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GRIN2D: Measurement, Function & Interactions

Glutamate receptor subunit epsilon-4 is a protein that in humans is encoded by the GRIN2D gene.

Language: English [EN]
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GRIN2D topic overview

The analysis highlights Measurement, Function and Interactions as prominent areas in the source structure around GRIN2D.

Related topics
8
Source areas
3
Connected nodes
11
Extracted relationships
110
Concept neighborhoods
6
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 4 topics
Interactions · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GRIN2D, EB11, GluN2D, NMDAR2D, NR2D, glutamate ionotropic receptor NMDA type subunit 2D, EIEE46, DEE46
Band
19q13.33 · 7 B3|7 29.54 cM
Bgee
cingulate gyrus · anterior cingulate cortex · prefrontal cortex · ganglionic eminence · hypothalamus
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GRIN2D connects Entity context

The extracted context around GRIN2D shows recurring relationship patterns in the source. For example, GRIN2D → adult locomotory behavior, brain development, calcium ion transmembrane import into cytosol, calcium-mediated signaling, cell junction, excitatory chemical synaptic transmission, excitatory postsynaptic potential, extracellularly glutamate-gated ion channel activity, glutamate-gated calcium ion channel activity, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, ion channel activity, ion transport, ionotropic glutamate receptor activity, ionotropic glutamate receptor signaling pathway, long-term potentiation, MAPK cascade, membrane, NMDA glutamate receptor activity Another extracted example is GRIN2D → amygdala, anterior cingulate cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, dorsomedial hypothalamic nucleus, ganglionic eminence, hypothalamus, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, molar, molecular layer of cerebellar cortex, neural layer of retina, prefrontal cortex, primary visual cortex, right frontal lobe, seminiferous tubule, spermatocyte, superior frontal gyrus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

GRIN2D

Top relations

Gene ontology · 31
GRIN2D → adult locomotory behavior, brain development, calcium ion transmembrane import into cytosol, calcium-mediated signaling, cell junction, excitatory chemical synaptic transmission, excitatory postsynaptic potential, extracellularly glutamate-gated ion channel activity, glutamate-gated calcium ion channel activity, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, ion channel activity, ion transport, ionotropic glutamate receptor activity, ionotropic glutamate receptor signaling pathway, long-term potentiation, MAPK cascade, membrane, NMDA glutamate receptor activity
Bgee · 20
GRIN2D → amygdala, anterior cingulate cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, dorsomedial hypothalamic nucleus, ganglionic eminence, hypothalamus, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, molar, molecular layer of cerebellar cortex, neural layer of retina, prefrontal cortex, primary visual cortex, right frontal lobe, seminiferous tubule, spermatocyte, superior frontal gyrus, ventricular zone
RNA expression pattern · 20
GRIN2D → amygdala, anterior cingulate cortex, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, dorsomedial hypothalamic nucleus, ganglionic eminence, hypothalamus, lateral nuclear group of thalamus, lumbar subsegment of spinal cord, molar, molecular layer of cerebellar cortex, neural layer of retina, prefrontal cortex, primary visual cortex, right frontal lobe, seminiferous tubule, spermatocyte, superior frontal gyrus, ventricular zone
related to Function · 12
GRIN2D → GRIN1, GRIN2A, GRIN2B, GRIN2C, N-methyl-D-aspartate, NMDA, NMDAR1, NMDAR2, NMDAR2A, NMDAR2B, NMDAR2C, NMDAR2D
related to External links · 6
GRIN2D → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
Band · 2
GRIN2D → 19q13.33, 7 B3|7 29.54 cM
Chr. · 2
GRIN2D → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
GRIN2D → 45,878,378 bp, 48,444,931 bp
Aliases · 1
GRIN2D → GRIN2D, EB11, GluN2D, NMDAR2D, NR2D, glutamate ionotropic receptor NMDA type subunit 2D, EIEE46, DEE46
BioGPS · 1
GRIN2D → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nmda bp human chr band glutamate receptor gene chromosome 19 protein subunit location ionotropic mouse function external 444 931 end

GRIN2D relationships Subject–Predicate–Object triples

TTTA extracted 110 structured relationships around GRIN2D. Examples in this analysis include GRIN2D → Aliases → GRIN2D, EB11, GluN2D, NMDAR2D, NR2D, glutamate ionotropic receptor NMDA type subunit 2D, EIEE46, DEE46 and GRIN2D → Band → 19q13.33. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GRIN2DAliasesGRIN2D, EB11, GluN2D, NMDAR2D, NR2D, glutamate ionotropic receptor NMDA type subunit 2D, EIEE46, DEE461.00infobox
GRIN2DBand19q13.331.00infobox
GRIN2DBand7 B3|7 29.54 cM1.00infobox
GRIN2DBgeecingulate gyrus1.00infobox
GRIN2DBgeeanterior cingulate cortex1.00infobox
GRIN2DBgeeprefrontal cortex1.00infobox
GRIN2DBgeeganglionic eminence1.00infobox
GRIN2DBgeehypothalamus1.00infobox
GRIN2DBgeeventricular zone1.00infobox
GRIN2DBgeeright frontal lobe1.00infobox
GRIN2DBgeelateral nuclear group of thalamus1.00infobox
GRIN2DBgeeamygdala1.00infobox
GRIN2DBgeedorsolateral prefrontal cortex1.00infobox
GRIN2DBgeemolecular layer of cerebellar cortex1.00infobox
GRIN2DBgeelumbar subsegment of spinal cord1.00infobox
GRIN2DBgeemolar1.00infobox
GRIN2DBgeeprimary visual cortex1.00infobox
GRIN2DBgeeseminiferous tubule1.00infobox
GRIN2DBgeedorsomedial hypothalamic nucleus1.00infobox
GRIN2DBgeesuperior frontal gyrus1.00infobox
GRIN2DBgeespermatocyte1.00infobox
GRIN2DBgeedentate gyrus of hippocampal formation granule cell1.00infobox
GRIN2DBgeeneural layer of retina1.00infobox
GRIN2DBioGPSMore reference expression data1.00infobox
GRIN2DChr.Chromosome 19 (human)1.00infobox
GRIN2DChr.Chromosome 7 (mouse)1.00infobox
GRIN2DDatabasesNCBI: entry; OMA: entry1.00infobox
GRIN2DEnd48,444,931 bp1.00infobox
GRIN2DEnd45,878,378 bp1.00infobox
GRIN2DEnsemblENSG000001054641.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GRIN2D bring nearby vocabulary together. In this analysis, examples include Receptor, Nmda and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GRIN2D
    • Receptor
    • Nmda
    • Protein
    • Subunit
    • Human
    • Function
    • Ionotropic
    • Nmdar2d
    • Location
    • Chromosome
    • Bp
    • Chr
  • grin2d
    • Receptor
    • Nmda
    • Protein
    • Subunit
    • Human
    • Function
    • Ionotropic
    • Nmdar2d
    • Location
    • Chromosome
    • Bp
    • Chr
  • gene
    • Location
    • Chromosome
    • Glutamate
    • B3
    • Bp
    • Chr
    • End
    • Function
    • Human
    • Ionotropic
    • Mouse
    • Receptor
  • function
    • Ionotropic
    • Location
    • Also
    • Chromosome
    • External
    • Gene
    • Glutamate
    • Interactions
    • See
    • Bp
    • Chr
    • Human
  • protein
    • Receptor
    • Human
    • B3
    • Channel
    • End
    • Function
    • Ionotropic
    • Long-term
    • Mouse
    • Potentiation
    • Synaptic
    • Transmission
  • interactions
    • See
    • Ionotropic
    • Nmdar2d
    • Location
    • Subunit
    • Human
    • Receptor
    • Nmda

Connections between topic areas Semantic bridges

For GRIN2D, one of the stronger structural bridges in this analysis connects GRIN2D with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GRIN2DFunction · splits 7 ⟂ 5
GRIN2DOverview · splits 9 ⟂ 3
GRIN2DInteractions · splits 9 ⟂ 3

Map overview Semantic statistics

GRIN2D

Nodes12
Edges11
Triples110
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around GRIN2D to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GRIN2D · EN edition · Analysis: TopicsToTalkAbout

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