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Lysophosphatidic acid receptor 1 also known as LPA1 is a protein that in humans is encoded by the LPAR1 gene. LPA1 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).
The analysis highlights Evolution, Cancer and Function as prominent areas in the source structure around LPAR1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around LPAR1 shows recurring relationship patterns in the source. For example, LPAR1 → activation of phospholipase C activity, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, bleb assembly, brain development, cell chemotaxis, cell surface, cellular response to 1-oleoyl-sn-glycerol 3-phosphate, cellular response to oxygen levels, cerebellum development, corpus callosum development, cytoplasm, dendritic shaft, dendritic spine, endocytic vesicle, endosome, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, G-protein alpha-subunit binding, integral component of membrane, integral component of plasma membrane Another extracted example is LPAR1 → autopod region, calvaria, conjunctival fornix, decidua, foot, hand, mandibular prominence, maxillary prominence, optic nerve, utricle. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
receptor gene lysophosphatidic acid receptors bp lpa1 protein protein-coupled signaling chr lpa also mouse band lipid function external known encoded
TTTA extracted 90 structured relationships around LPAR1. Examples in this analysis include LPAR1 → Aliases → LPAR1, receptor 1, lysophosphatidic acid receptor 1 and LPAR1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4Z34, 4Z35, 4Z36. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| LPAR1 | Aliases | LPAR1, receptor 1, lysophosphatidic acid receptor 1 | 1.00 | infobox |
| LPAR1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4Z34, 4Z35, 4Z36 | 1.00 | infobox |
| LPAR1 | Band | 4 B3|4 32.2 cM | 1.00 | infobox |
| LPAR1 | Bgee | maxillary prominence | 1.00 | infobox |
| LPAR1 | Bgee | calvaria | 1.00 | infobox |
| LPAR1 | Bgee | mandibular prominence | 1.00 | infobox |
| LPAR1 | Bgee | optic nerve | 1.00 | infobox |
| LPAR1 | Bgee | autopod region | 1.00 | infobox |
| LPAR1 | Bgee | hand | 1.00 | infobox |
| LPAR1 | Bgee | foot | 1.00 | infobox |
| LPAR1 | Bgee | decidua | 1.00 | infobox |
| LPAR1 | Bgee | conjunctival fornix | 1.00 | infobox |
| LPAR1 | Bgee | utricle | 1.00 | infobox |
| LPAR1 | BioGPS | More reference expression data | 1.00 | infobox |
| LPAR1 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| LPAR1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| LPAR1 | End | 58,553,898 bp | 1.00 | infobox |
| LPAR1 | Ensembl | ENSG00000198121 | 1.00 | infobox |
| LPAR1 | Entrez | 1902 | 1.00 | infobox |
| LPAR1 | External IDs | OMIM: 602282; MGI: 108429; GeneCards: LPAR1 | 1.00 | infobox |
| LPAR1 | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 4 (mouse)Band4 B3|4 32.2 cMStart58,435,255 bpEnd58,553,898 bp | 1.00 | infobox |
| LPAR1 | Gene ontology | lysophosphatidic acid binding | 1.00 | infobox |
| LPAR1 | Gene ontology | PDZ domain binding | 1.00 | infobox |
| LPAR1 | Gene ontology | G protein-coupled receptor activity | 1.00 | infobox |
| LPAR1 | Gene ontology | signal transducer activity | 1.00 | infobox |
| LPAR1 | Gene ontology | protein binding | 1.00 | infobox |
| LPAR1 | Gene ontology | lysophosphatidic acid receptor activity | 1.00 | infobox |
| LPAR1 | Gene ontology | G-protein alpha-subunit binding | 1.00 | infobox |
| LPAR1 | Gene ontology | phospholipid binding | 1.00 | infobox |
| LPAR1 | Gene ontology | lipid binding | 1.00 | infobox |
The concept neighborhoods around LPAR1 bring nearby vocabulary together. In this analysis, examples include Gene, Lysophosphatidic and B3. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For LPAR1, one of the stronger structural bridges in this analysis connects LPAR1 with Evolution. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around LPAR1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Evolution, Cancer & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — LPAR1 · EN edition · Analysis: TopicsToTalkAbout