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PTTG1

Securin is a protein that in humans is encoded by the PTTG1 gene.

Products, Interactions & Overview

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Topic orientation

PTTG1 at a glance

The strongest research directions include Interactions. Use the connected concepts below as starting points, not as a keyword checklist.

InteractDNAJA1Ku70P53PTTG1IPProteinGene

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Explore the main themes, entities and connections around PTTG1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

InteractDNAJA1Ku70P53PTTG1IP
6 related topics

Overview

ProteinGene
2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
PTTG1, EAP1, HPTTG, PTTG, TUTR1, pituitary tumor-transforming 1, PTTG1 regulator of sister chromatid separation, securin, ECRAR
Band
5q33.3 · 11|11 B1.1
Bgee
secondary oocyte · ventricular zone · left testis · ganglionic eminence · right testis
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

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Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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PTTG1

Top relations

Gene ontology · 25
PTTG1 → anaphase-promoting complex-dependent catabolic process, cell cycle, cell division, cellular response to DNA damage stimulus, chromosome organization, chromosome segregation, cysteine-type endopeptidase inhibitor activity, cytoplasm, cytosol, DNA repair, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, homologous chromosome segregation, negative regulation of endopeptidase activity, negative regulation of mitotic sister chromatid separation, negative regulation of peptidase activity, nucleus, peptidase inhibitor activity, protein binding, regulation of transcription by RNA polymerase II
Bgee · 19
PTTG1 → ankle, blood, bone marrow, ciliary body, ganglionic eminence, gingival epithelium, iris, left testis, mucosa of esophagus, otic placode, primary oocyte, primitive streak, retinal pigment epithelium, right testis, secondary oocyte, sperm, trabecular bone, ventricular zone, zygote
RNA expression pattern · 19
PTTG1 → ankle, blood, bone marrow, ciliary body, ganglionic eminence, gingival epithelium, iris, left testis, mucosa of esophagus, otic placode, primary oocyte, primitive streak, retinal pigment epithelium, right testis, secondary oocyte, sperm, trabecular bone, ventricular zone, zygote
related to Interactions · 3
PTTG1 → DNAJA1, Ku70P53, PTTG1IP
related to Regulation · 3
PTTG1 → During Mitosis CDK1, PHA-848125, Ser-165
Band · 2
PTTG1 → 11|11 B1.1, 5q33.3
Chr. · 2
PTTG1 → Chromosome 11 (mouse), Chromosome 5 (human)
End · 2
PTTG1 → 160,428,739 bp, 43,317,078 bp
Aliases · 1
PTTG1 → PTTG1, EAP1, HPTTG, PTTG, TUTR1, pituitary tumor-transforming 1, PTTG1 regulator of sister chromatid separation, securin, ECRAR
BioGPS · 1
PTTG1 → More reference expression data

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

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Important terminology

gene bp chr human band protein chromosome securin location encoded sister chromatid separation mouse function regulation product 428 739 end

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
PTTG1AliasesPTTG1, EAP1, HPTTG, PTTG, TUTR1, pituitary tumor-transforming 1, PTTG1 regulator of sister chromatid separation, securin, ECRAR1.00infobox
PTTG1Band5q33.31.00infobox
PTTG1Band11|11 B1.11.00infobox
PTTG1Bgeesecondary oocyte1.00infobox
PTTG1Bgeeventricular zone1.00infobox
PTTG1Bgeeleft testis1.00infobox
PTTG1Bgeeganglionic eminence1.00infobox
PTTG1Bgeeright testis1.00infobox
PTTG1Bgeesperm1.00infobox
PTTG1Bgeegingival epithelium1.00infobox
PTTG1Bgeetrabecular bone1.00infobox
PTTG1Bgeebone marrow1.00infobox
PTTG1Bgeemucosa of esophagus1.00infobox
PTTG1Bgeeciliary body1.00infobox
PTTG1Bgeezygote1.00infobox
PTTG1Bgeeretinal pigment epithelium1.00infobox
PTTG1Bgeeprimary oocyte1.00infobox
PTTG1Bgeeiris1.00infobox
PTTG1Bgeeblood1.00infobox
PTTG1Bgeeprimitive streak1.00infobox
PTTG1Bgeeankle1.00infobox
PTTG1Bgeeotic placode1.00infobox
PTTG1BioGPSMore reference expression data1.00infobox
PTTG1Chr.Chromosome 5 (human)1.00infobox
PTTG1Chr.Chromosome 11 (mouse)1.00infobox
PTTG1DatabasesNCBI: entry; OMA: entry1.00infobox
PTTG1End160,428,739 bp1.00infobox
PTTG1End43,317,078 bp1.00infobox
PTTG1EnsemblENSG000001646111.00infobox
PTTG1Entrez92321.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

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    Connections between topic areas Semantic bridges

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    Map overview Semantic statistics

    Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

    PTTG1

    Nodes11
    Edges10
    Triples89
    Avg. degree1.82
    Density0.181818
    Components1
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