Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Transient receptor potential cation channel subfamily M (melastatin) member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein that in humans is encoded by the TRPM8 gene. The TRPM8 channel is the primary molecular transducer of cold somatosensation in humans. In addition, mints can desensitize a region through the activation…
The analysis highlights Regions, Ligands and Function as prominent areas in the source structure around TRPM8.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around TRPM8 shows recurring relationship patterns in the source. For example, TRPM8 → calcium channel activity, calcium ion transmembrane transport, calcium ion transport, cation transport, cellular calcium ion homeostasis, detection of temperature stimulus, endoplasmic reticulum, endoplasmic reticulum membrane, external side of plasma membrane, integral component of membrane, ion channel activity, ion transport, membrane, membrane raft, plasma membrane, protein binding, protein homodimerization activity, protein homotetramerization, protein homotrimerization, response to cold Another extracted example is TRPM8 → amniotic fluid, cerebellar cortex, endometrium, gonad, islet of Langerhans, left testis, pancreatic ductal cell, prostate, right lobe of liver, seminiferous tubule, spermatid, spermatocyte, spinal ganglia, testicle, trigeminal ganglion. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
menthol cold receptor channel response agonists receptors protein prostate human bp gene also pain capsaicin cancer chr band stimuli sensitization
TTTA extracted 160 structured relationships around TRPM8. Examples in this analysis include TRPM8 → Aliases → TRPM8, LTRPC6, TRPP8, transient receptor potential cation channel subfamily M member 8, trp-p8, LTrpC-6 and TRPM8 → Band → 2q37.1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| TRPM8 | Aliases | TRPM8, LTRPC6, TRPP8, transient receptor potential cation channel subfamily M member 8, trp-p8, LTrpC-6 | 1.00 | infobox |
| TRPM8 | Band | 2q37.1 | 1.00 | infobox |
| TRPM8 | Band | 1|1 D | 1.00 | infobox |
| TRPM8 | Bgee | right lobe of liver | 1.00 | infobox |
| TRPM8 | Bgee | prostate | 1.00 | infobox |
| TRPM8 | Bgee | testicle | 1.00 | infobox |
| TRPM8 | Bgee | pancreatic ductal cell | 1.00 | infobox |
| TRPM8 | Bgee | trigeminal ganglion | 1.00 | infobox |
| TRPM8 | Bgee | amniotic fluid | 1.00 | infobox |
| TRPM8 | Bgee | islet of Langerhans | 1.00 | infobox |
| TRPM8 | Bgee | gonad | 1.00 | infobox |
| TRPM8 | Bgee | endometrium | 1.00 | infobox |
| TRPM8 | Bgee | left testis | 1.00 | infobox |
| TRPM8 | Bgee | seminiferous tubule | 1.00 | infobox |
| TRPM8 | Bgee | spinal ganglia | 1.00 | infobox |
| TRPM8 | Bgee | spermatid | 1.00 | infobox |
| TRPM8 | Bgee | cerebellar cortex | 1.00 | infobox |
| TRPM8 | Bgee | spermatocyte | 1.00 | infobox |
| TRPM8 | BioGPS | More reference expression data | 1.00 | infobox |
| TRPM8 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| TRPM8 | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| TRPM8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| TRPM8 | End | 234,019,522 bp | 1.00 | infobox |
| TRPM8 | End | 88,317,015 bp | 1.00 | infobox |
| TRPM8 | Ensembl | ENSG00000144481 | 1.00 | infobox |
| TRPM8 | Entrez | 79054 | 1.00 | infobox |
| TRPM8 | External IDs | OMIM: 606678; MGI: 2181435; GeneCards: TRPM8 | 1.00 | infobox |
| TRPM8 | Gene location (Human) | Gene location (Human)Chr.Chromosome 2 (human)Band2q37.1Start233,917,373 bpEnd234,019,522 bp | 1.00 | infobox |
| TRPM8 | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 1 (mouse)Band1|1 DStart88,205,383 bpEnd88,317,015 bp | 1.00 | infobox |
| TRPM8 | Gene ontology | protein homodimerization activity | 1.00 | infobox |
The concept neighborhoods around TRPM8 bring nearby vocabulary together. In this analysis, examples include Shown, Cells and Trpv1. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For TRPM8, one of the stronger structural bridges in this analysis connects TRPM8 with Ligands. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around TRPM8 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Ligands & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — TRPM8 · EN edition · Analysis: TopicsToTalkAbout