CDKN2B

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Explore the main themes, entities and connections around CDKN2B. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Tumor suppressor CDKN2A Cyclin-dependent kinase inhibitor CDK4 CDK6

7 related topics

Interactions

Interact Cyclin-dependent kinase 4

2 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b, cyclin-dependent kinase inhibitor 2B, cyclin dependent kinase inhibitor 2B
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D9S
Band: 9p21.3 · 4 C4|4 42.15 cM
Bgee: jejunal mucosa · mucosa of colon · mucosa of sigmoid colon · oral cavity · mucosa of transverse colon
BioGPS: More reference expression data
Chr.: Chromosome 9 (human) · Chromosome 4 (mouse)

Topics to explore

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Overview

Function

Tumor suppressor Tumor suppressor gene
CDKN2A P16 (gene)
Cyclin-dependent kinase inhibitor Cyclin-dependent kinase inhibitor protein
CDK4
CDK6
Cyclin D
TGF beta Transforming growth factor beta

Interactions

Interact Protein-protein interaction
Cyclin-dependent kinase 4

Advanced semantic analysis

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Map overview Semantic statistics

Nodes15

Edges14

Triples86

Avg. degree1.87

Density0.133333

Components1

How this topic connects Entity context

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CDKN2B

Top relations

Gene ontology · 22

CDKN2B → cell cycle, cellular response to extracellular stimulus, cellular response to nutrient, cellular senescence, cyclin-dependent protein serine/threonine kinase inhibitor activity, cytoplasm, cytosol, G2/M transition of mitotic cell cycle, megakaryocyte differentiation, mitotic cell cycle checkpoint signaling, negative regulation of cell population proliferation, negative regulation of cyclin-dependent protein serine/threonine kinase activity, negative regulation of epithelial cell proliferation, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of phosphorylation, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transforming growth factor beta receptor signaling pathway, protein binding, protein kinase binding

Bgee · 20

CDKN2B → buccal mucosa cell, calvaria, conjunctival fornix, duodenum, endothelial cell of lymphatic vessel, epithelium of stomach, gums, ileum, jejunal mucosa, jejunum, left colon, mucosa of colon, mucosa of sigmoid colon, mucosa of transverse colon, mucous cell of stomach, oral cavity, rectum, right lung lobe, skin of hip, transitional epithelium of urinary bladder

RNA expression pattern · 20

Band · 2

CDKN2B → 4 C4|4 42.15 cM, 9p21.3

Chr. · 2

CDKN2B → Chromosome 4 (mouse), Chromosome 9 (human)

End · 2

CDKN2B → 22,009,305 bp, 89,229,276 bp

Aliases · 1

CDKN2B → CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b, cyclin-dependent kinase inhibitor 2B, cyclin dependent kinase inhibitor 2B

Available structures · 1

CDKN2B → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D9S

BioGPS · 1

CDKN2B → More reference expression data

Databases · 1

CDKN2B → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

gene human bp chr band cyclin-dependent kinase inhibitor chromosome location protein p15ink4b tumor suppressor mouse growth ucsc function external also

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
CDKN2B	Aliases	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b, cyclin-dependent kinase inhibitor 2B, cyclin dependent kinase inhibitor 2B	1.00	infobox
CDKN2B	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1D9S	1.00	infobox
CDKN2B	Band	9p21.3	1.00	infobox
CDKN2B	Band	4 C4\|4 42.15 cM	1.00	infobox
CDKN2B	Bgee	jejunal mucosa	1.00	infobox
CDKN2B	Bgee	mucosa of colon	1.00	infobox
CDKN2B	Bgee	mucosa of sigmoid colon	1.00	infobox
CDKN2B	Bgee	oral cavity	1.00	infobox
CDKN2B	Bgee	mucosa of transverse colon	1.00	infobox
CDKN2B	Bgee	rectum	1.00	infobox
CDKN2B	Bgee	buccal mucosa cell	1.00	infobox
CDKN2B	Bgee	duodenum	1.00	infobox
CDKN2B	Bgee	skin of hip	1.00	infobox
CDKN2B	Bgee	gums	1.00	infobox
CDKN2B	Bgee	epithelium of stomach	1.00	infobox
CDKN2B	Bgee	jejunum	1.00	infobox
CDKN2B	Bgee	left colon	1.00	infobox
CDKN2B	Bgee	calvaria	1.00	infobox
CDKN2B	Bgee	ileum	1.00	infobox
CDKN2B	Bgee	endothelial cell of lymphatic vessel	1.00	infobox
CDKN2B	Bgee	mucous cell of stomach	1.00	infobox
CDKN2B	Bgee	transitional epithelium of urinary bladder	1.00	infobox
CDKN2B	Bgee	right lung lobe	1.00	infobox
CDKN2B	Bgee	conjunctival fornix	1.00	infobox
CDKN2B	BioGPS	More reference expression data	1.00	infobox
CDKN2B	Chr.	Chromosome 9 (human)	1.00	infobox
CDKN2B	Chr.	Chromosome 4 (mouse)	1.00	infobox
CDKN2B	Databases	NCBI: entry; OMA: entry	1.00	infobox
CDKN2B	End	22,009,305 bp	1.00	infobox
CDKN2B	End	89,229,276 bp	1.00	infobox

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