Excitatory amino acid transporter 2

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As a drug target

Neurotransmission DL-TBOA WAY-213,613 Dihydrokainic acid Nerve agent

16 related topics

Clinical significance

Amyotrophic lateral sclerosis Riluzole Ceftriaxone Prepulse inhibition Sensory gating

5 related topics

Function

Solute carrier family Neurotransmitter Glutamate Glutamate receptors

4 related topics

Interactions

Interact AJUBA

2 related topics

Key facts & relationships

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Aliases: SLC1A2, EAAT2, GLT-1, HBGT, solute carrier family 1 member 2, EIEE41, DEE41
Band: 11p13 · 2 E2|2 54.13 cM
Bgee: endothelial cell · Brodmann area 23 · entorhinal cortex · external globus pallidus · middle temporal gyrus
BioGPS: More reference expression data
Chr.: Chromosome 11 (human) · Chromosome 2 (mouse)
Databases: NCBI: entry; OMA: entry

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Overview

Function

Clinical significance

Interactions

Interact Protein-protein interaction
AJUBA

As a drug target

Advanced semantic analysis

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Map overview Semantic statistics

Nodes35

Edges34

Triples101

Avg. degree1.94

Density0.057143

Components1

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Excitatory amino acid transporter 2

Top relations

Gene ontology · 38

Excitatory amino acid transporter 2 → adult behavior, amino acid transmembrane transporter activity, amino acid transport, anion transmembrane transport, anion transmembrane transporter activity, axolemma, axon, cell surface, cellular response to extracellular stimulus, chemical synaptic transmission, D-aspartate import across plasma membrane, glutamate secretion, glutamate:sodium symporter activity, glutamatergic synapse, high-affinity glutamate transmembrane transporter activity, integral component of membrane, integral component of plasma membrane, integral component of presynaptic membrane, ion transport, L-glutamate import across plasma membrane

Bgee · 20

Excitatory amino acid transporter 2 → anterior amygdaloid area, Brodmann area 23, caudate nucleus, deep cerebellar nuclei, endothelial cell, entorhinal cortex, external globus pallidus, globus pallidus, internal globus pallidus, lateral septal nucleus, mammillary body, medial dorsal nucleus, medial geniculate nucleus, middle temporal gyrus, nucleus accumbens, olfactory tubercle, parietal lobe, postcentral gyrus, Rostral migratory stream, subiculum

RNA expression pattern · 20

Band · 2

Excitatory amino acid transporter 2 → 11p13, 2 E2|2 54.13 cM

Chr. · 2

Excitatory amino acid transporter 2 → Chromosome 11 (human), Chromosome 2 (mouse)

End · 2

Excitatory amino acid transporter 2 → 102,621,129 bp, 35,420,063 bp

Aliases · 1

Excitatory amino acid transporter 2 → SLC1A2, EAAT2, GLT-1, HBGT, solute carrier family 1 member 2, EIEE41, DEE41

BioGPS · 1

Excitatory amino acid transporter 2 → More reference expression data

Databases · 1

Excitatory amino acid transporter 2 → NCBI: entry; OMA: entry

Ensembl · 1

Excitatory amino acid transporter 2 → ENSG00000110436

Important terminology Word statistics

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Important terminology

eaat2 glutamate expression gene bp glt-1 slc1a2 chr human band protein transporter chromosome 11 solute carrier family function known drug

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Excitatory amino acid transporter 2	Aliases	SLC1A2, EAAT2, GLT-1, HBGT, solute carrier family 1 member 2, EIEE41, DEE41	1.00	infobox
Excitatory amino acid transporter 2	Band	11p13	1.00	infobox
Excitatory amino acid transporter 2	Band	2 E2\|2 54.13 cM	1.00	infobox
Excitatory amino acid transporter 2	Bgee	endothelial cell	1.00	infobox
Excitatory amino acid transporter 2	Bgee	Brodmann area 23	1.00	infobox
Excitatory amino acid transporter 2	Bgee	entorhinal cortex	1.00	infobox
Excitatory amino acid transporter 2	Bgee	external globus pallidus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	middle temporal gyrus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	parietal lobe	1.00	infobox
Excitatory amino acid transporter 2	Bgee	postcentral gyrus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	internal globus pallidus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	nucleus accumbens	1.00	infobox
Excitatory amino acid transporter 2	Bgee	caudate nucleus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	lateral septal nucleus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	olfactory tubercle	1.00	infobox
Excitatory amino acid transporter 2	Bgee	subiculum	1.00	infobox
Excitatory amino acid transporter 2	Bgee	anterior amygdaloid area	1.00	infobox
Excitatory amino acid transporter 2	Bgee	globus pallidus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	deep cerebellar nuclei	1.00	infobox
Excitatory amino acid transporter 2	Bgee	mammillary body	1.00	infobox
Excitatory amino acid transporter 2	Bgee	medial dorsal nucleus	1.00	infobox
Excitatory amino acid transporter 2	Bgee	Rostral migratory stream	1.00	infobox
Excitatory amino acid transporter 2	Bgee	medial geniculate nucleus	1.00	infobox
Excitatory amino acid transporter 2	BioGPS	More reference expression data	1.00	infobox
Excitatory amino acid transporter 2	Chr.	Chromosome 11 (human)	1.00	infobox
Excitatory amino acid transporter 2	Chr.	Chromosome 2 (mouse)	1.00	infobox
Excitatory amino acid transporter 2	Databases	NCBI: entry; OMA: entry	1.00	infobox
Excitatory amino acid transporter 2	End	35,420,063 bp	1.00	infobox
Excitatory amino acid transporter 2	End	102,621,129 bp	1.00	infobox
Excitatory amino acid transporter 2	Ensembl	ENSG00000110436	1.00	infobox

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