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ROMK

The renal outer medullary potassium channel (ROMK) is an ATP-dependent potassium channel (Kir1.1) that transports potassium out of cells. It plays an important role in potassium recycling in the thick ascending limb (TAL) and potassium secretion in the cortical collecting duct (CCD) of the nephron. In humans, ROMK is encoded by the KCNJ1 (potassium…

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Aliases
KCNJ1, KIR1.1, ROMK, ROMK1, potassium voltage-gated channel subfamily J member 1, potassium inwardly rectifying channel subfamily J member 1
Band
11q24.3 · 9|9 A4
Bgee
renal medulla · kidney tubule · glomerulus · metanephric glomerulus · human kidney
BioGPS
n/a
Chr.
Chromosome 11 (human) · Chromosome 9 (mouse)
Databases
NCBI: entry; OMA: entry

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Map overview Semantic statistics

ROMK

Nodes22
Edges21
Triples92
Avg. degree1.91
Density0.090909
Components1

How this topic connects Entity context

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ROMK

Top relations

Bgee · 19
ROMK → connecting tubule, convoluted tubule, cortical collecting duct, distal tubule, epithelium of colon, glomerulus, human kidney, inner renal medulla, inner stripe of outer renal medulla, kidney tubule, metanephric glomerulus, nucleus accumbens, olfactory epithelium, outer stripe of outer renal medulla, putamen, renal medulla, right kidney, tail of epididymis, testicle
RNA expression pattern · 19
ROMK → connecting tubule, convoluted tubule, cortical collecting duct, distal tubule, epithelium of colon, glomerulus, human kidney, inner renal medulla, inner stripe of outer renal medulla, kidney tubule, metanephric glomerulus, nucleus accumbens, olfactory epithelium, outer stripe of outer renal medulla, putamen, renal medulla, right kidney, tail of epididymis, testicle
Gene ontology · 15
ROMK → ATP binding, ATP-activated inward rectifier potassium channel activity, excretion, integral component of membrane, inward rectifier potassium channel activity, ion transport, membrane, nucleotide binding, phosphatidylinositol-4,5-bisphosphate binding, plasma membrane, potassium ion import across plasma membrane, potassium ion transport, regulation of ion transmembrane transport, voltage-gated ion channel activity, voltage-gated potassium channel complex
related to External links · 8
ROMK → Medicine, Medicine Medical Subject Headings, MeSH, National Library, NDI, ROMK1, This, United States National Library
related to Function · 6
ROMK → ATP, ATP-sensitive, It, Klotho, Potassium, The
related to Role in hypokalemia and magnesium deficiency · 5
ROMK → Conversely, In, Sgk1, The ROMK, This
Band · 2
ROMK → 11q24.3, 9|9 A4
Chr. · 2
ROMK → Chromosome 11 (human), Chromosome 9 (mouse)
End · 2
ROMK → 128,867,373 bp, 32,310,493 bp
Aliases · 1
ROMK → KCNJ1, KIR1.1, ROMK, ROMK1, potassium voltage-gated channel subfamily J member 1, potassium inwardly rectifying channel subfamily J member 1

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Important terminology

potassium gene channel bp human chr band chromosome 11 magnesium role kcnj1 protein location encoded hypokalemia deficiency mouse renal outer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ROMKAliasesKCNJ1, KIR1.1, ROMK, ROMK1, potassium voltage-gated channel subfamily J member 1, potassium inwardly rectifying channel subfamily J member 11.00infobox
ROMKBand11q24.31.00infobox
ROMKBand9|9 A41.00infobox
ROMKBgeerenal medulla1.00infobox
ROMKBgeekidney tubule1.00infobox
ROMKBgeeglomerulus1.00infobox
ROMKBgeemetanephric glomerulus1.00infobox
ROMKBgeehuman kidney1.00infobox
ROMKBgeetesticle1.00infobox
ROMKBgeenucleus accumbens1.00infobox
ROMKBgeeepithelium of colon1.00infobox
ROMKBgeeputamen1.00infobox
ROMKBgeetail of epididymis1.00infobox
ROMKBgeeright kidney1.00infobox
ROMKBgeeinner renal medulla1.00infobox
ROMKBgeedistal tubule1.00infobox
ROMKBgeeinner stripe of outer renal medulla1.00infobox
ROMKBgeeolfactory epithelium1.00infobox
ROMKBgeeconnecting tubule1.00infobox
ROMKBgeeouter stripe of outer renal medulla1.00infobox
ROMKBgeeconvoluted tubule1.00infobox
ROMKBgeecortical collecting duct1.00infobox
ROMKBioGPSn/a1.00infobox
ROMKChr.Chromosome 11 (human)1.00infobox
ROMKChr.Chromosome 9 (mouse)1.00infobox
ROMKDatabasesNCBI: entry; OMA: entry1.00infobox
ROMKEnd128,867,373 bp1.00infobox
ROMKEnd32,310,493 bp1.00infobox
ROMKEnsemblENSG000001517041.00infobox
ROMKEntrez37581.00infobox

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