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PRKAA2: Measurement, Function & Overview

5'-AMP-activated protein kinase catalytic subunit alpha-2 is an enzyme that in humans is encoded by the PRKAA2 gene.

Language: English [EN]
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PRKAA2 topic overview

The analysis highlights Measurement, Function and Overview as prominent areas in the source structure around PRKAA2.

Related topics
12
Source areas
2
Connected nodes
14
Extracted relationships
140
Concept neighborhoods
10
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 10 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
2.7.11.27
2.7.11.31
Aliases
PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA, protein kinase AMP-activated catalytic subunit alpha 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2H6D, 2LTU, 2YZA, 3AQV, 4CFE, 4CFF, 4ZHX, 5EZV
Band
1p32.2 · 4|4 C6

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PRKAA2 connects Entity context

The extracted context around PRKAA2 shows recurring relationship patterns in the source. For example, PRKAA2 → [acetyl-CoA carboxylase kinase activity], [hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity], AMP-activated protein kinase activity, ATP binding, autophagy, axon, carnitine shuttle, cellular response to calcium ion, cellular response to glucose starvation, cellular response to glucose stimulus, cellular response to nutrient levels, cellular response to oxidative stress, cellular response to prostaglandin E stimulus, cholesterol biosynthetic process, cholesterol metabolic process, chromatin binding, chromatin organization, cytoplasm, cytoplasmic stress granule, cytosol Another extracted example is PRKAA2 → biceps brachii, body of tongue, Brodmann area 23, digastric muscle, extraocular muscle, knee joint, medial head of gastrocnemius muscle, muscle of thigh, renal medulla, right ventricle, saphenous vein, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, sternocleidomastoid muscle, temporal muscle, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava. Use these groups to spot repeated connection types before inspecting the individual relationships.

PRKAA2

Top relations

Gene ontology · 73
PRKAA2 → [acetyl-CoA carboxylase kinase activity], [hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity], AMP-activated protein kinase activity, ATP binding, autophagy, axon, carnitine shuttle, cellular response to calcium ion, cellular response to glucose starvation, cellular response to glucose stimulus, cellular response to nutrient levels, cellular response to oxidative stress, cellular response to prostaglandin E stimulus, cholesterol biosynthetic process, cholesterol metabolic process, chromatin binding, chromatin organization, cytoplasm, cytoplasmic stress granule, cytosol
Bgee · 20
PRKAA2 → biceps brachii, body of tongue, Brodmann area 23, digastric muscle, extraocular muscle, knee joint, medial head of gastrocnemius muscle, muscle of thigh, renal medulla, right ventricle, saphenous vein, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, sternocleidomastoid muscle, temporal muscle, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava
RNA expression pattern · 20
PRKAA2 → biceps brachii, body of tongue, Brodmann area 23, digastric muscle, extraocular muscle, knee joint, medial head of gastrocnemius muscle, muscle of thigh, renal medulla, right ventricle, saphenous vein, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, sternocleidomastoid muscle, temporal muscle, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle, vena cava
Band · 2
PRKAA2 → 1p32.2, 4|4 C6
Chr. · 2
PRKAA2 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
PRKAA2 → 104,967,087 bp, 56,715,335 bp
2.7.11.1 · 1
PRKAA2 → ↗
2.7.11.27 · 1
PRKAA2 → ↗
2.7.11.31 · 1
PRKAA2 → ↗
Aliases · 1
PRKAA2 → PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA, protein kinase AMP-activated catalytic subunit alpha 2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band protein catalytic subunit kinase chromosome ampk enzyme mouse location amp-activated cellular energy function encoded search

PRKAA2 relationships Subject–Predicate–Object triples

TTTA extracted 140 structured relationships around PRKAA2. Examples in this analysis include PRKAA2 → 2.7.11.1 → ↗ and PRKAA2 → Aliases → PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA, protein kinase AMP-activated catalytic subunit alpha 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PRKAA22.7.11.11.00infobox
PRKAA22.7.11.271.00infobox
PRKAA22.7.11.311.00infobox
PRKAA2AliasesPRKAA2, AMPK, AMPK2, AMPKa2, PRKAA, protein kinase AMP-activated catalytic subunit alpha 21.00infobox
PRKAA2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2H6D, 2LTU, 2YZA, 3AQV, 4CFE, 4CFF, 4ZHX, 5EZV1.00infobox
PRKAA2Band1p32.21.00infobox
PRKAA2Band4|4 C61.00infobox
PRKAA2BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
PRKAA2Bgeebiceps brachii1.00infobox
PRKAA2BgeeSkeletal muscle tissue of biceps brachii1.00infobox
PRKAA2Bgeeright ventricle1.00infobox
PRKAA2Bgeebody of tongue1.00infobox
PRKAA2Bgeerenal medulla1.00infobox
PRKAA2Bgeesaphenous vein1.00infobox
PRKAA2Bgeemuscle of thigh1.00infobox
PRKAA2Bgeevena cava1.00infobox
PRKAA2BgeeBrodmann area 231.00infobox
PRKAA2Bgeetriceps brachii muscle1.00infobox
PRKAA2Bgeemedial head of gastrocnemius muscle1.00infobox
PRKAA2Bgeevastus lateralis muscle1.00infobox
PRKAA2Bgeesternocleidomastoid muscle1.00infobox
PRKAA2Bgeetibialis anterior muscle1.00infobox
PRKAA2Bgeeknee joint1.00infobox
PRKAA2Bgeedigastric muscle1.00infobox
PRKAA2Bgeetemporal muscle1.00infobox
PRKAA2Bgeesoleus muscle1.00infobox
PRKAA2Bgeeextraocular muscle1.00infobox
PRKAA2BioGPSMore reference expression data1.00infobox
PRKAA2Chr.Chromosome 1 (human)1.00infobox
PRKAA2Chr.Chromosome 4 (mouse)1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PRKAA2 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • PRKAA2
    • Protein
    • Gene
    • Activity
    • Amp-activated
    • Function
    • Search
    • Subunit
    • Location
    • Chromosome
    • Human
    • Ampk
    • Bp
  • prkaa2
    • Protein
    • Gene
    • Activity
    • Amp-activated
    • Function
    • Search
    • Subunit
    • Location
    • Chromosome
    • Human
    • Ampk
    • Bp
  • gene
    • Kinase
    • Location
    • Prkaa2
    • Protein
    • Chromosome
    • Human
    • Activity
    • Amp-activated
    • Bp
    • Chr
    • End
    • Function
  • protein
    • Prkaa2
    • Gene
    • Activity
    • Amp-activated
    • Encoded
    • Function
    • Search
    • Subunit
    • Enzyme
    • Location
    • Chromosome
    • Human
  • amp-activated protein kinase
    • Activity
    • Function
    • Prkaa2
    • Protein
    • Search
    • Gene
    • Amp-activated
    • Encoded
    • Kinase
    • Location
    • Catalytic
    • Subunit
  • acetyl-coa carboxylase
    • Acid
    • Carboxylase
    • Cholesterol
    • Fatty
    • Metabolic
    • Reductase
    • Response
    • Cellular
    • Ampk
    • Activity
    • Amp-activated
    • Encoded
  • fatty acid
    • Carboxylase
    • Cholesterol
    • Fatty
    • Metabolic
    • Reductase
    • Response
    • Cellular
    • Ampk
    • Activity
    • Amp-activated
    • Encoded
    • End
  • function
    • Activity
    • Amp-activated
    • Search
    • Kinase
    • Location
    • Prkaa2
    • Protein
    • Chromosome
    • Gene
    • Human
    • Ampk
    • Bp

Connections between topic areas Semantic bridges

For PRKAA2, one of the stronger structural bridges in this analysis connects PRKAA2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
PRKAA2Function · splits 4 ⟂ 11
PRKAA2Overview · splits 12 ⟂ 3

Map overview Semantic statistics

PRKAA2

Nodes15
Edges14
Triples140
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around PRKAA2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PRKAA2 · EN edition · Analysis: TopicsToTalkAbout

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