, testicle, zygote Another extracted example is GPR3 → adenylate cyclase-activating G protein-coupled receptor signaling pathway, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, membrane, plasma membrane, positive regulation of cold-induced thermogenesis, protein binding, regulation of meiotic nuclear division, signal transducer activity, signal transduction. Use these groups to spot repeated connection types before inspecting the individual relationships.

GPR3

Top relations

Bgee · 16
GPR3 → anterior cingulate cortex, cingulate gyrus, embryo, facial motor nucleus, islet of Langerhans, morula, prefrontal cortex, primary oocyte, primary visual cortex, right auricle of heart, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, testicle, zygote
RNA expression pattern · 16
GPR3 → anterior cingulate cortex, cingulate gyrus, embryo, facial motor nucleus, islet of Langerhans, morula, prefrontal cortex, primary oocyte, primary visual cortex, right auricle of heart, right frontal lobe, right hemisphere of cerebellum, secondary oocyte, superior frontal gyrus, testicle, zygote
Gene ontology · 13
GPR3 → adenylate cyclase-activating G protein-coupled receptor signaling pathway, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, membrane, plasma membrane, positive regulation of cold-induced thermogenesis, protein binding, regulation of meiotic nuclear division, signal transducer activity, signal transduction
related to Function · 9
GPR3 → Alternatively, GPR12, GPR6, Gs, It, S1P, SPC, This, Various
related to Reproductive system · 5
GPR3 → In, It, That GPR3, The, When
related to Brain cells · 3
GPR3 → Alzheimer's, In, Notably
related to Evolution · 3
GPR3 → GPR6GPR12S1PR5LPAR2S1PR1S1PR2LPAR3LPAR1CNR1S1PR3MC3RMC4RS1PR4MC5RMC1RCNR2MC2RGPR119, Paralogues, The
Band · 2
GPR3 → 1p36.11, 4|4 D2.3
Chr. · 2
GPR3 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
GPR3 → 132,939,847 bp, 27,395,814 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor protein gene expression bp expressed neurons mrna chr human band thermogenic camp receptors brown tissue oocytes overexpression protein-coupled chromosome

GPR3 relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around GPR3. Examples in this analysis include GPR3 → Aliases → GPR3, ACCA, G protein-coupled receptor 3 and GPR3 → Band → 1p36.11. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GPR3AliasesGPR3, ACCA, G protein-coupled receptor 31.00infobox
GPR3Band1p36.111.00infobox
GPR3Band4|4 D2.31.00infobox
GPR3Bgeesecondary oocyte1.00infobox
GPR3Bgeetesticle1.00infobox
GPR3Bgeeprefrontal cortex1.00infobox
GPR3Bgeecingulate gyrus1.00infobox
GPR3Bgeeanterior cingulate cortex1.00infobox
GPR3Bgeeright frontal lobe1.00infobox
GPR3Bgeeright hemisphere of cerebellum1.00infobox
GPR3Bgeeislet of Langerhans1.00infobox
GPR3Bgeeprimary visual cortex1.00infobox
GPR3Bgeeright auricle of heart1.00infobox
GPR3Bgeezygote1.00infobox
GPR3Bgeeprimary oocyte1.00infobox
GPR3Bgeefacial motor nucleus1.00infobox
GPR3Bgeesuperior frontal gyrus1.00infobox
GPR3Bgeeembryo1.00infobox
GPR3Bgeemorula1.00infobox
GPR3BioGPSMore reference expression data1.00infobox
GPR3Chr.Chromosome 1 (human)1.00infobox
GPR3Chr.Chromosome 4 (mouse)1.00infobox
GPR3DatabasesNCBI: entry; OMA: entry1.00infobox
GPR3End27,395,814 bp1.00infobox
GPR3End132,939,847 bp1.00infobox
GPR3EnsemblENSG000001817731.00infobox
GPR3Entrez28271.00infobox
GPR3External IDsOMIM: 600241; MGI: 101908; GeneCards: GPR31.00infobox
GPR3Gene location (Human)Gene location (Human)Chr.Chromosome 1 (human)Band1p36.11Start27,392,622 bpEnd27,395,814 bp1.00infobox
GPR3Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 4 (mouse)Band4|4 D2.3Start132,936,651 bpEnd132,939,847 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GPR3 bring nearby vocabulary together. In this analysis, examples include Expression, Expressed and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GPR3
    • Expression
    • Expressed
    • Receptor
    • Mrna
    • Neurons
    • Overexpression
    • Thermogenic
    • Brain
    • Brown
    • Gene
    • Protein
    • Tissue
  • gpr3
    • Expression
    • Expressed
    • Receptor
    • Mrna
    • Neurons
    • Overexpression
    • Thermogenic
    • Brain
    • Brown
    • Gene
    • Protein
    • Tissue
  • protein
    • Gene
    • Signal
    • Transduction
    • Protein-coupled
    • Receptor
    • Neurons
    • Cerebellum
    • Cortex
    • Gpr3
    • Location
    • Band
    • Brain
  • gene
    • Location
    • Chromosome
    • Human
    • Protein-coupled
    • Bp
    • Chr
    • Receptor
    • Protein
    • Signal
    • Transduction
    • Band
    • Mouse
  • g protein-coupled receptor
    • Receptor
    • Location
    • Signal
    • Transduction
    • Chromosome
    • Human
    • Bp
    • Chr
    • Ligand
    • Cannabidiol
    • Cerebellum
    • Cortex
  • signal transduction
    • Signal
    • Transduction
    • Protein-coupled
    • Receptor
    • Gene
    • Protein
    • Cerebellum
    • Cortex
    • Location
    • Band
    • Chromosome
    • Human
  • brown adipose tissue
    • Adipose
    • Brown
    • Tissue
    • Bat
    • Thermogenic
    • Brain
    • Overexpression
    • Gene
    • Expression
    • Cannabidiol
    • Location
    • Chloride
  • ligand
    • Signaling
    • Receptor
    • Location
    • Signal
    • Transduction
    • Constitutive
    • Meiotic
    • Mouse
    • Protein-coupled
    • Mrna
    • Oocytes
    • Protein

Connections between topic areas Semantic bridges

For GPR3, one of the stronger structural bridges in this analysis connects GPR3 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GPR3Function · splits 28 ⟂ 19
GPR3Evolution · splits 29 ⟂ 18
GPR3Overview · splits 38 ⟂ 9

Map overview Semantic statistics

GPR3

Nodes47
Edges46
Triples86
Avg. degree1.96
Density0.042553
Components1

Source & methodology

TTTA analyzes the structure around GPR3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Evolution & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GPR3 · EN edition · Analysis: TopicsToTalkAbout

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