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Explore the main themes, entities and connections around Transcription factor II B. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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Structure
11 related topics
Phosphorylation
8 related topics
Clinical significance
8 related topics
Mechanism of action
7 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 2.3.1.48
- ↗
- Aliases
- GTF2B, TF2B, TFIIB, general transcription factor IIB
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C9B, 1DL6, 1RLY, 1RO4, 1TFB, 1VOL, 2PHG, 5IY7, 5IYA, 5IY6, 5IY9, 5IYB, 5IYD, 5IY8, 5IYC
- Band
- 1p22.2 · 3|3 H1
- Bgee
- oocyte · secondary oocyte · Achilles tendon · gingival epithelium · epithelium of nasopharynx
- BioGPS
- More reference expression data
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
- General transcription factor
- RNA polymerase II
- Preinitiation complex Transcription preinitiation complex
- Transcription Transcription (genetics)
- Nucleus Cell nucleus
- TATA-binding protein
- Archaeal transcription factor B
- Sigma factors Sigma factor
Structure
- Polypeptide Peptide
- Amino acids
- C-terminal C-terminus
- Amino terminal N-terminus
- Protein-protein interactions Protein-protein interaction
- Transcription factor IID
- RPB1 POLR2A
- Protein-DNA interactions Protein-DNA interaction
- B recognition element
- Promoter element Response element
- TATA element TATA box
Mechanism of action
- Phosphodiester bond
- Abortive transcripts Abortive initiation
- Active site
- Dissociation Dissociation (chemistry)
- NTPs Nucleoside triphosphate
- Magnesium ion Magnesium
- Yeast
Phosphorylation
- Phosphorylated Phosphorylation
- Serine
- TFIIH
- Kinase
- Mammalian Mammal
- Cell cycle
- Polyadenylation
- CstF-64 Cleavage stimulation factor
Similarities in other transcription complexes
Clinical significance
- In vitro
- Herpes simplex virus
- Cyclin A
- Replication Viral replication
- Cyclins Cyclin
- Polyglutamine tract
- Neurodegenerative diseases Neurodegeneration
- Brain
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.Transcription factor II B
Nodes52
Edges51
Triples105
Avg. degree1.96
Density0.038462
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
Transcription factor II B
Top relations
Gene ontology · 41
Transcription factor II B → acetyltransferase activity, acyltransferase activity, chromosome, DNA binding, DNA-templated transcription, initiation, histone acetylation, histone acetyltransferase activity, metal ion binding, nuclear body, nucleoplasm, nucleus, positive regulation by host of viral transcription, positive regulation of core promoter binding, positive regulation of transcription initiation from RNA polymerase II promoter, positive regulation of viral transcription, promoter-specific chromatin binding, protein acetylation, protein binding, protein-DNA complex, regulation of transcription, DNA-templated
Bgee · 19
Transcription factor II B → Achilles tendon, bone marrow, epithelium of nasopharynx, facial motor nucleus, gingival epithelium, islet of Langerhans, jejunum, medial ganglionic eminence, mucosa of sigmoid colon, olfactory zone of nasal mucosa, oocyte, palpebral conjunctiva, Paneth cell, primary oocyte, primitive streak, secondary oocyte, spermatid, spermatocyte, zygote
RNA expression pattern · 19
Transcription factor II B → Achilles tendon, bone marrow, epithelium of nasopharynx, facial motor nucleus, gingival epithelium, islet of Langerhans, jejunum, medial ganglionic eminence, mucosa of sigmoid colon, olfactory zone of nasal mucosa, oocyte, palpebral conjunctiva, Paneth cell, primary oocyte, primitive streak, secondary oocyte, spermatid, spermatocyte, zygote
Band · 2
Transcription factor II B → 1p22.2, 3|3 H1
Chr. · 2
Transcription factor II B → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
Transcription factor II B → 142,489,367 bp, 88,891,944 bp
2.3.1.48 · 1
Transcription factor II B → ↗
Aliases · 1
Transcription factor II B → GTF2B, TF2B, TFIIB, general transcription factor IIB
Available structures · 1
Transcription factor II B → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C9B, 1DL6, 1RLY, 1RO4, 1TFB, 1VOL, 2PHG, 5IY7, 5IYA, 5IY6, 5IY9, 5IYB, 5IYD, 5IY8, 5IYC
BioGPS · 1
Transcription factor II B → More reference expression data
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
tfiib rna transcription polymerase ii dna reader factor linker site complex gene bp found formation initiation binding chr human chromosome
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Transcription factor II B | 2.3.1.48 | ↗ | 1.00 | infobox |
| Transcription factor II B | Aliases | GTF2B, TF2B, TFIIB, general transcription factor IIB | 1.00 | infobox |
| Transcription factor II B | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C9B, 1DL6, 1RLY, 1RO4, 1TFB, 1VOL, 2PHG, 5IY7, 5IYA, 5IY6, 5IY9, 5IYB, 5IYD, 5IY8, 5IYC | 1.00 | infobox |
| Transcription factor II B | Band | 1p22.2 | 1.00 | infobox |
| Transcription factor II B | Band | 3|3 H1 | 1.00 | infobox |
| Transcription factor II B | Bgee | oocyte | 1.00 | infobox |
| Transcription factor II B | Bgee | secondary oocyte | 1.00 | infobox |
| Transcription factor II B | Bgee | Achilles tendon | 1.00 | infobox |
| Transcription factor II B | Bgee | gingival epithelium | 1.00 | infobox |
| Transcription factor II B | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| Transcription factor II B | Bgee | bone marrow | 1.00 | infobox |
| Transcription factor II B | Bgee | islet of Langerhans | 1.00 | infobox |
| Transcription factor II B | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| Transcription factor II B | Bgee | mucosa of sigmoid colon | 1.00 | infobox |
| Transcription factor II B | Bgee | palpebral conjunctiva | 1.00 | infobox |
| Transcription factor II B | Bgee | primary oocyte | 1.00 | infobox |
| Transcription factor II B | Bgee | zygote | 1.00 | infobox |
| Transcription factor II B | Bgee | spermatocyte | 1.00 | infobox |
| Transcription factor II B | Bgee | spermatid | 1.00 | infobox |
| Transcription factor II B | Bgee | medial ganglionic eminence | 1.00 | infobox |
| Transcription factor II B | Bgee | primitive streak | 1.00 | infobox |
| Transcription factor II B | Bgee | Paneth cell | 1.00 | infobox |
| Transcription factor II B | Bgee | jejunum | 1.00 | infobox |
| Transcription factor II B | Bgee | facial motor nucleus | 1.00 | infobox |
| Transcription factor II B | BioGPS | More reference expression data | 1.00 | infobox |
| Transcription factor II B | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| Transcription factor II B | Chr. | Chromosome 3 (mouse) | 1.00 | infobox |
| Transcription factor II B | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Transcription factor II B | End | 88,891,944 bp | 1.00 | infobox |
| Transcription factor II B | End | 142,489,367 bp | 1.00 | infobox |
No triples extracted yet.
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