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Interferon-lambda receptor: Geography, Function & Location

Interferon-lambda receptor (IFNLR), formerly known as the interleukin-28 receptor (IL28R), is a type II cytokine receptor found largely in epithelial cells. It binds the type III interferons (IFN-λs), which in humans include IFN-λ1 (IL29), IFN-λ2 (IL28A), IFN-λ3 (IL28B), and IFN-λ4. It is a heterodimer of two chains, α (IFNLR1) and β (IL10RB, shared with…

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Interferon-lambda receptor topic overview

The analysis highlights Geography, Function and Location as prominent areas in the source structure around Interferon-lambda receptor.

Related topics
47
Source areas
5
Connected nodes
52
Extracted relationships
33
Concept neighborhoods
18
Bridge connections
52

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 22 topics
Overview · 11 topics
Location · 9 topics
Structure · 4 topics
Regulation · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
IL28RA, CRF2/12, IFNLR, IL-28R1
Domains
InterPro
HGNC
18584
Locus
Chr. 1 p36.11
NCBI gene
163702
OMIM
607404

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Location

Function

Regulation

  • SOCSs Suppressor of cytokine signalling

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Interferon-lambda receptor connects Entity context

The extracted context around Interferon-lambda receptor shows recurring relationship patterns in the source. For example, Interferon-lambda receptor → IL28RA, CRF2/12, IFNLR, IL-28R1 Another extracted example is Interferon-lambda receptor → InterPro. Use these groups to spot repeated connection types before inspecting the individual relationships.

Interferon-lambda receptor

Top relations

Alt. symbols · 1
Interferon-lambda receptor → IL28RA, CRF2/12, IFNLR, IL-28R1
Domains · 1
Interferon-lambda receptor → InterPro
HGNC · 1
Interferon-lambda receptor → 18584
Locus · 1
Interferon-lambda receptor → Chr. 1 p36.11
NCBI gene · 1
Interferon-lambda receptor → 163702
OMIM · 1
Interferon-lambda receptor → 607404
RefSeq · 1
Interferon-lambda receptor → NM_170743
Search for · 1
Interferon-lambda receptor → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Interferon-lambda receptor → Swiss-model
Symbol · 1
Interferon-lambda receptor → IFNLR1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor type cells signaling interferons also interferon ifnlr1 ifnlr expression cell binding chain cytokine found two monocytes gene il10rb result

Interferon-lambda receptor relationships Subject–Predicate–Object triples

TTTA extracted 33 structured relationships around Interferon-lambda receptor. Examples in this analysis include Interferon-lambda receptor → Alt. symbols → IL28RA, CRF2/12, IFNLR, IL-28R1 and Interferon-lambda receptor → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Interferon-lambda receptorAlt. symbolsIL28RA, CRF2/12, IFNLR, IL-28R11.00infobox
Interferon-lambda receptorDomainsInterPro1.00infobox
Interferon-lambda receptorHGNC185841.00infobox
Interferon-lambda receptorLocusChr. 1 p36.111.00infobox
Interferon-lambda receptorNCBI gene1637021.00infobox
Interferon-lambda receptorOMIM6074041.00infobox
Interferon-lambda receptorRefSeqNM_1707431.00infobox
Interferon-lambda receptorSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Interferon-lambda receptorStructuresSwiss-model1.00infobox
Interferon-lambda receptorSymbolIFNLR11.00infobox
Interferon-lambda receptorUniProtQ8IU571.00infobox
IL-10instance ofThe β chain is also used in the receptors for other cytokines0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Interferon-lambda receptor bring nearby vocabulary together. In this analysis, examples include Type, Also and Signaling. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Interferon-lambda receptor
    • Type
    • Also
    • Signaling
    • Binding
    • Interferons
    • Found
    • Cells
    • Cell
    • Chains
    • Epithelial
    • Ii
    • Il10rb
  • interferon-lambda receptor
    • Type
    • Also
    • Signaling
    • Binding
    • Interferons
    • Found
    • Cells
    • Cell
    • Chains
    • Epithelial
    • Ii
    • Il10rb
  • type ii cytokine receptor
    • Cytokine
    • Ii
    • Type
    • Chains
    • Epithelial
    • Ifnlr
    • Il10rb
    • Interleukin-28
    • Known
    • Largely
    • P36
    • Also
  • interleukin-10 receptor
    • Type
    • Also
    • Signaling
    • Binding
    • Interferons
    • Found
    • Cells
    • Cell
    • Chains
    • Epithelial
    • Ii
    • Il10rb
  • type 1 interferon receptor
    • Type
    • Also
    • Signaling
    • Binding
    • Two
    • Interferons
    • Found
    • Cells
    • Cell
    • Expression
    • Chains
    • Epithelial
  • type iii interferons
    • Type
    • Binding
    • Results
    • Signaling
    • Receptor
    • Also
    • Activation
    • Include
    • Jak
    • Pathway
    • Stat
    • Types
  • dendritic cells
    • Expression
    • Interferon
    • Epithelial
    • Largely
    • Also
    • Receptor
    • Found
    • Cell
    • Ifnlr
    • Signaling
    • Type
    • Ii
  • natural killer cells
    • Expression
    • Interferon
    • Epithelial
    • Largely
    • Also
    • Receptor
    • Found
    • Cell
    • Ifnlr
    • Signaling
    • Type
    • Ii

Connections between topic areas Semantic bridges

For Interferon-lambda receptor, one of the stronger structural bridges in this analysis connects Interferon-lambda receptor with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Interferon-lambda receptorFunction · splits 30 ⟂ 23
Interferon-lambda receptorOverview · splits 41 ⟂ 12
Interferon-lambda receptorLocation · splits 43 ⟂ 10
Interferon-lambda receptorStructure · splits 48 ⟂ 5

Map overview Semantic statistics

Interferon-lambda receptor

Nodes53
Edges52
Triples33
Avg. degree1.96
Density0.037736
Components1

Source & methodology

TTTA analyzes the structure around Interferon-lambda receptor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Geography, Function & Location, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Interferon-lambda receptor · EN edition · Analysis: TopicsToTalkAbout

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