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PTTG1: Products, Interactions & Overview

Securin is a protein that in humans is encoded by the PTTG1 gene.

Language: English [EN]
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PTTG1 topic overview

The analysis highlights Products, Interactions and Overview as prominent areas in the source structure around PTTG1.

Related topics
8
Source areas
2
Connected nodes
10
Extracted relationships
89
Concept neighborhoods
4
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 6 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PTTG1, EAP1, HPTTG, PTTG, TUTR1, pituitary tumor-transforming 1, PTTG1 regulator of sister chromatid separation, securin, ECRAR
Band
5q33.3 · 11|11 B1.1
Bgee
secondary oocyte · ventricular zone · left testis · ganglionic eminence · right testis
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PTTG1 connects Entity context

The extracted context around PTTG1 shows recurring relationship patterns in the source. For example, PTTG1 → anaphase-promoting complex-dependent catabolic process, cell cycle, cell division, cellular response to DNA damage stimulus, chromosome organization, chromosome segregation, cysteine-type endopeptidase inhibitor activity, cytoplasm, cytosol, DNA repair, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, homologous chromosome segregation, negative regulation of endopeptidase activity, negative regulation of mitotic sister chromatid separation, negative regulation of peptidase activity, nucleus, peptidase inhibitor activity, protein binding, regulation of transcription by RNA polymerase II Another extracted example is PTTG1 → ankle, blood, bone marrow, ciliary body, ganglionic eminence, gingival epithelium, iris, left testis, mucosa of esophagus, otic placode, primary oocyte, primitive streak, retinal pigment epithelium, right testis, secondary oocyte, sperm, trabecular bone, ventricular zone, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

PTTG1

Top relations

Gene ontology · 25
PTTG1 → anaphase-promoting complex-dependent catabolic process, cell cycle, cell division, cellular response to DNA damage stimulus, chromosome organization, chromosome segregation, cysteine-type endopeptidase inhibitor activity, cytoplasm, cytosol, DNA repair, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, homologous chromosome segregation, negative regulation of endopeptidase activity, negative regulation of mitotic sister chromatid separation, negative regulation of peptidase activity, nucleus, peptidase inhibitor activity, protein binding, regulation of transcription by RNA polymerase II
Bgee · 19
PTTG1 → ankle, blood, bone marrow, ciliary body, ganglionic eminence, gingival epithelium, iris, left testis, mucosa of esophagus, otic placode, primary oocyte, primitive streak, retinal pigment epithelium, right testis, secondary oocyte, sperm, trabecular bone, ventricular zone, zygote
RNA expression pattern · 19
PTTG1 → ankle, blood, bone marrow, ciliary body, ganglionic eminence, gingival epithelium, iris, left testis, mucosa of esophagus, otic placode, primary oocyte, primitive streak, retinal pigment epithelium, right testis, secondary oocyte, sperm, trabecular bone, ventricular zone, zygote
related to Interactions · 3
PTTG1 → DNAJA1, Ku70P53, PTTG1IP
related to Regulation · 3
PTTG1 → During Mitosis CDK1, PHA-848125, Ser-165
Band · 2
PTTG1 → 11|11 B1.1, 5q33.3
Chr. · 2
PTTG1 → Chromosome 11 (mouse), Chromosome 5 (human)
End · 2
PTTG1 → 160,428,739 bp, 43,317,078 bp
Aliases · 1
PTTG1 → PTTG1, EAP1, HPTTG, PTTG, TUTR1, pituitary tumor-transforming 1, PTTG1 regulator of sister chromatid separation, securin, ECRAR
BioGPS · 1
PTTG1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band protein chromosome securin location encoded sister chromatid separation mouse function regulation product 428 739 end

PTTG1 relationships Subject–Predicate–Object triples

TTTA extracted 89 structured relationships around PTTG1. Examples in this analysis include PTTG1 → Aliases → PTTG1, EAP1, HPTTG, PTTG, TUTR1, pituitary tumor-transforming 1, PTTG1 regulator of sister chromatid separation, securin, ECRAR and PTTG1 → Band → 5q33.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PTTG1AliasesPTTG1, EAP1, HPTTG, PTTG, TUTR1, pituitary tumor-transforming 1, PTTG1 regulator of sister chromatid separation, securin, ECRAR1.00infobox
PTTG1Band5q33.31.00infobox
PTTG1Band11|11 B1.11.00infobox
PTTG1Bgeesecondary oocyte1.00infobox
PTTG1Bgeeventricular zone1.00infobox
PTTG1Bgeeleft testis1.00infobox
PTTG1Bgeeganglionic eminence1.00infobox
PTTG1Bgeeright testis1.00infobox
PTTG1Bgeesperm1.00infobox
PTTG1Bgeegingival epithelium1.00infobox
PTTG1Bgeetrabecular bone1.00infobox
PTTG1Bgeebone marrow1.00infobox
PTTG1Bgeemucosa of esophagus1.00infobox
PTTG1Bgeeciliary body1.00infobox
PTTG1Bgeezygote1.00infobox
PTTG1Bgeeretinal pigment epithelium1.00infobox
PTTG1Bgeeprimary oocyte1.00infobox
PTTG1Bgeeiris1.00infobox
PTTG1Bgeeblood1.00infobox
PTTG1Bgeeprimitive streak1.00infobox
PTTG1Bgeeankle1.00infobox
PTTG1Bgeeotic placode1.00infobox
PTTG1BioGPSMore reference expression data1.00infobox
PTTG1Chr.Chromosome 5 (human)1.00infobox
PTTG1Chr.Chromosome 11 (mouse)1.00infobox
PTTG1DatabasesNCBI: entry; OMA: entry1.00infobox
PTTG1End160,428,739 bp1.00infobox
PTTG1End43,317,078 bp1.00infobox
PTTG1EnsemblENSG000001646111.00infobox
PTTG1Entrez92321.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PTTG1 bring nearby vocabulary together. In this analysis, examples include Securin, Chromatid and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PTTG1
    • Securin
    • Chromatid
    • Function
    • Inhibitor
    • Regulation
    • Response
    • Separation
    • Sister
    • Gene
    • Location
    • Chromosome
    • Human
  • pttg1
    • Securin
    • Chromatid
    • Function
    • Inhibitor
    • Regulation
    • Response
    • Separation
    • Sister
    • Gene
    • Location
    • Chromosome
    • Human
  • protein
    • Encoded
    • Domain
    • Nucleus
    • Securin
    • Gene
    • Pttg1
    • Activity
    • Anaphase-promoting
    • B1
    • Chromatid
    • End
    • Expressed
  • gene
    • Location
    • Product
    • Securin
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • Pttg1
    • Activity
    • B1
    • Chromatid

Connections between topic areas Semantic bridges

For PTTG1, one of the stronger structural bridges in this analysis connects PTTG1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PTTG1Interactions · splits 4 ⟂ 7
PTTG1Overview · splits 8 ⟂ 3

Map overview Semantic statistics

PTTG1

Nodes11
Edges10
Triples89
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around PTTG1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Products, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PTTG1 · EN edition · Analysis: TopicsToTalkAbout

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