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Neural cell adhesion molecule: Pathology, Function & Posttranslational modification

Neural cell adhesion molecule (NCAM), also called CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system. Here, the expression of…

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Neural cell adhesion molecule topic overview

The analysis highlights Pathology, Function and Posttranslational modification as prominent areas in the source structure around Neural cell adhesion molecule.

Related topics
56
Source areas
7
Connected nodes
63
Extracted relationships
68
Concept neighborhoods
22
Bridge connections
63

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pathology · 22 topics
Function · 16 topics
Overview · 7 topics
Posttranslational modification · 5 topics
Expression in normal cells · 3 topics
Forms, domains and homophilic binding · 2 topics
Minor exons · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NCAM1, CD56, MSK39, NCAM, neural cell adhesion molecule 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E3V, 2HAZ, 2VKW, 2VKX, 3MTR, 5AEA
Band
11q23.2 · 9 A5.3|9 26.83 cM
Bgee
ventricular zone · ganglionic eminence · middle temporal gyrus · entorhinal cortex · corpus callosum
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 9 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Forms, domains and homophilic binding

Minor exons

  • MW Molecular mass

Posttranslational modification

Expression in normal cells

Function

Pathology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Neural cell adhesion molecule connects Entity context

The extracted context around Neural cell adhesion molecule shows recurring relationship patterns in the source. For example, Neural cell adhesion molecule → ascending aorta, barrel cortex, Brodmann area 46, corpus callosum, endothelial cell, entorhinal cortex, epithelium of lens, fossa, ganglionic eminence, iris, lateral hypothalamus, middle temporal gyrus, neural layer of retina, pons, prefrontal cortex, Rostral migratory stream, substantia nigra, superior frontal gyrus, ventricular zone, ventromedial nucleus Another extracted example is Neural cell adhesion molecule → CAM, CD56, Later, NCAM1, The. Use these groups to spot repeated connection types before inspecting the individual relationships.

Neural cell adhesion molecule

Top relations

Bgee · 20
Neural cell adhesion molecule → ascending aorta, barrel cortex, Brodmann area 46, corpus callosum, endothelial cell, entorhinal cortex, epithelium of lens, fossa, ganglionic eminence, iris, lateral hypothalamus, middle temporal gyrus, neural layer of retina, pons, prefrontal cortex, Rostral migratory stream, substantia nigra, superior frontal gyrus, ventricular zone, ventromedial nucleus
RNA expression pattern · 20
Neural cell adhesion molecule → ascending aorta, barrel cortex, Brodmann area 46, corpus callosum, endothelial cell, entorhinal cortex, epithelium of lens, fossa, ganglionic eminence, iris, lateral hypothalamus, middle temporal gyrus, neural layer of retina, pons, prefrontal cortex, Rostral migratory stream, substantia nigra, superior frontal gyrus, ventricular zone, ventromedial nucleus
related to Expression in normal cells · 5
Neural cell adhesion molecule → CAM, CD56, Later, NCAM1, The
Band · 2
Neural cell adhesion molecule → 11q23.2, 9 A5.3|9 26.83 cM
Chr. · 2
Neural cell adhesion molecule → Chromosome 11 (human), Chromosome 9 (mouse)
End · 2
Neural cell adhesion molecule → 113,278,436 bp, 49,710,225 bp
Aliases · 1
Neural cell adhesion molecule → NCAM1, CD56, MSK39, NCAM, neural cell adhesion molecule 1
Available structures · 1
Neural cell adhesion molecule → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E3V, 2HAZ, 2VKW, 2VKX, 3MTR, 5AEA
BioGPS · 1
Neural cell adhesion molecule → More reference expression data
Databases · 1
Neural cell adhesion molecule → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ncam cd56 cell homophilic binding adhesion neural cells bp neurite human expression chr band outgrowth ncam1 molecule muscle chromosome 11

Neural cell adhesion molecule relationships Subject–Predicate–Object triples

TTTA extracted 68 structured relationships around Neural cell adhesion molecule. Examples in this analysis include Neural cell adhesion molecule → Aliases → NCAM1, CD56, MSK39, NCAM, neural cell adhesion molecule 1 and Neural cell adhesion molecule → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E3V, 2HAZ, 2VKW, 2VKX, 3MTR, 5AEA. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Neural cell adhesion moleculeAliasesNCAM1, CD56, MSK39, NCAM, neural cell adhesion molecule 11.00infobox
Neural cell adhesion moleculeAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2E3V, 2HAZ, 2VKW, 2VKX, 3MTR, 5AEA1.00infobox
Neural cell adhesion moleculeBand11q23.21.00infobox
Neural cell adhesion moleculeBand9 A5.3|9 26.83 cM1.00infobox
Neural cell adhesion moleculeBgeeventricular zone1.00infobox
Neural cell adhesion moleculeBgeeganglionic eminence1.00infobox
Neural cell adhesion moleculeBgeemiddle temporal gyrus1.00infobox
Neural cell adhesion moleculeBgeeentorhinal cortex1.00infobox
Neural cell adhesion moleculeBgeecorpus callosum1.00infobox
Neural cell adhesion moleculeBgeeendothelial cell1.00infobox
Neural cell adhesion moleculeBgeeBrodmann area 461.00infobox
Neural cell adhesion moleculeBgeepons1.00infobox
Neural cell adhesion moleculeBgeesuperior frontal gyrus1.00infobox
Neural cell adhesion moleculeBgeeprefrontal cortex1.00infobox
Neural cell adhesion moleculeBgeeRostral migratory stream1.00infobox
Neural cell adhesion moleculeBgeebarrel cortex1.00infobox
Neural cell adhesion moleculeBgeeepithelium of lens1.00infobox
Neural cell adhesion moleculeBgeesubstantia nigra1.00infobox
Neural cell adhesion moleculeBgeeneural layer of retina1.00infobox
Neural cell adhesion moleculeBgeeventromedial nucleus1.00infobox
Neural cell adhesion moleculeBgeeiris1.00infobox
Neural cell adhesion moleculeBgeefossa1.00infobox
Neural cell adhesion moleculeBgeelateral hypothalamus1.00infobox
Neural cell adhesion moleculeBgeeascending aorta1.00infobox
Neural cell adhesion moleculeBioGPSMore reference expression data1.00infobox
Neural cell adhesion moleculeChr.Chromosome 11 (human)1.00infobox
Neural cell adhesion moleculeChr.Chromosome 9 (mouse)1.00infobox
Neural cell adhesion moleculeDatabasesNCBI: entry; OMA: entry1.00infobox
Neural cell adhesion moleculeEnd113,278,436 bp1.00infobox
Neural cell adhesion moleculeEnd49,710,225 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Neural cell adhesion molecule bring nearby vocabulary together. In this analysis, examples include Adhesion, Cell and Neural. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Neural cell adhesion molecule
    • Adhesion
    • Cell
    • Neural
    • Expression
    • Molecule
    • Ncam1
    • Cells
    • Location
    • Ncam
    • Chromosome
    • Bp
    • Chr
  • neural cell adhesion molecule
    • Adhesion
    • Cell
    • Neural
    • Molecule
    • Expression
    • Ncam1
    • Cd56
    • Cells
    • Location
    • Ncam
    • Binding
    • Chromosome
  • cell collectives
    • Adhesion
    • Neural
    • Molecule
    • Ncam
    • Ncam1
    • Binding
    • Expressed
    • Homophilic
    • Cd56
    • Location
    • Chromosome
    • Bp
  • cell adhesion
    • Adhesion
    • Cell
    • Molecule
    • Neural
    • Ncam1
    • Cd56
    • Ncam
    • Binding
    • Neurons
    • Homophilic
    • Expressed
    • Expression
  • cell-cell adhesion
    • Cell
    • Molecule
    • Neural
    • Ncam1
    • Cd56
    • Binding
    • Neurons
    • Homophilic
    • Expression
    • Muscle
    • Ncam
    • Cells
  • cell-matrix adhesion
    • Cell
    • Molecule
    • Neural
    • Ncam1
    • Cd56
    • Binding
    • Neurons
    • Homophilic
    • Expression
    • Muscle
    • Ncam
    • Cells
  • pancreatic acinar cell carcinoma
    • Adhesion
    • Neural
    • Molecule
    • Ncam
    • Ncam1
    • Binding
    • Expressed
    • Homophilic
    • Cd56
    • Location
    • Chromosome
    • Bp
  • small cell lung carcinoma
    • Adhesion
    • Neural
    • Molecule
    • Ncam
    • Ncam1
    • Binding
    • Expressed
    • Homophilic
    • Cd56
    • Location
    • Chromosome
    • Bp

Connections between topic areas Semantic bridges

For Neural cell adhesion molecule, one of the stronger structural bridges in this analysis connects Neural cell adhesion molecule with Pathology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Neural cell adhesion moleculePathology · splits 41 ⟂ 23
Neural cell adhesion moleculeFunction · splits 47 ⟂ 17
Neural cell adhesion moleculeOverview · splits 56 ⟂ 8
Neural cell adhesion moleculePosttranslational modification · splits 58 ⟂ 6
Neural cell adhesion moleculeExpression in normal cells · splits 60 ⟂ 4
Neural cell adhesion moleculeForms, domains and homophilic binding · splits 61 ⟂ 3

Map overview Semantic statistics

Neural cell adhesion molecule

Nodes64
Edges63
Triples68
Avg. degree1.97
Density0.03125
Components1

Source & methodology

TTTA analyzes the structure around Neural cell adhesion molecule to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Pathology, Function & Posttranslational modification, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Neural cell adhesion molecule · EN edition · Analysis: TopicsToTalkAbout

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