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Loop diuretic

Loop diuretics are drugs that are often used for the treatment of hypertension and edema secondary to congestive heart failure, liver cirrhosis, or chronic kidney disease. Their effect, like all diuretics, is to cause the body to excrete more water in the urine. Loop diuretics are more effective than thiazide diuretics in patients with impaired kidney…

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ATC code
C03C
Biological target
Na-K-Cl cotransporter
MeSH
D049994
Synonyms
High ceiling diuretic
Use
congestive heart failure, nephrotic syndrome, cirrhosis, hypertension, edema

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Overview

Mechanism of action

Pharmacokinetics

Clinical use

Resistance

Adverse effects

Examples

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Map overview Semantic statistics

Loop diuretic

Nodes82
Edges81
Triples65
Avg. degree1.98
Density0.02439
Components1

How this topic connects Entity context

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Loop diuretic

Top relations

related to Clinical use · 23
Loop diuretic → According, After, Cardiology, Cochrane Hypertension, Creatinine, Edema, ESC, European Society, For, Frequent, Giving, Heart, However, Hypertension, JNC-8, Joint National Committee, Loop, Meanwhile, Pulmonary, Slow
related to Mechanism of action · 15
Loop diuretic → ABCC4, Absorption, At, By, Cl, GFR, Henle, Loop, Na, NKCC2, OAT-1, OAT-2, The, This, Without
related to Resistance · 15
Loop diuretic → After, Chronic, CKD, Diuretic, Increase, Nephron, Non-steroidal, NSAID, Other, Prolonged, There, These, Thiazide, This, Those
has effect · 3
Loop diuretic → ADRs, Common ADRs, The
related to Pharmacokinetics · 3
Loop diuretic → Also, Loop, The
ATC code · 1
Loop diuretic → C03C
Biological target · 1
Loop diuretic → Na-K-Cl cotransporter
MeSH · 1
Loop diuretic → D049994
Synonyms · 1
Loop diuretic → High ceiling diuretic
Use · 1
Loop diuretic → congestive heart failure, nephrotic syndrome, cirrhosis, hypertension, edema

Important terminology Word statistics

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Important terminology

diuretics loop furosemide diuretic kidney sodium resistance failure edema also dose heart use needed patients bumetanide hypertension magnesium absorption fluid

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Loop diureticATC codeC03C1.00infobox
Loop diureticBiological targetNa-K-Cl cotransporter1.00infobox
Loop diureticMeSHD0499941.00infobox
Loop diureticSynonymsHigh ceiling diuretic1.00infobox
Loop diureticUsecongestive heart failure, nephrotic syndrome, cirrhosis, hypertension, edema1.00infobox
Loop diuretichas effectThe0.60section
Loop diuretichas effectADRs0.60section
Loop diuretichas effectCommon ADRs0.60section
Loop diureticrelated to Clinical useLoop0.60section
Loop diureticrelated to Clinical useHeart0.60section
Loop diureticrelated to Clinical useGiving0.60section
Loop diureticrelated to Clinical useHowever0.60section

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    Min side: 3
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