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GRIN1: Measurement & Overview

Glutamate Receptor Ionotropic, subunit zeta-1 is a protein that in humans is encoded by the GRIN1 gene.

Language: English [EN]
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GRIN1 topic overview

The analysis highlights Measurement and Overview as prominent areas in the source structure around GRIN1.

Related topics
9
Source areas
1
Connected nodes
10
Extracted relationships
169
Concept neighborhoods
10
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GRIN1, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1, NDHMSR, NDHMSD, DEE101
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HQW, 2NR1, 3BYA, 5H8N, 5H8H, 5H8Q, 5H8F, 5I2N, 5I2K, 5KCJ, 5KDT
Band
9q34.3 · 2 A3|2 17.14 cM
Bgee
right hemisphere of cerebellum · right frontal lobe · anterior cingulate cortex · nucleus accumbens · prefrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How GRIN1 connects Entity context

The extracted context around GRIN1 shows recurring relationship patterns in the source. For example, GRIN1 → adult locomotory behavior, amyloid-beta binding, associative learning, brain development, calcium channel activity, calcium ion binding, calcium ion homeostasis, calcium ion transmembrane import into cytosol, calcium ion transmembrane transport, calcium ion transport, calcium-mediated signaling, calmodulin binding, cation channel activity, cation transmembrane transport, cation transport, cell junction, cell surface, cellular calcium ion homeostasis, cellular response to amyloid-beta, cerebral cortex development Another extracted example is GRIN1 → amygdala, anterior cingulate cortex, Brodmann area 10, Brodmann area 9, CA3 field, caudate nucleus, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, molecular layer of cerebellar cortex, nucleus accumbens, perirhinal cortex, prefrontal cortex, primary motor cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior colliculus, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.

GRIN1

Top relations

Gene ontology · 106
GRIN1 → adult locomotory behavior, amyloid-beta binding, associative learning, brain development, calcium channel activity, calcium ion binding, calcium ion homeostasis, calcium ion transmembrane import into cytosol, calcium ion transmembrane transport, calcium ion transport, calcium-mediated signaling, calmodulin binding, cation channel activity, cation transmembrane transport, cation transport, cell junction, cell surface, cellular calcium ion homeostasis, cellular response to amyloid-beta, cerebral cortex development
Bgee · 20
GRIN1 → amygdala, anterior cingulate cortex, Brodmann area 10, Brodmann area 9, CA3 field, caudate nucleus, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, molecular layer of cerebellar cortex, nucleus accumbens, perirhinal cortex, prefrontal cortex, primary motor cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior colliculus, superior frontal gyrus
RNA expression pattern · 20
GRIN1 → amygdala, anterior cingulate cortex, Brodmann area 10, Brodmann area 9, CA3 field, caudate nucleus, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, molecular layer of cerebellar cortex, nucleus accumbens, perirhinal cortex, prefrontal cortex, primary motor cortex, primary visual cortex, putamen, right frontal lobe, right hemisphere of cerebellum, superior colliculus, superior frontal gyrus
Band · 2
GRIN1 → 2 A3|2 17.14 cM, 9q34.3
Chr. · 2
GRIN1 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
GRIN1 → 137,168,756 bp, 25,209,199 bp
Aliases · 1
GRIN1 → GRIN1, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1, NDHMSR, NDHMSD, DEE101
Available structures · 1
GRIN1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HQW, 2NR1, 3BYA, 5H8N, 5H8H, 5H8Q, 5H8F, 5I2N, 5I2K, 5KCJ, 5KDT
BioGPS · 1
GRIN1 → More reference expression data
Databases · 1
GRIN1 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human bp receptor chr band glutamate protein nmda chromosome subunits mouse subunit ionotropic location encoded plasticity memory learning channel

GRIN1 relationships Subject–Predicate–Object triples

TTTA extracted 169 structured relationships around GRIN1. Examples in this analysis include GRIN1 → Aliases → GRIN1, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1, NDHMSR, NDHMSD, DEE101 and GRIN1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HQW, 2NR1, 3BYA, 5H8N, 5H8H, 5H8Q, 5H8F, 5I2N, 5I2K, 5KCJ, 5KDT. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GRIN1AliasesGRIN1, GluN1, MRD8, NMDA1, NMDAR1, NR1, NMD-R1, glutamate ionotropic receptor NMDA type subunit 1, NDHMSR, NDHMSD, DEE1011.00infobox
GRIN1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HQW, 2NR1, 3BYA, 5H8N, 5H8H, 5H8Q, 5H8F, 5I2N, 5I2K, 5KCJ, 5KDT1.00infobox
GRIN1Band9q34.31.00infobox
GRIN1Band2 A3|2 17.14 cM1.00infobox
GRIN1Bgeeright hemisphere of cerebellum1.00infobox
GRIN1Bgeeright frontal lobe1.00infobox
GRIN1Bgeeanterior cingulate cortex1.00infobox
GRIN1Bgeenucleus accumbens1.00infobox
GRIN1Bgeeprefrontal cortex1.00infobox
GRIN1BgeeBrodmann area 91.00infobox
GRIN1Bgeeputamen1.00infobox
GRIN1Bgeeamygdala1.00infobox
GRIN1Bgeecaudate nucleus1.00infobox
GRIN1BgeeBrodmann area 101.00infobox
GRIN1Bgeeperirhinal cortex1.00infobox
GRIN1Bgeeentorhinal cortex1.00infobox
GRIN1Bgeeprimary visual cortex1.00infobox
GRIN1Bgeesuperior frontal gyrus1.00infobox
GRIN1BgeeCA3 field1.00infobox
GRIN1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
GRIN1Bgeecerebellar cortex1.00infobox
GRIN1Bgeesuperior colliculus1.00infobox
GRIN1Bgeemolecular layer of cerebellar cortex1.00infobox
GRIN1Bgeeprimary motor cortex1.00infobox
GRIN1BioGPSMore reference expression data1.00infobox
GRIN1Chr.Chromosome 9 (human)1.00infobox
GRIN1Chr.Chromosome 2 (mouse)1.00infobox
GRIN1DatabasesNCBI: entry; OMA: entry1.00infobox
GRIN1End137,168,756 bp1.00infobox
GRIN1End25,209,199 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around GRIN1 bring nearby vocabulary together. In this analysis, examples include Ionotropic, Nmda and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Glutamate
    • Receptor
    • Grin1
    • Ionotropic
    • Location
    • Nmda
    • Protein
    • Subunit
    • Chromosome
    • Bp
    • Chr
    • Human
  • glutamate receptor
    • Receptor
    • Grin1
    • Ionotropic
    • Nmda
    • Protein
    • Subunit
    • Gene
    • Channel
    • Encoded
    • Ion
    • Search
    • Location
  • ligand-gated ion channel
    • Ion
    • Protein
    • Critical
    • Glutamate
    • Receptor
    • A3
    • Encoded
    • End
    • Expression
    • Gene
    • Learning
    • Memory
  • GRIN1
    • Ionotropic
    • Nmda
    • Receptor
    • Search
    • Location
    • Protein
    • Subunit
    • Chromosome
    • Bp
    • Chr
    • Human
    • Humans
  • grin1
    • Ionotropic
    • Nmda
    • Receptor
    • Search
    • Location
    • Protein
    • Subunit
    • Chromosome
    • Bp
    • Chr
    • Human
    • Humans
  • protein
    • Receptor
    • Channel
    • Ion
    • Grin1
    • Subunit
    • Critical
    • Humans
    • Zeta-1
    • A3
    • End
    • Expression
    • Learning
  • plasticity
    • Learning
    • Memory
    • Synapses
    • A3
    • End
    • Expression
    • Search
    • Location
    • Mouse
    • Protein
    • Subunits
    • Band
  • synapses
    • Learning
    • Memory
    • Plasticity
    • Subunits

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the GRIN1 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

GRIN1

Nodes11
Edges10
Triples169
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around GRIN1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GRIN1 · EN edition · Analysis: TopicsToTalkAbout

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